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  • patients
  • To evaluate the usefulness of methyl guanine methyltransferase (MGMT) status (by immunohistochemistry [IHC] and promoter methylation) for predicting response in pancreatic neuroendocrine tumor patients treated with either temozolomide or temozolomide and capecitabine. (clinicaltrials.gov)
  • pulmonary
  • Pulmonary neuroendocrine tumors are neuroendocrine tumors localized to the lung: bronchus or pulmonary parenchyma. (wikipedia.org)
  • Hypothalamic-pituitary-adrenal axis (HPA axis) Hypothalamic-pituitary-thyroid axis (HPT axis) Hypothalamic-pituitary-gonadal axis (HPG axis) Hypothalamic-neurohypophyseal system Pulmonary neuroendocrine cells (PNEC) are specialized airway epithelial cells that occur as solitary cells or as clusters called neuroepithelial bodies (NEB) in the lung. (wikipedia.org)
  • occur
  • Hindgut tumors occur less frequently and are found in parts of the colon and in the rectum. (encyclopedia.com)
  • Neuroendocrine tumors are rare and can occur anywhere in the body. (mayoclinic.org)
  • citation needed] The term multiple endocrine neoplasia is used when two or more endocrine tumor types, known to occur as a part of one of the defined MEN syndromes, occurs in a single patient and there is evidence for either a causative mutation or hereditary transmission. (wikipedia.org)
  • The presence of two or more tumor types in a single patient does not automatically designate that individual as having MEN because there is a small statistical chance that development of two "sporadic" tumors that occur in one of the MEN syndromes could occur by chance. (wikipedia.org)
  • diagnosis
  • It describes how to cope with challenges in everyday life after a diagnosis of a tumor. (cancer.net)
  • Worsened survival was associated with older age, tumor site, advanced stage, and earlier year of diagnosis. (hindawi.com)
  • The diagnosis of an insulinoma is usually made biochemically with low blood glucose, elevated insulin, proinsulin, and C-peptide levels, and confirmed by localizing the tumor with medical imaging or angiography. (wikipedia.org)
  • parathyroid
  • Tumors with similar cellular characteristics in the pituitary, parathyroid, and adrenomedullary glands are sometimes included or excluded. (wikipedia.org)
  • primitive neuro
  • Not to be confused with primitive neuroectodermal tumor , which is also abbreviated as PNET. (wikipedia.org)
  • PanNETs are sometimes abbreviated as PETs or PNETs: such use should not to be confused with the primitive neuroectodermal tumor (PNET). (wikipedia.org)
  • 2016
  • Researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) presented a molecular imaging methodology that allows the increase of the radiotherapy dose to the tumor while protecting vulnerable vital organs.1 The delicate balance of administering the. (ascopost.com)
  • In a subgroup analysis of the phase III RADIANT-4 trial, focusing on neuroendocrine tumors of gastrointestinal origin, the mTOR inhibitor everolimus (Afinitor) essentially doubled the median progression-free survival time, compared with placebo, researchers reported at the 2016 Gastrointestinal. (ascopost.com)
  • epithelial
  • Keratin 8 is often used together with keratin 18 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood. (wikipedia.org)
  • shrinkage
  • In practice, hepatic artery embolization occludes the blood flow to the tumors, achieving significant tumor shrinkage in over 80% of people. (wikipedia.org)
  • By occluding the blood supply to the tumors, achieving significant tumor shrinkage in over 80% of people. (wikipedia.org)
  • malignant tumor
  • In order for a LCLC to be subclassified as the rhabdoid phenotype variant, at least 10% of the malignant tumor cells must contain distinctive structures composed of tangled intermediate filaments that displace the cell nucleus outward toward the cell membrane. (wikipedia.org)
  • cells
  • Neuroendocrine tumors are tumors that develop from the cells of the diffuse neuroendocrine system, such as the enterochromaffin (EC) cells. (encyclopedia.com)
  • These tumors are characterized by the presence of cells that possess secretory granules and have the ability to secrete neurohormones. (encyclopedia.com)
  • The neuroendocrine system cells are specialized endocrine cells of the nervous system and produce neurohormones. (encyclopedia.com)
  • Neuroendocrine cells have traits similar to nerve cells and to hormone-producing cells. (mayoclinic.org)
  • If you do imaging with dotatate, then you can know up front whether the dotatate [in the lutetium Lu 177 dotatate] is likely to be taken up by the tumor" and help kill the tumor cells. (cancer.gov)
  • A tumor can recur because small areas of tumor cells may remain undetected in the body. (cancer.net)
  • Rare and slow growing carcinoid and non-carcinoid tumors develop from these cells. (wikipedia.org)
  • The several types of hepatic artery treatments are based on the observation that tumor cells get nearly all their nutrients from the hepatic artery, while the normal cells of the liver get about 70-80 percent of their nutrients and 50% their oxygen supply from the portal vein, and thus can survive with the hepatic artery effectively blocked. (wikipedia.org)
  • Tumor cells get over 90% of their nutrients from the hepatic artery, while the normal cells of the liver get about 70-80 percent of their nutrients and 50% their oxygen supply from the portal vein, and thus can survive with the hepatic artery effectively blocked. (wikipedia.org)
  • Specialized groups of neuroendocrine cells can be found at the base of the third ventricle in the brain (in a region called the hypothalamus). (wikipedia.org)
  • incidence
  • Much of the apparent rise in new diagnoses may reflect incidental detection of NET through the increased use of imaging modalities such as computed tomography (CT) scans and endoscopic procedures for other indications rather than a true increase in tumor incidence. (hindawi.com)
  • sympathetic nervou
  • Extra-adrenal paragangliomas (often described as extra-adrenal pheochromocytomas) are closely related, though less common, tumors that originate in the ganglia of the sympathetic nervous system and are named based upon the primary anatomical site of origin. (wikipedia.org)
  • Neoplasms include: Pheochromocytoma (most common), a catecholamine-secreting tumor of the adrenal medulla Neuroblastoma, a neuroendocrine tumor of any neural crest tissue of the sympathetic nervous system Ganglioneuroma, a tumor in the nerve cells of the peripheral nervous system The adrenal medulla may be poorly formed or absent in cases of absent adrenal gland. (wikipedia.org)
  • adrenal
  • Pheochromocytoma (PCC) is a neuroendocrine tumor of the medulla of the adrenal glands (originating in the chromaffin cells), or extra-adrenal chromaffin tissue that failed to involute after birth, that secretes high amounts of catecholamines, mostly norepinephrine, plus epinephrine to a lesser extent. (wikipedia.org)
  • clinical
  • The fraction of Ki-67-positive tumor cells (the Ki-67 labeling index) is often correlated with the clinical course of cancer. (wikipedia.org)
  • survival
  • For these types of tumors, the prognostic value for survival and tumor recurrence have repeatedly been proven in uni- and multivariate analysis. (wikipedia.org)
  • tissue
  • This study will also look at specific substances called biomarkers in your blood, and in the tumor tissue which are involved in the growth of tumor cells, and determine if the levels of these biomarkers are related to your response to treatment or development of side effects. (clinicaltrials.gov)
  • receptor
  • In central nervous system structures, the glucocorticoid receptor is gaining interest as a novel representative of neuroendocrine integration, functioning as a major component of endocrine influence - specifically the stress response - upon the brain. (wikipedia.org)
  • site
  • OncologyPRO has evolved in July 2017 to offer you direct access to our rich content either by tumour site or according to the objectives of your visit. (esmo.org)
  • treatment
  • The safety and efficacy of zoledronic acid in the treatment of hypercalcemia associated with hyperparathyroidism or with other non-tumor-related conditions has not been established. (whatismedicalinsurancebilling.org)
  • The preferred treatment for esthesioneuroblastoma is surgery followed by radiotherapy to prevent reoccurrence of the tumor. (wikipedia.org)
  • less
  • Proton radiotherapy has recently been shown to be effective in a 10-person study with Kadish C tumors, while delivering less toxicity to the nervous system. (wikipedia.org)