Neuroendocrine systems involving arginine vasopressin. Medical search. Frequent questions

According to this model, stress can activate the central nervous system and the hypothalamus releases corticotropin-releasing hormone and arginine vasopressin that stimulates the release of adrenocorticotropin from the pituitary, which in turn results in the production of cortisol by the adrenal cortex. (nature.com)
This interaction takes place as Arginine Vasopressin works with corticotropin releasing hormone to stimulate the pituitary gland to secrete ACTH. (wikipedia.org)
In response to a stressor, the paraventricular nucleus (PVN) of the hypothalamus releases corticotropin releasing hormone (CRH) and arginine vasopressin (AVP). (encyclopedia.pub)

Interestingly, such effects increase with the passage of time, possibly reflecting diverse processes including such things as phenotypic changes of CRH neurons within the external zone of the median eminence so that the terminals coexpress both CRH and arginine vasopressin. (aku.edu)
The neurons that extend into the posterior pituitary produce either the hormone arginine vasopressin (abbreviated AVP) or the hormone oxytocin. (pharmaceuticalintelligence.com)
The AVP-producing (arginine-vasopressin, related to angiotensin and vasopressin peptides) neurons respond to signals relating to thirst and water regulation. (pharmaceuticalintelligence.com)
Some stressors involve an immediate threat to physiological homeostasis and require the rapid relay of peripheral signals to PVN neurons via direct serotonergic or catecholaminergic projections from brainstem nuclei [ 9 , 11 ]. (nature.com)
The behavioral data was cross-referenced with the number of neurons expressing oxytocin and arginine vasopressin, as well as the density of dopaminergic neurons (identified by the expression of tyrosine hydroxylase), in the paraventricular nucleus of the hypothalamus. (biomedcentral.com)
In this study, neurons expressing OT, arginine vasopressin (AVP), or tyrosine-hydroxylase (TH) (dopaminergic neurons), were counted in the PVN of prairie voles. (biomedcentral.com)
The role of PVN neuropeptides, such as CRF, oxytocin and vasopressin, in nicotine-stimulated ACTH secretion will be defined using cfos/neuropeptide colocalization to identify activated parvocellular PVN neurons. (grantome.com)
It has been implicated in multiple forms of neural plasticity, and active (de) methylation is an important regulator of gene expression in adult neurons involved in learning and memory [ 18 , 19 , 20 ]. (biomedcentral.com)
It is well known that neurons of the peripheral nervous system have the capacity to regenerate a severed axon leading to functional recovery, whereas neurons of the central nervous system do not regenerate suc. (biomedcentral.com)

Vasopressin V1b receptor (V1BR) also known as vasopressin 3 receptor (VPR3) or antidiuretic hormone receptor 1B is a protein that in humans is encoded by the AVPR1B (arginine vasopressin receptor 1B) gene. (wikipedia.org)
AVPR1B maps to chromosome region 1q32 and is a member of the vasopressin/oxytocin family subfamily. (wikipedia.org)
AVPR1B was initially described as a novel vasopressin receptor located in the anterior pituitary, where it stimulates ACTH release. (wikipedia.org)
AVPR1B is responsible for fueling the effects of vasopressin on ACTH release. (wikipedia.org)
AVPR1b is then responsible for mediating the stimulatory effect of vasopressin on ACTH release. (wikipedia.org)
Several G proteins are also involved in the signal transduction pathways linked with AVPR1B. (wikipedia.org)
The arginine vasopressin 1b receptor (Avpr1b) is involved in the modulation of a variety of behaviors and is an important part of the mammalian hormonal stress axis. (frontiersin.org)
Given the complexity of the central Avp system, as well as the many behaviors Avp is known to affect, this review will focus on the role of Avp signaling via the Avpr1b in the modulation of behaviors such as social memory and aggression as well as the importance of this system to the functioning of the hypothalamic-pituitary-adrenal (HPA) axis. (frontiersin.org)

Oxytocin is synthesized in the hypothalamus and is widely involved in social cognition and social behaviors, such as attachment. (psych.ac.cn)
This includes the hypothalamus, which influences neuroendocrine processes, as well as extrahypothalamic regions, such as the amygdala and prefrontal cortex, which are involved in fear and anxiety. (aku.edu)
Glucocorticoid treatment is associated with decreased expression of processed AVP but not of proAVP, neurophysin or oxytocin in the human hypothalamus: are PC1 and PC2 involved? (nel.edu)
We reported earlier that vasopressin (AVP) peptide expression is significantly decreased in the postmortem hypothalamus of glucocorticoid (GC) treated patients, while such a decrease was not observed in AVP prohormone (proAVP) expression. (nel.edu)
The hypothalamus is a small, yet vitally important, brain region that integrates the body's two communication systems: the endocrine and nervous systems. (pharmaceuticalintelligence.com)
Systemic vasopressin (VP) and oxytocin (OT) are chiefly produced by magnocellular neurosecretory cells (MNCs) in the supraoptic (SON) and paraventricular (PVN) nuclei of the hypothalamus. (jneurosci.org)
In fish, in analogy with mammals, the stress response consists of the activation of the sympathetic nervous system, as well as the hypothalamus-pituitary-interrenal axis (HPI). (silverchair.com)

Three speakers focused on the essential roles of vasopressin (i.e., the antidiuretic hormone) and its surrogate (copeptin) in the sensation of thirst and as a biomarker of renal diseases. (thefactsaboutwater.org)

Synthetic analogue of hypothalamic/posterior pituitary hormone 8-arginine vasopressin (ADH) for treatment of central DI. (medscape.com)
The posterior pituitary is controlled by the nervous system. (medscape.com)

Arginine vasopressin has four receptors, each of which are located in different tissues and have specific functions. (wikipedia.org)
Comparative research in voles yields a model based on interspecies and intraspecies variation of the geography of oxytocin receptors and vasopressin V1a receptors in the forebrain. (scienceopen.com)
Excessive activation of the vasopressin type 2 (V2) receptor in the kidney leads to glomerular hyperfiltration and nephron loss, whereas stimulation of vasopressin V1a or V1b receptors in the liver, pancreas, and adrenal glands promotes catabolic metabolism for energy mobilization, enhancing glucose production and aggravating DKD. (bvsalud.org)
To address this gap, we explored vasopressin receptors and androgens in titi monkeys, a pair-bonding and biparental primate species. (bvsalud.org)

Here we demonstrate that a likely mechanism underlying the orexigenic action of RLN3 is RXFP3-mediated inhibition of oxytocin- and arginine-vasopressin-synthesizing paraventricular nucleus (PVN) magnocellular neurosecretory cells. (jneurosci.org)
The vasopressin (VP) magnocellular neurosecretory cells (MNCs) in the supraoptic and paraventricular (PVN) nuclei are regulated by estrogen and exhibit robust expression of estrogen receptor (ER)-β. (jneurosci.org)

Throughout evolution microorganisms of the human microbiome have developed systems for sensing host-associated signals such as hormones associated with those stressors, enabling them to recognize essential changes in their environment, thus changing their expression gene profile to fit the needs of the new environment. (nature.com)
The most widely accepted theory explaining the ability of hormones to affect the outcome of an infection involves the suppression of the immune system. (nature.com)
The most widely accepted theory to explain how hormones can influence microbial infections involves the of the immune system. (nature.com)
In addition, researchers can combine neuroimaging technologies with behavioral studies to clarify the neuroendocrine mechanism of these hormones affecting disgust processing. (psych.ac.cn)
The endocrine system-the other communication system in the body-is made up of endocrine glands that produce hormones, chemical substances released into the bloodstream to guide processes such as metabolism, growth, and sexual development. (medscape.com)
Hormones are also involved in regulating emotional life. (medscape.com)
It produces 2 hormones: vasopressin, which causes blood pressure to rise and regulates the amount of water in the body's cells, and oxytocin, which causes the uterus to contract during childbirth and lactation to begin. (medscape.com)
Meanwhile, the autonomic nervous system stimulates the suprarenal medulla to secrete hormones such as epinephrine into the bloodstream. (medscape.com)
The endocrine system consists of endocrine glands that produce and secrete hormones into the blood stream to reach and act on target cells of specific organs. (medscape.com)
These hormones regulate the body's growth, and are involved in cell to cell communication, control metabolic activity, sleep-wake homeostasis, and altered regulation or dysregulation of adaptive response in various physiologic and pathophysiologic states. (medscape.com)
The endocrine system coordinates functioning between different organs through hormones, which are chemicals released into the bloodstream from specific types of cells within endocrine (ductless) glands. (msdmanuals.com)

An immunocytochemical study was performed on post-mortem hypothalami of GC exposed patients and controls, in which quantification of proAVP, AVP, neurophysin (NP) and oxytocin (OXT) expression were done along with the quantification of PC1, PC2 and 7B2 expression in the paraventricular nucleus, by using a computerized image analysis system. (nel.edu)
Activation of the neuroendocrine response to stressors occurs at the level of the hypothalamic paraventricular nucleus (PVN), which receives varying inputs depending on the nature of the stressor. (nature.com)

The results of this review shows that focus to date has been on genes involved in the regulation of hypothalamic-pituitary-adrenal (HPA) axis and its correlation to subsequent neurobiology, for example, the role of glucocorticoid receptor gene. (biomedcentral.com)
The hypothalamic-pituitary-adrenal (HPA) axis, a neuroendocrine network that controls hormonal responses to internal and external challenges in an organism's environment, exhibits strikingly sex-biased activity. (nature.com)
The ability of all mammals to cope with any environmental or homeostatic challenge (i.e., stressor), or with perceptual threats to homeostasis, relies upon activation of a neuroendocrine signaling cascade called the hypothalamic-pituitary-adrenal (HPA) axis. (nature.com)

AVP-D with an autosomal dominant pattern inheritance is due to a mutation in the prepro-arginine vasopressin ( prepro-AVP2 ) gene, mapped to locus 20p13. (medscape.com)
In attempts to determine whether genetic variations in the oxytocin signaling system contribute to ASD susceptibility, seven recent reports indicated association of common genetic polymorphisms in the OXTR gene with ASD. (biomedcentral.com)
In the cichlid fish species Astatotilapia burtoni , male social status can shift rapidly depending on the environment, causing fast behavioral modifications and a cascade of changes in gene transcription, the brain, and the reproductive system. (biomedcentral.com)
We recently developed a system for translating gene manifestation measurements into diagnostic assessment: the molecular microscope diagnostic system (MMDx) (1). (epf2013.org)

AVP disorders are due either to (1) deficient secretion of antidiuretic hormone (ADH) by the pituitary gland (AVP-D) or to (2) renal tubular unresponsiveness to vasopressin (AVP-R). (medscape.com)

DDAVP in treatment of vasopressin-sensitive diabetes insipidus. (medscape.com)

It is well-established that the neuropeptide arginine vasopressin (Avp) is important to the neural modulation of mammalian behavior. (frontiersin.org)
The results suggest that the antidepressant-like activity of DSS is probably mediated by the modulation of central monoamine neurotransmitter systems and the reduction of oxidative stress. (hindawi.com)

Human and animal investigations of neuroendocrine stress mechanisms that may be involved suggest that (a) chronic social isolation increases the activation of the hypothalamic pituitary adrenocortical axis, and (b) these effects are more dependent on the disruption of a social bond between a significant pair than objective isolation per se. (scienceopen.com)
Two main physiological pathways are involved in converting social-environmental adversity into broad proinflammatory transcriptional modifications that play a role in stress-induced mood disorders: the sympathetic nervous system (SNS), and the HPA axis [ 1 ] . (encyclopedia.pub)

Because most endocrinopathies following traumatic brain injury (TBI) are due to failure at the anterior pituitary level, treatment involves hormonal replacement. (medscape.com)

Their presentations considered (a) the positive influences of water consumption on kidney diseases and urinary tract infection (UTI), (b) human neuroendocrine regulation of water and electrolytes, and (c) low daily water consumption as an epidemiologic risk factor for chronic diseases. (thefactsaboutwater.org)
Regulation of energy balance by leptin involves regulation of several proneuropeptides such as proTRH and proopiomelanocortin. (moam.info)

Nelivaptan (SSR149415) and D-[Leu4-Lys8]-vasopressin are a specific antagonist and agonist for the vasopressin 1b receptor, respectively. (wikipedia.org)

AVP resistance (AVP-R) (nephrogenic diabetes insipidus) arises from defective or absent receptor sites at the cortical collecting duct segment of the nephron (X-linked, vasopressin V2 receptor deficiency, locus Xq28) or defective or absent aquaporin, the protein that transports water at the collecting duct (autosomal recessive, locus 12q13). (medscape.com)

Arginine vasopressin influences several symptoms related to affective disorders including significant memory processes, pain sensitivity, synchronization of biological rhythms and the timing and quality of REM sleep. (wikipedia.org)
It is provisionally suggested that these cytokines may play a role in the provocation or maintenance of depressive disorders, as well as illnesses involving affective components. (aku.edu)
By contrast, inappropriate responsiveness of the stress system may impair growth and development and may account for a number of endocrine, metabolic, autoimmune, and psychiatric disorders. (scienceopen.com)
These findings increase our understanding of the brain circuits and neurotransmitters involved in binge-eating disorder pathology and identify RXFP3 as a therapeutic target for binge-like eating disorders. (jneurosci.org)
The genes involved in signal transduction are major candidates in association studies on affective disorders and responses to antidepressants. (neurotransmitter.net)
Drosophila is an excellent model system for the study of many human neurological disorders and states. (unito.it)
Oxidative stress, which is defined as a disturbance in the balance between the production of reactive oxygen species (ROS) and antioxidant defense systems, has also been shown to play a role in the pathogenesis of neuropsychiatric disorders [ 3 , 4 ]. (hindawi.com)

One aim of the research is to study how environmental information is integrated by the circadian clock to regulate the timing of daily behavioral, physiological and neuroendocrine rhythms. (kent.edu)

The relational factors and neuroendocrine, neurobiological, and genetic mechanisms that may contribute to the association between perceived isolation and mortality are reviewed. (scienceopen.com)
Alterations in the epigenetic signature of genes involved in stress responsivity may represent one of the neurobiological mechanisms. (biomedcentral.com)

V1BR acts as a receptor for vasopressin. (wikipedia.org)

Additional approaches to identify the neuropeptides involved include (i) the peripheral delivery of specific peptide receptor antagonists and antisera to inhibit ACTH responses to nicotine, and (ii) measurement of CRF depletion from the median eminence in colchicine pretreated animals as an index of CRF secretion. (grantome.com)
Whether brainstem catecholaminergic systems mediate these PVN vs hippocampal responses will be evaluated by injecting nicotine into brainstem regions and measuring norepinephrine secretion and the expression of cfos protein. (grantome.com)

Such social behaviors are regulated through oxytocin and vasopressin activation of the oxytocin receptor (OXTR) and vasopressin V1a receptor (AVPR1A) in the brain. (bvsalud.org)
Each involved relatively small sample sizes (57 to 436 families) and, where it was examined, failed to identify association of OXTR polymorphisms with measures of social behavior in individuals with ASD. (biomedcentral.com)
However, the current findings of association in a large independent cohort are consistent with previous results, and the biological plausibility of participation of the oxytocin signaling system in modulating social disruptions characteristic of ASD, suggest that functional polymorphisms of OXTR may contribute to ASD risk in a subset of families. (biomedcentral.com)

In this respect, it has been proposed that signaling molecules (cytokines) released from activated immune cells may serve as messengers (immunotransmitters) stimulating neuroendocrine and central neurotransmitter processes. (aku.edu)
Taken together, after eliminating all sources of contamination, morphine is present in lobster tissues, potentially demonstrating hormonal and neurotransmitter functions that are involved in the animals' stress response. (nel.edu)
In this study, we aim to explore different antidepression mechanisms of DSS by investigating its effect on the monoamine neurotransmitter systems. (hindawi.com)

Primary targets of systemic toxicity were the hematopoietic system, thymolymphatic system and sexual organs. (jaksignaling.com)

Commensal microbiota is involved in stressor-induced immunomodulation, but other biological effects are not yet known. (nature.com)
Further, given that cytokines, such as interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α), elicit neurochemical changes reminiscent of those provoked by stressors, the view has been expressed that the central nervous system (CNS) interprets immune activation much as if it were a stressor. (aku.edu)

Individual hormonal replacement also is indicated, depending on the specific endocrine gland involved. (medscape.com)
Trauma and the endocrine system. (medscape.com)

Appropriate responsiveness of the stress system to stressors is a crucial prerequisite for a sense of well-being, adequate performance of tasks, and positive social interactions. (scienceopen.com)

The lymphatic system is a network of vessels, organs and nodes through which lymphatic fluid (lymph) flows. (relativehealing.com)
These proteins may accumulate locally, causing relatively few symptoms, or widely, involving multiple organs and causing severe multiorgan failure. (msdmanuals.com)

While AVP activates the locus ceruleus-norepinephrine (LC-NE) neuromodulatory system that triggers the behavioral "fight or flight" response from the SNS (mediated by epinephrine and norepinephrine), CRH acts on the pituitary gland, which in response secretes adrenocorticotropic hormone (ACTH) into the bloodstream. (encyclopedia.pub)

Engel JA , Pålsson E, Vallöf D, Jerlhag E. Ghrelin activates the mesolimbic dopamine system via nitric oxide associated mechanisms in the ventral tegmental area. (neurotree.org)

In fact, we demonstrated that an antagonist of ER-β prevents estradiol (E 2 ) inhibition of stimulated VP release from explants of the hypothalamo-neurohypophyseal system (HNS) ( Somponpun and Sladek, 2002 ). (jneurosci.org)
Angiotensin-converting enzyme inhibitors, b-adrenergic receptor blockers and mineralocorticoid receptor antagonists target the inhibition of renin--angiotensin--aldosterone system and adrenergic nervous system and have become a standard component of therapy for heart failure (HF). (docksci.com)

The second aim is to study the effects of ethanol on the circadian timing system. (kent.edu)
The mechanism of cocaine action in the circadian system is not understood. (kent.edu)

However, ghrelin antagonist treatment abolished the FAA in schedule fed fish under 24 h light, suggesting the involvement of the endogenous ghrelin system in this pre-feeding activity. (raf-receptor.com)

essential function in mediating neural progenitor cell function which the Shh signaling pathway is certainly involved with up-regulating miR17-92 cluster appearance. (epf2013.org)

The stress response is subserved by the stress system, which is located both in the central nervous system and the periphery. (scienceopen.com)
The present review examines what is currently known about sex differences in the neuroendocrine response to stress, as well as outstanding questions regarding this sex bias. (nature.com)
The herbal preparation was also effective in improving chronic stress-induced behavioral alterations in rats, which were related to the central arginine vasopressin system [ 14 ]. (hindawi.com)
The long range goal of this research is to understand the interaction(s) between stress-responsive systems within the brain and nicotine, since tobacco is often linked with stress. (grantome.com)
The involvement of the CRH system in gills and skin was investigated in response to infection and in an acute restraint stress paradigm. (silverchair.com)
Thus the peripheral CRH system reacts to infection and stress. (silverchair.com)

Enhanced plasma vasopressin (VP) levels have been associated with the pathophysiology of DKD and CKD. (bvsalud.org)

At this point the initial autonomic nervous system symptoms may reappear (sweating, raised heart rate etc. (daynal.org)
Psychoendocrinology: l-arginine vasopressin and also durability throughout individuals along with key despression symptoms. (uk5099inhibitor.com)

Multidirectional communication likely occurs between the immune, neuroendocrine, autonomicand central nervous systems. (aku.edu)

The result can manifest itself in obvious illnesses such as ulcers, depression, diabetes, trouble with the digestive system or even cardiovascular problems, along with other mental illnesses. (daynal.org)

It links the two by sending and receiving signals from other regions of the nervous system while also controlling the body's "master gland"-the pituitary gland. (pharmaceuticalintelligence.com)

It is generally believed that monoamine neurotransmitters including serotonin (5-HT), noradrenaline (NA), and dopamine (DA) are involved in the pathogenesis of depression, and most antidepressant drugs exert their action by elevating monoamine neurotransmitters concentrations [ 1 , 2 ]. (hindawi.com)
Engel JA , Jerlhag E. Alcohol: mechanisms along the mesolimbic dopamine system. (neurotree.org)

The increase after a reduction of brain water content from salt water loading indicated AVPR1B's role in the neuroendocrine feedback loop in maintaining normal central nervous system fluid balance. (wikipedia.org)
Acquired AVP-D can occur at any age and is usually secondary to a condition damaging the central nervous system. (medscape.com)
Similarly, we present work from group establishing a role for cholinergic synaptic transmission in the central nervous system on behavioral changes that occur during aging. (unito.it)

Like histology, a molecular biopsy assessment system requires thought of the effect of sample adequacy. (epf2013.org)
This required us to develop a system for estimating proportion of cortex inside a core, and to use MF498 this estimate to measure the relationship between proportion of cortex and molecular readings. (epf2013.org)

Acute post-traumatic diabetes insipidus: treatment with continuous intravenous vasopressin. (medscape.com)

Carcinoid tumors develop from neuroendocrine cells in the gastrointestinal tract (90%), pancreas, pulmonary bronchi, and rarely the genitourinary tract. (msdmanuals.com)

Compensatory mechanisms such as neurohormonal systems and the adrenergic nervous system (ANS) play a key role in the pathogenesis of HF [5]. (docksci.com)

It is part of the body's immune system. (relativehealing.com)

These various systems of neuroendocrine regulations make individuals rapidly evaluate and integrate the information related to toxins and pathogen cues, and thus producing appropriate disgust and avoidance behaviors. (psych.ac.cn)

The challenge of translation in social neuroscience: a review of oxytocin, vasopressin, and affiliative behavior. (scienceopen.com)
This review follows the trail of research on oxytocin and vasopressin as an exemplar of one path for exploring the 'dark matter' of social neuroscience. (scienceopen.com)

Anatomy30

Organisms7

Diseases20

Chemicals and Drugs68

Analytical, Diagnostic and Therapeutic Techniques and Equipment8

Psychiatry and Psychology5

Phenomena and Processes27

Disciplines and Occupations1

Information Science3

Health Care1

Corticotropin-releasi3

Neurons9

AVPR1B8

Hypothalamus7

Roles of vasopressin1

Posterior pituitary2

Receptors4

Magnocellular2

Hormones11

Paraventricular nucleus2

Hypothalamic-pituitary-adrenal3

Gene4

Antidiuretic1

DDAVP1

Modulation2

Axis2

Anterior pituitary1

Regulation2

Agonist1

Nephron1

Disorders7

Physiological1

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V1BR1

Secretion2

OXTR3

Neurotransmitter3

Systemic1

Stressor2

Endocrine2

Stressors1

Organs2

ACTH1

Activates1

Inhibition2

Circadian2

Endogenous1

Neural1

Stress6

Pathophysiology1

Symptoms2

Nervous systems1

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Dopamine2

Central3

Molecular2

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Pancreas1

Role in the pathogenesis1

Body's1

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