Neuronal Ceroid-LipofuscinosesCeroidSerine ProteasesThiolester HydrolasesDipeptidyl-Peptidases and Tripeptidyl-PeptidasesNeurodegenerative DiseasesAminopeptidasesBrainLysosomesNeuronsNerve DegenerationDisease Models, AnimalLysosomal Storage Diseases, Nervous SystemLipidosesMolecular ChaperonesHuntington DiseaseLipofuscinMutationNerve Tissue ProteinsEndopeptidasesParkinson DiseaseCathepsin FCystaphosAlzheimer Diseasealpha-SynucleinMembrane ProteinsHeredodegenerative Disorders, Nervous SystemCathepsin DMice, KnockoutMice, Inbred C57BLtau ProteinsLysosomal Storage DiseasesSubdural SpaceAge of OnsetNeuroprotective AgentsPhenotypePedigreeCerebellumEnzyme Replacement TherapyMolecular Sequence DataSpinocerebellar AtaxiasAmyotrophic Lateral SclerosisCells, CulturedMembrane GlycoproteinsChromosomes, Human, Pair 16Dog DiseasesHomozygoteTrinucleotide Repeat ExpansionBipolar DisorderSynucleinsMice, TransgenicMitochondrial Proton-Translocating ATPasesAtrophyInclusion BodiesCell DeathAmyloid beta-PeptidesMental DisordersAmino Acid SequencePrion DiseasesPrionsMicroscopy, Electron, TransmissionCerebral CortexParkinsonian DisordersHippocampusCell LineTauopathiesPeptide HydrolasesMicrogliaProtein TransportGenetic LinkageAnxiety DisordersMood DisordersOxidative StressAtaxiaMitochondriaDNA Mutational AnalysisTrinucleotide RepeatsElectroretinographyMice, Mutant StrainsAstrocytesImmunohistochemistryFriedreich AtaxiaNeurogliaIntranuclear Inclusion BodiesNeurotoxinsGenetic TherapyRats, Sprague-DawleyAllelesBase SequenceNuclear ProteinsPeptidesChromosome MappingCorpus StriatumProton-Translocating ATPasesSignal TransductionPigments, BiologicalMachado-Joseph DiseaseLewy BodiesDiagnostic and Statistical Manual of Mental DisordersPC12 Cells