• Note the mesenchymal protrusions, somites alongside the neural crest. (medscape.com)
  • The cells of each arise from the primitive neural crest, also called the neuroectoderm. (beltina.org)
  • By three weeks of gestational age the neural crest differentiates. (beltina.org)
  • When the neural crest differentiates early in embryonic development, some melanocytes migrate with the cells that form the structures of the brain. (beltina.org)
  • Specific chapters are devoted to various muscle and non-muscle cell lineages involved in heart development, including those of the neural crest, endo- and epicardium, fibroblasts, coronary vessels, and cardiac conduction and lymphatic systems. (cshlpress.com)
  • Background: Neural crest stem cells (NCSCs) are a transient multipotent embryonic cell population that represents a defining characteristic of vertebrates. (monash.edu)
  • The neural crest (NC) gives rise to many derivatives including the neurons and glia of the sensory and autonomic ganglia of the peripheral nervous system, enteric neurons and glia, melanocytes, and the cartilaginous, bony and connective tissue of the craniofacial skeleton, cephalic neuroendocrine organs, and some heart vessels. (monash.edu)
  • Methodology/Principal Findings: We present evidence that neural crest (NC) competence can be acquired very early when human embryonic stem cells (hESCs) are selectively neuralized towards dorsal neuroepithelium in the absence of feeder cells in fully defined conditions. (monash.edu)
  • These early migratory Neural Crest Stem Cells (emNCSCs) uniformly upregulate Sox10 and vimentin, downregulate N-cadherin, and remodel F-actin, consistent with a transition from neuroepithelium to a mesenchymal NC cell. (monash.edu)
  • Along the way, the evolutionary shuffling of pre-existing and novel protein domains to form tenascins, fibronectin and other matrix proteins coincided with the emergence of neural crest, vasculature and the nervous systems that characterise chordates and advanced vertebrates. (biologists.com)
  • Each arch contains similar Arch components derived from endoderm, mesoderm, neural crest and ectoderm. (edu.au)
  • EMT is usually a fundamental process in normal embryonic development, particularly during formation of mesoderm, neural crest formation and heart valve development [10]. (bso14.org)
  • Various embryonic origins contribute to dermis at different regions of the body: dermis of the back skin - dorsal dermis - is derived from somitic dermatome, dermis of the ventral and flank regions is derived from lateral plate mesoderm and the head dermis originates from neural crest cells. (lifemapsc.com)
  • Bhat N, Kwon H, Riley B (2013) A gene network that coordinates preplacodal competence and neural crest specification in zebrafish. (springer.com)
  • [ 4 , 5 ] The paraxial mesoderm in the trunk is transiently organized into approximately 40 segmental tissue blocks alongside the neural tube, known as somites, the cells of which segregate into 2 subpopulations. (medscape.com)
  • The molecules are found on the cell surface, where they facilitate adhesion to neighboring cells or the extracellular matrix, creating stable cell structures and supporting tissue organization. (pharmiweb.com)
  • They play a vital role in tissue development, maintaining tissue integrity, and organizing complex cellular structures. (pharmiweb.com)
  • The exact process of differentiation is not yet understood and although embryonic stem cells can, in principle, provide for all human tissue, scientists are some way from controlling the process. (spiked-online.com)
  • Ex vivo emNCSCs can differentiate into neurons in Ret.k - mouse embryonic gut tissue cultures and transplanted emNCSCs incorporate into NC-derived structures but not CNS tissues in chick embryos. (monash.edu)
  • Many tissue and organs of our body could be infected simply by HCMV. (insulin-receptor.info)
  • ECMs range from pericellular matrices, such as basement membranes, to the grander structures of connective tissue that give organs their shape, and the tendons, cartilage and bones that bestow humans and animals with their form. (biologists.com)
  • Although the overlying neural tissue is partly transparent, and the accompanying glial cells have been shown to act as fibre-optic channels to transport photons directly to the photoreceptors, [7] [8] light scattering does occur. (wikipedia.org)
  • This area, termed the fovea centralis , is avascular (does not have blood vessels), and has minimal neural tissue in front of the photoreceptors, thereby minimizing light scattering. (wikipedia.org)
  • Epithelial organs consist of multiple tissue structures, such as epithelial sheets, blood vessels and nerves, which are spatially organized to achieve optimal physiological functions. (biologists.com)
  • Thyroid hormones influence general tissue growth as well as tubular functions, electrolyte handling and neural input. (avmi.net)
  • To know the main structures derived from components of the pharyngeal arches (groove, pouch and arch connective tissue). (edu.au)
  • 4. Structure of muscle and neural tissue. (pmf.hr)
  • Tissue engineering aims at the development of biological substitutes that can restore, maintain, or improve the functionality of damaged tissue or organs. (bvsalud.org)
  • Tissue engineering is a strategy very used to obtain functional repairing through the development of biological substitutes that can restore, keep or substitute damaged tissues or organs 31 , through the combination of scaffolds biocompatible with live cells and/or bioactive molecules 19 . (bvsalud.org)
  • The use of nanotechnology plays an important role in tissue engineering because the properties that this technology adds to the material, such as the greater surface area and greater roughness, improve the physical-chemical properties which mimic those of the natural tissues and organs 31 . (bvsalud.org)
  • The consistent ultrasound image obtained with the UBM can be used to visualize and guide injection into target organs [ 9 , 10 ], including mouse embryo, to aid in targeted delivery of drugs and viral particles [ 7 , 11 ]. (hindawi.com)
  • The embryo is the earliest stage of development and remains within the egg or reproductive organs of the mother until hatching or birth. (microbiologynote.com)
  • The study of embryo development is known as embryology, which is a branch of biology dedicated to understanding the processes and stages of embryonic growth. (microbiologynote.com)
  • The carefully timed migration of groups of embryonic stem cells produces distinct layers of the embryo that are further shaped and folded into structures such as the neural tube, which gives rise to the spinal cord and brain. (nih.gov)
  • Some anatomical structures in the developing embryo disappear completely or regress substantially once they serve their developmental purpose, remaining only as scar-like vestiges (literally, "footprints") in the mature human. (answersingenesis.org)
  • The first structure observed is the otic placode, on the embryo head surface, that sinks into the mesenchyme to eventually form the inner ear. (edu.au)
  • During the embryonic stage of fetal development, which spans from conception to approximately eight weeks gestation, remarkable changes take place as a single fertilized cell develops into an embryo with distinct organ systems. (fnps-society.org)
  • Targeted neural ablation, but not inhibition of acetylcholine receptors, halts lung branching and causes a reduction in endothelial cells and epithelial and mesenchymal proliferation. (caltech.edu)
  • From this epithelial lining of the primitive gut, organs like the digestive tract, liver, pancreas, and lungs develop. (sheppard-arts.com)
  • Generally speaking, the ectoderm differentiates to form epithelial and neural tissues (spinal cord, peripheral nerves and brain). (sheppard-arts.com)
  • The neural retina consists of several layers of neurons interconnected by synapses and is supported by an outer layer of pigmented epithelial cells. (wikipedia.org)
  • Epithelial organs therefore contain stem cells that are responsible for the continuous cellular remodeling [1]. (bso14.org)
  • The cells can achieve this using unique Isatoribine mechanisms including collective migration [7, 8] or epithelial to mesenchymal transition (EMT) where leading cells at the tip of the branching structures acquire mesenchymal characteristics that facilitate migration into the surrounding stroma [9]. (bso14.org)
  • In early embryonic mammary gland development, Isatoribine the formation of the mammary epithelial placodes in the skin is a critical event. (bso14.org)
  • Structure of epithelial and connective tissues. (pmf.hr)
  • Interestingly, we find that the BAF complex enables access to genes known to be required for the generation of mesoderm- and ectoderm-derived lineages, including muscle, parenchymal cathepsin, neural, and epithelial lineages. (bvsalud.org)
  • In the zebrafish, rprma mRNA is expressed in the olfactory placodes (OP) and olfactory epithelium (OE), rprmb is observed in the tectum opticum (TeO) and trigeminal ganglion (Tg), whereas rprml is found primarily in the telencephalon (Tel). At protein level, RPRM is present in a subset of cells in the OP, and neurons in the OE, TeO, hindbrain and sensory peripheral structures. (frontiersin.org)
  • Neural development involves complex biological machinery to take neural stem cells and turn them into neurons and cortex in the brain. (stjude.org)
  • The experiments with stem cells also revealed that UTX-53BP1 was required for differentiation of the cells into neurons or into brain-like cell structures called cortical organoids. (stjude.org)
  • In that cancer, an epigenetic defect prevents neural stem cells from differentiating into mature neurons, and proliferation of those stem cells produces tumors. (stjude.org)
  • Neural signals from the rods and cones undergo processing by other neurons, whose output takes the form of action potentials in retinal ganglion cells whose axons form the optic nerve. (wikipedia.org)
  • A new study has elucidated the cellular and molecular mechanisms that regulate the balance between the differentiation of neurons and the maintenance of progenitor cells during the construction of the embryonic brain. (sciencemission.com)
  • During embryonic development, coordination takes place between the proliferation of progenitor stem cells responsible for the organ's growth and its differentiation into neurons. (sciencemission.com)
  • A potentially pre-clinical aspect of this thesis is detailed in paper №4 where I describe a robust protocol for the generation of functional mesDA neurons from human embryonic stem cells that are functional in a rat model of PD. (lu.se)
  • Pax-6 acts as a critical gene for the development of eyes and other sensory organs, certain neural and epidermal tissues as well as other homologous structures, usually derived from ectodermal tissues. (biolegend.com)
  • Because the head contains many different structures also review notes on sensory , respiratory , Integumentary ( tooth ), endocrine ( thyroid , parathyroid , pituitary , thymus ) and cleft lip / cleft palate . (edu.au)
  • Bailey AP, Streit A (2005) Sensory organs: making and breaking the pre-placodal region. (springer.com)
  • This structure-the heart-is the first organ to form in vertebrate embryos, and all subsequent life processes depend on its proper function. (cshlpress.com)
  • Moreover, it has recently been shown that mouse and human ES cells can develop into a three-dimentional (3D) optic cup in culture that remarkably resembles the embryonic vertebrate eye 20 , 21 . (nature.com)
  • Baker C, Bronner-Fraser M (2001) Vertebrate cranial placodes I. Embryonic induction. (springer.com)
  • Melanocytes also pigment cells in other organs. (beltina.org)
  • Ig-superfamily CADMs are involved in mediating cell-to-cell adhesion, helping cells stick together and form tissues and organs. (pharmiweb.com)
  • During embryonic development, amorphous cardiac precursor cells are organized into a rhythmically contracting, multi-chambered muscular structure, complete with valves, vessels, and a conduction system. (cshlpress.com)
  • Enhanced cortical neural stem cell identity through short SMAD and WNT inhibition in human cerebral organoids facilitates emergence of outer radial glial cells. (mpg.de)
  • Mouse embryonic stem cells self-organize into trunk-like structures with neural tube and somites. (mpg.de)
  • Embryonic stem cells are derived from early embryos and have the ability to differentiate into any cell type. (spiked-online.com)
  • In his original report, Thompson demonstrated that human embryonic stem cells could be coaxed into developing gut-like structures, bone, cartilage and muscle (1). (spiked-online.com)
  • Scientists anticipate that in the future stem cell lines will provide a virtually unending supply of pancreatic cells for diabetic patients, neuronal cells for patients with neural disorders such as Parkinson's or Alzheimer's disease, and a host of heart cells that may treat a variety of cardiac problems. (spiked-online.com)
  • Blastocytes obtained through nuclear transfers would be used to generate the embryonic stem cells that could be differentiated to specific tissues or organs for transfer to the nuclear donor. (spiked-online.com)
  • Mouse embryonic stem cells are known to be tumorigenic - that is, they can grow uncontrollably and become cancerous. (spiked-online.com)
  • Organs, such as the brain or the heart, are not simply collections of the correct types of cells that are required for their function. (news-medical.net)
  • If these cells are not organized and shaped properly, the organ simply does not function. (news-medical.net)
  • One crucial part of this organization is to bend sheets of connected cells ("epithelia") so that they form a structure that is an integral part of the functional organ. (news-medical.net)
  • Their findings, published in the November/December issue of Mechanisms of Development, reveal a process called "basal constriction" during which cells of the neural tube's epithelium constrict on the outside to actively shape a conserved and crucial early fold in the brain. (news-medical.net)
  • Then, using time-lapse microscopy techniques, postdoctoral scientist Jennifer Gutzman observed the shape changes of individual cells as the neural tube constricted and dilated to form the early embryonic brain. (news-medical.net)
  • We are studying the role that normal chromatin structure plays in gene regulation in hematopoietic cells and how its disruption leads to altered development and cancer. (stanford.edu)
  • Specifically, the UTX-53BP1 interaction executes gene expression programs for neural stem cells to differentiate, or transform for specific duties. (stjude.org)
  • Cells in each germ layer differentiate into tissues and embryonic organs. (sheppard-arts.com)
  • Which structures develop from ectodermal cells? (sheppard-arts.com)
  • Cells in the endoderm layer become the linings of the digestive and respiratory system, and form organs such as the liver and pancreas. (sheppard-arts.com)
  • group of cells that are similar in structure, come from the same embryonic origin, and perform a common function. (sheppard-arts.com)
  • Rb homeostasis is also essential for self-renewal and survival of human embryonic stem cells 10 . (biolegend.com)
  • Two C. elegans cells (blue) migrate from an embryo's surface (top) to its interior (bottom), where the cells will form internal structures. (nih.gov)
  • Like choreographed dancers, cells move in a coordinated manner to help form tissues, organs and limbs during embryonic development. (nih.gov)
  • In one stage of development, certain cells migrate from the embryo's surface to its interior to form internal structures. (nih.gov)
  • In each hemi-segment, a set of neuroblasts produces neural cells by repeated asymmetrical and interiorly directed divisions. (biomedcentral.com)
  • In Euchelicerata and Myriapoda, neurogenesis lacks neural stem cells, featuring instead direct immigration of neural cell groups from fixed sites in the neuroectoderm. (biomedcentral.com)
  • Accordingly, neural stem cells were hitherto assumed to be an evolutionary novelty of the Tetraconata (Hexapoda + crustaceans). (biomedcentral.com)
  • However, in the second phase, the formation of a central invagination in each hemi-neuromere is accompanied by the differentiation of apical neural stem cells. (biomedcentral.com)
  • Directly basal to the neural stem cells, an additional type of intermediate neural precursor is found. (biomedcentral.com)
  • With the currently available data, a common origin of pycnogonid neural stem cells and tetraconate neuroblasts remains unresolved. (biomedcentral.com)
  • Scientists from the University of Cambridge, in collaboration with the Hubrecht Institute in The Netherlands, have developed a new model to study an early stage of human development using human embryonic stem cells. (scitechdaily.com)
  • Published on June 11, 2020, in the journal Nature , the report describes a method of using human embryonic stem cells to generate a three-dimensional assembly of cells, called gastruloids, which differentiate into three layers organized in a manner that resembles the early human body plan. (scitechdaily.com)
  • To make gastruloids in the lab, defined numbers of human embryonic stem cells were placed in small wells, where they formed tight aggregates. (scitechdaily.com)
  • Blue marks DNA, magenta marks neural cells, green marks mesodermal cells. (scitechdaily.com)
  • By looking at which genes were expressed in these human gastruloids at 72 hours of development, the researchers found a clear signature of the event that gives rise to important body structures such as thoracic muscles, bone, and cartilage, but they do not develop brain cells. (scitechdaily.com)
  • It's one of the fundamental stages during embryonic development and concerns the organization and spatial distribution of differentiated cells to form specific structures and eventually complete organs. (ehu.eus)
  • He further clarifies that CartoCell leverages the power of neural networks, specifically an artificial neural network designed to optimize the identification of three-dimensional cells in microscopy images. (ehu.eus)
  • The National Academies of Sciences, Engineering and Medicine have also released guidance for "Human Embryonic Stem Cell Research" (2005 and updated in 2010) which provides no guidance on induced pluripotent stem cells (iPSCs) [ 3 ], and "The emerging field of human neural organoids, transplants, and chimeras" (2021) which didn't include other stem cell-derived tissues and deliberately excluded transplantation of organoids in humans [ 4 ]. (biomedcentral.com)
  • To investigate the microscopic structures of cells, Hay began using electron microscopes in her research about limb regeneration. (asu.edu)
  • That greater magnification enabled Hay to view the structures of cells that are present during limb regeneration. (asu.edu)
  • To understand the multifaced aspects of Parkinson's disease, it may be desirable to expand the complexity of these models, to include different brain regions, vasculature, immune cells as well as additional diverse organ-specific organoids such as gut and intestine. (nature.com)
  • 3. Connective tissues (types of cells and the structure of ground substance, forming of the collagen). (pmf.hr)
  • 5. Immune system (cells, diffuse lymphoid tissues, lymphoid organs). (pmf.hr)
  • Application of various small molecules and recombinant proteins to mouse embryonic stem cells at specific time points in vitro has enabled recapitulation of developmental cues with subsequent formation of inner ear organoids. (springer.com)
  • Chambers S, Fasano C, Papapetrou E (2009) Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. (springer.com)
  • Addition of 400â µM L-proline to self-renewal medium drives naïve mouse embryonic stem cells (ESCs) to early primitive ectoderm-like (EPL) cells - a transcriptionally distinct primed or partially primed pluripotent state. (bvsalud.org)
  • Most cases of this condition result from new (de novo) mutations in the gene that occur during the formation of reproductive cells (eggs or sperm) in an affected individual's parent or in early embryonic development. (medlineplus.gov)
  • Using a neural cortical stem cell model, we find that the epigenetic changes arising as a consequence of alcohol exposure are heavily dependent on the gene under investigation, the dose of alcohol encountered, and that the signatures arising acutely differ significantly from those observed after a 4-day recovery period. (biomedcentral.com)
  • Generation of Mouse Pluripotent Stem Cell-derived Trunk-like Structures: An in vitro Model of Post-implantation Embryogenesis. (mpg.de)
  • After extended infections in vitro of individual embryonic fibroblasts, huge syncytia come in civilizations with regular HCMV intranuclear addition bodies [19]. (insulin-receptor.info)
  • Finally, it remains to be determined whether iPSC can recreate the 3D histo-architecture of the neural retina (NR) in vitro beyond a rudimentary stratification 22 . (nature.com)
  • This section, "The Integumentary System," presents an overview of the structures and functions of the integumentary system, a discussion of dermatological health and disorders, and entries about the health conditions that can affect the skin, hair, and nails. (beltina.org)
  • The foundation of the integumentary system is the skin, which, as the body's largest organ, accounts for 15 percent of the body's weight. (beltina.org)
  • Each stage is critical for proper growth and differentiation of organs and tissues in preparation for life outside the womb. (fnps-society.org)
  • It is characterized by the formation of major organ systems, such as the heart, brain, limbs, and digestive system. (fnps-society.org)
  • The endoderm gives rise to the gut and many internal organs. (sheppard-arts.com)
  • while the endoderm will develop into organs like the lungs and digestive system. (fnps-society.org)
  • UTX opens the chromatin structure to unwrap DNA molecules, allowing their genes to be activated. (stjude.org)
  • Rb is directly involved in heterochromatin formation by maintaining chromatin structure and that of constitutive heterochromatin by stabilizing histone methylation. (biolegend.com)
  • However, while several chemicals can perturb chromatin structure acutely, for many agents (particularly alcohol) it remains unclear if these modifications represent transient responses to exposure or heritable lesions leading to pathology. (biomedcentral.com)
  • Here, we report that mice encountering an acute exposure to alcohol on gestational Day-7 exhibit significant alterations in chromatin structure (histone 3 lysine 9 dimethylation, lysine 9 acetylation, and lysine 27 trimethylation) at Day-17, and that these changes strongly correlate with the development of craniofacial and central nervous system defects. (biomedcentral.com)
  • Unexpectedly, we do not observe a correlation between alcohol-induced changes in chromatin structure and alterations in transcription. (biomedcentral.com)
  • These observations suggest that the immediate and long-term impacts of alcohol exposure on chromatin structure are distinct, and hint at the existence of a possible coordinated epigenetic response to ethanol during development. (biomedcentral.com)
  • Collectively, our results indicate that alcohol-induced modifications to chromatin structure persist beyond the window of exposure, and likely contribute to the development of fetal alcohol syndrome-associated congenital abnormalities. (biomedcentral.com)
  • From studies using a diverse range of model organisms, we now acknowledge that epigenetic modifications to chromatin structure provide a plausible link between environmental exposures and alterations in cellular function leading to pathology [ 1 ]. (biomedcentral.com)
  • Work from a number of independent research groups have demonstrated that ethanol (EtOH) has the capacity to alter chromatin structure, which suggests that epigenetic mechanisms may be relevant to the genesis of birth defects associated with fetal alcohol spectrum disorders (FASDs) [ 2 - 4 ]. (biomedcentral.com)
  • Human embryology, from conception through the embryonic and fetal periods and, finally, birth, has been characterized in detail. (medscape.com)
  • Understanding fetal development has long been a field of interest for researchers and medical professionals alike, as it provides insights into the complex mechanisms behind embryonic and fetal growth. (fnps-society.org)
  • Fetal Stage: Starting around 9 weeks gestation until birth, this stage is marked by rapid growth and refinement of organs and tissues. (fnps-society.org)
  • Ig-superfamily CADMs are involved in a wide range of biological processes and are critical for the development and functioning of various tissues and organs in the body. (pharmiweb.com)
  • This is a hugely exciting new model system, which will allow us to reveal and probe the processes of early human embryonic development in the lab for the first time. (scitechdaily.com)
  • [ 2 ] The development of musculoskeletal structures associated with the trunk of the human body is a multistep process involving differential gene expression as well as cell interactions and cell signaling between precursor tissues. (medscape.com)
  • Denervation of embryonic mouse lung explants reveals that lung branching requires nerves. (caltech.edu)
  • Dermis is formed approximately at E11 of mouse embryonic development. (lifemapsc.com)
  • 1994. Ah receptor in embryonic mouse palate and effects of TCDD on receptor expression. (cdc.gov)
  • The ectoderm gives rise to two distinct lineages, namely, the surface ectoderm and the neural ectoderm. (sheppard-arts.com)
  • One of the first 'great bends' of the brain is called the midbrain-hindbrain boundary constriction and this is essential for normal brain structure," says Sive. (news-medical.net)
  • This volume is therefore a valuable reference for all cell and developmental biologists, geneticists, and cardiologists who are interested in the early development and abnormalities of this complex, vital organ. (cshlpress.com)
  • We are interested in the genes underlying early brain structure, and the connections to devastating birth defects such as anencephaly and hydrocephalus," says Hazel Sive. (news-medical.net)
  • The matrix is essential for early embryonic development and it regulates nearly every facet of cell behaviour. (biologists.com)
  • In vertebrates, the central nervous system is formed from an embryonic structure divided into three vesicles of the brain and the spinal cord. (sciencemission.com)
  • The related structures of upper lip and palate significantly contribute to the majority of face abnormalities. (edu.au)
  • Importantly, a precise temporal description of RPRM protein expression during the development of neuronal structures is still missing. (frontiersin.org)
  • Here, we describe in detail the spatiotemporal expression of three rprm genes ( rprma, rprmb , and rprm l) within distinct anatomical structures in the developing peripheral and central nervous system. (frontiersin.org)
  • Research suggests that impaired PACS1 protein function disrupts normal development of structures in the face, leading to a distinct facial appearance. (medlineplus.gov)
  • On the other hand, morphogens and cell-cell interactions are critical to form a complex, specialized organ such as the mammalian lung. (caltech.edu)
  • [3] This period is called synaptic blooming, and there is a lot of neural growth and the proliferation of dendrites. (physio-pedia.com)
  • Dynamic imaging of Drosophila embryonic tracheal morphogenesis demonstrates that SERCA's principal function is to govern cell migration. (caltech.edu)
  • L1CAM plays a role in neural development, axon guidance, and cell migration. (pharmiweb.com)
  • 12. Female reproductive tract: structure of oviduct and uterus: fertilisation, blastocyst development. (pmf.hr)
  • It includes structures such as the dermal papilla and vascular and neural components that support hair formation and growth. (lifemapsc.com)
  • This period is crucial for the formation and growth of various organ systems that will shape an individual's health throughout their lifespan. (fnps-society.org)
  • Learning how this molecular clutch works could help lay a foundation for the future diagnosis and prevention of spina bifida and other neural tube defects, which are among the most common and serious human birth defects. (nih.gov)
  • The researchers judged the equivalent human embryonic age of the gastruloids by comparing them to the Carnegie Collection of Embryology. (scitechdaily.com)
  • 7. Structure of digestive tract: oesophagus, stomach, small intestine. (pmf.hr)
  • Anatomical structures of great complexity seem to begin as much simpler forms. (answersingenesis.org)
  • No sex Sex The totality of characteristics of reproductive structure, functions, phenotype, and genotype, differentiating the male from the female organism. (lecturio.com)
  • 11. Reproductive system: structure of ovaries and testes. (pmf.hr)
  • We also knew that UTX was required for embryonic development of the brain, heart, bone and other organs. (stjude.org)
  • Removal of inhibitor partially rescues these defects, while simultaneous treatment with both SERCA inhibitor and PKC activator remarkably rescues tracheal and neural development. (caltech.edu)
  • Functional structure of the testis and ovaries. (pmf.hr)
  • 11. Functional structure of the oviducts and uterus. (pmf.hr)