Embryonic Stem CellsCell DifferentiationStem CellsPluripotent Stem CellsCell LineageGene Expression Regulation, DevelopmentalOctamer Transcription Factor-3Embryo, MammalianEmbryoid BodiesCells, CulturedCell LineCell Culture TechniquesHematopoietic Stem CellsHomeodomain ProteinsNeural Stem CellsSOXB1 Transcription FactorsHemangioblastsTranscription FactorsStem Cell TransplantationSignal TransductionTretinoinEndodermCell ProliferationNeuronsMesenchymal Stromal CellsLeukemia Inhibitory FactorGene Expression ProfilingReverse Transcriptase Polymerase Chain ReactionGene Expression RegulationInduced Pluripotent Stem CellsAdult Stem CellsMesodermNeurogenesisFetal ProteinsGene ExpressionRNA, MessengerPhenotypeEpigenesis, GeneticBiological MarkersModels, BiologicalHematopoiesisGreen Fluorescent ProteinsCarcinoma, EmbryonalMyocytes, CardiacDNA-Binding ProteinsPromoter Regions, GeneticMultipotent Stem CellsMice, Inbred C57BLHistonesBone Morphogenetic Protein 4Transcription, GeneticBone Morphogenetic ProteinsBasic Helix-Loop-Helix Transcription FactorsVascular Endothelial Growth Factor Receptor-2ImmunohistochemistryDown-RegulationT-Box Domain ProteinsBase SequenceMolecular Sequence DataTeratomaCell DivisionMice, KnockoutMice, TransgenicOligonucleotide Array Sequence AnalysisRepressor ProteinsFlow CytometryNervous SystemEmbryo ResearchGerm LayersOsteogenesisNerve Tissue ProteinsEmbryonic DevelopmentCoculture TechniquesNestinStem Cell NicheReceptors, NotchEmbryonal Carcinoma Stem CellsBone Marrow CellsAdipogenesisMicroRNAsTime FactorsTissue EngineeringHematopoietic Stem Cell TransplantationNeoplastic Stem CellsGerm CellsRegenerationTotipotent Stem CellsBlotting, WesternCell SurvivalEctodermCell SeparationTransfectionNuclear ProteinsRegenerative MedicineAntigens, DifferentiationEndothelial CellsIn Situ HybridizationRNA InterferenceChimeraGene Targeting