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  • Nodes
  • Nodes are mapped to and positioned on radially distributed linear axes - this mapping is based on network structural properties. (bcgsc.ca)
  • A dynamic contact map defines the edges connecting nodes (amino acids and nucleotides) in the physical network whose overall topology is presented as a network of communities, local substructures that are highly intraconnected, but loosely interconnected. (pnas.org)
  • The contribution of each residue or node to the characteristic path length (CPL), defined as an average of the shortest path length between all pairs of nodes in the network, provides an estimate of the effect of node connectivity on communication pathways in a protein. (pnas.org)
  • These areas represent the nodes of the inferred network. (gatech.edu)
  • Overcome the latency, capacity and energy bottlenecks in network nodes and network interconnects by using optical devices (switches and interconnects). (tue.nl)
  • gene regulat
  • But gene regulatory network architecture can be authenticated only by experimental molecular biology in which the functional meaning of given regulatory sequences is directly determined. (pnas.org)
  • Reengineering genomic control systems: To redesign these most potent of all biological control systems, to both intellectual and practical ends, it is necessary to understand thoroughly the flow of causality in a genomically encoded gene regulatory network. (pnas.org)
  • Through the integration of known TFBS obtained from the literature and experimental studies, we used the CNSs to compile a gene regulatory network in Arabidopsis thaliana containing 40,758 interactions, of which two-thirds act through binding events located in DNase I hypersensitive sites. (plantcell.org)
  • enrichment
  • The course covers methods to process raw data from genome-wide mRNA expression studies (microarrays and RNA-seq) including data normalization, differential expression, clustering, enrichment analysis and network construction. (coursera.org)
  • This network shows significant enrichment toward in vivo targets of known regulators, and its overall quality was confirmed using five different biological validation metrics. (plantcell.org)
  • Optimization
  • Through supply chain network optimization, businesses can address these challenges and realize both bottom- and top-line growth by improving inventory turns and reaping competi- tive advantage from supply chain interactions and transactions. (slideshare.net)
  • Arabidopsis
  • To test for epistasis within an adaptive trait genetic network, we generated and tested 47 Arabidopsis thaliana double mutant combinations for 20 transcription factors, which all influence the accumulation of aliphatic glucosinolates, the defense metabolites that control fitness. (plantcell.org)
  • regulatory network
  • It is most important to determine regulatory network architecture, and this can be done by experimental perturbation followed by measurement of the effects on function of many individual genes. (pnas.org)
  • We outline a computationally inferred model of the regulatory network of Populus leaves, and show how treating genes as interacting, rather than individual, entities identifies new regulators compared to traditional genomics analysis. (diva-portal.org)
  • Approach
  • We propose a new approach to apply network analysis to climate science. (gatech.edu)
  • In this point-of-view paper, we illustrate our latest thinking on a successful supply chain network design that embraces a reliable and flexible approach to supply chain network modeling to resolve thorny business challenges. (slideshare.net)
  • Taking this approach, however, means that solution verification is only possible through real-world evidence, that is, a fully imple- mented supply chain network. (slideshare.net)
  • A configural approach conceptualizes a couple's network as a composite of the shared and separate ties contributed by both partners. (encyclopedia.com)
  • 2001
  • The Blood and Marrow Transplant Clinical Trials Network (BMT CTN) was established in October 2001 to conduct large multi-institutional clinical trials. (emmes.com)
  • molecular
  • Community network analysis derived from molecular dynamics simulations is used to identify and compare the signaling pathways in a bacterial glutamyl-tRNA synthetase (GluRS):tRNA Glu and an archaeal leucyl-tRNA synthetase (LeuRS):tRNA Leu complex. (pnas.org)
  • computational
  • thus, it is essentially a network of analogue computational devices, the functions of which are conditional on their inputs. (pnas.org)
  • Experimental and computational studies of many regulatory complexes support the current view that they possess the intrinsic ability to undergo conformational transitions, conferred by the 3-dimensional network of interresidue interactions ( 4 - 8 ). (pnas.org)
  • complexity
  • Unlike hairballs ( Network visualizations: how to tame the complexity Paweł Widera describes may layout options), hive plots are excellent at managing the visual complexity arising from large number of edges and exposing both trends and outlier patterns in network structure. (bcgsc.ca)
  • researchers
  • The scheme allows researchers from across disciplines and from developing countries and the UK to hold networking events, to forge new links and generate innovative transdisciplinary research ideas to address global challenges. (acmedsci.ac.uk)
  • To add to their understanding of small-network problems, the researchers obtained data from one of the Microsoft Customer Service and Support groups. (microsoft.com)
  • In examining social relationships, some researchers use the terms social network and social support interchangeably (Schonauer et al. (encyclopedia.com)
  • Using an individual perspective, researchers have defined a couple's social ties in terms of the separate personal networks maintained by each partner. (encyclopedia.com)
  • In studying the social context of marital and family life, researchers distinguish between the structure, content, and function of social network relationships. (encyclopedia.com)
  • Researchers who study married couples must also decide if they are interested in the separate networks of marital partners, the degree of overlap between the partners' social ties, or some composite picture of the couple's network relations. (encyclopedia.com)
  • differences
  • Importantly, hive plots are perceptually uniform - differences in hive plots are proportional to differences in underlying networks. (bcgsc.ca)
  • together
  • The phrase networks describes two or more computer systems or electronics devices that are linked together. (webopedia.com)
  • Networks bring together local age sector groups to strengthen the voice of older people and support them to influence decisions on local policy and services. (ageuk.org.uk)
  • collaborative
  • The Childhood Liver Disease Research Network (ChiLDReN) is a collaborative team of doctors, scientists, nurses, research coordinators, medical facilities, patient support organizations and the National Institutes of Health. (childrennetwork.org)
  • Applicants can be from any discipline , and applications should focus on building a collaborative network. (acmedsci.ac.uk)
  • data
  • We're interested in how you apply this network visualization method to your data set- let us know . (bcgsc.ca)
  • Predict network performance by using machine learning to correlate user and application data with actionable insights. (cisco.com)
  • Network connections enable networked computers and devices to communicate with each other and share files, folders, data and more. (webopedia.com)
  • The team presented NetMedic, and its accompanying technical paper, Detailed Diagnosis in Enterprise Networks , during SIGCOMM 2009 , the annual conference of the Association for Computing Machinery's Special Interest Group on Data Communications. (microsoft.com)
  • Software-defined networks hold a lot of potential in today's consolidated data centers. (eweek.com)
  • Solution Challenges Caused by Historical Data The first step that many businesses take when designing new networks, redesigning existing ones or planning additional logistics investments, such as storage capacity extensions, is to analyze historical data. (slideshare.net)
  • There is no one correct definition of a social network, but rather different network delineation strategies yield different data about social relationships. (encyclopedia.com)
  • The different innovative devices are deployed for solving challenges in areas such as Data Center Networks and metro and wide-area networks. (tue.nl)
  • assumptions
  • A lack of detailed quantitative information has generally necessitated a range of simplifying assumptions regarding the structure of contact networks, such as power-law (or scale-free) distributions for the number of contacts and configuration models for generating connections between individuals. (royalsocietypublishing.org)
  • address
  • The hive plot is based on meaningful network properties, which can be selected to address a specific question. (bcgsc.ca)
  • A group of mental health professionals led by the Congressional Men's Health Caucus and Men's Health Network are calling for greater awareness and action to address systemic issues facing men and boy's mental health in the midst of the ongoing national opioid crisis. (menshealthnetwork.org)
  • But Bahl, principal researcher and manager of Microsoft Research Redmond 's Networking Research Group (NRG) was surprised to find that even though small and medium businesses (SMB) constitute a multibillion-dollar market, he could not find any off-the-shelf products to address SMB networking needs. (microsoft.com)
  • design
  • This concept is important, because it holds the key to network design principles. (pnas.org)
  • This strongly impacts how players across industries need to manage inventory and design their supply chain networks. (slideshare.net)
  • edges
  • C) Network edges shown as ribbons creating circularly composited stacked bar plots (a periodic streamgraph). (bcgsc.ca)
  • Links between areas (i.e., the edges of the network) represent non-local dependencies between different regions over a certain time period. (gatech.edu)
  • interactions
  • Although the 2 class I synthetases have remarkably different interactions with their cognate tRNAs, the allosteric networks for charging tRNA with the correct amino acid display considerable similarities. (pnas.org)
  • However, the development of fully mechanistic models of transmission requires a quantitative understanding of social interactions and collective properties of social networks. (royalsocietypublishing.org)
  • practice
  • Age NI supports networks to share information, learning and progress on key issues to bring about positive change to services, policy and practice. (ageuk.org.uk)
  • Research
  • As an integral part of DND i 's model, R&D regional research platforms form part of a broader, positive trend of research networks to maximize worldwide collaborations. (dndi.org)
  • The Academy of Medical Sciences is delighted to be working with the British Academy, the Royal Academy of Engineering and the Royal Society to offer Global Challenges Research Fund (GCRF) Networking Grants, available through the GCRF, which is part of the UK's Official Development Assistance (ODA). (acmedsci.ac.uk)
  • and Jitendra Padhye , Bahl and Mahajan developed NetMedic, a research prototype that addresses management problems inherent in small networks. (microsoft.com)
  • structure
  • The purpose of the hive plot is to establish a new baseline for visualization of large networks - a method that is both general and tunable and useful as a starting point in visually exploring network structure. (bcgsc.ca)
  • The FERN structure is organized to ensure federal and state inter-agency participation and cooperation in the formation, development, and operation of the network. (fernlab.org)
  • The structure of social networks is critical for understanding opportunities and constraints in the development and maintenance of social relationships. (encyclopedia.com)
  • access
  • The remainder can be used to contribute towards travel and subsistence costs, costs associated with networking events, administrative support and access to technical support. (acmedsci.ac.uk)
  • There's a DNA solution for you, whether your priority is gaining 360-degree network visibility or security, or simplifying your wired and wireless access, branch, or WAN networks with software-defined networking. (cisco.com)
  • If you are not a BPS member, but would like to join one or more of our Member Networks, please visit bps.org.uk/join-us for information about how to join the Society and access a great range of benefits. (bps.org.uk)
  • analysis
  • In the 'Topological and Network Evolution Models' module, we provide several lectures about a historical perspective of network analysis in systems biology. (coursera.org)
  • Network analysis provides a powerful, but only marginally explored, framework to validate climate models, quantify uncertainties and investigate teleconnections, assessing their strength, range, and impacts on the climate system. (gatech.edu)
  • management
  • When we first approached the problem," Bahl says, "we looked at enterprise network-management systems, because the NRG has done a lot of work in this space and we believed we could leverage those solutions. (microsoft.com)
  • Join eWeek's James Hilliard as he explores the technology behind software-defined networks and clears up any confusion about SDN with Keith Stewart, senior director of product management at Brocade. (eweek.com)
  • work
  • In a previous post detailing my time with the EQUATOR Network, I spoke about my work on the STrengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement. (equator-network.org)
  • Men's Health Network (MHN) is a national non-profit organization whose mission is to reach men, boys, and their families where they live, work, play, and pray with health awareness and disease prevention messages and tools, screening programs, educational materials, advocacy opportunities, and patient navigation. (menshealthnetwork.org)
  • But it does not work well for a small network, since there could be a single router and a single Web server. (microsoft.com)
  • events
  • The awards provide up to £25,000 over one year to support collaborations between developing countries and the UK and to hold networking events aimed at addressing global challenges. (acmedsci.ac.uk)
  • Support
  • The Food Emergency Response Network (FERN) is composed of four components: the FERN Steering Committee, the FERN National Program Office (NPO), FERN Support Programs, and the FERN Regional Coordination Centers (RCCs). (fernlab.org)
  • level
  • Men's Health Network recommends taking 10 minutes to go through the My Prostate Cancer Coach Risk Tool to better understand your prostate cancer and your risk level, so you and your doctor can make treatment decisions specific to your situation. (menshealthnetwork.org)
  • Catapult your wireless network to the next level. (cisco.com)
  • in large networks, where applications run on dedicated servers, pinpointing problems down to the server level is often enough for an experienced network administrator. (microsoft.com)
  • development
  • What he found-or rather, didn't find-led Bahl and Ratul Mahajan , NRG researcher, to delve into the surprisingly complex issues that challenge the development of diagnostic tools for small networks. (microsoft.com)
  • applications
  • Neural networks applications by Patrick K. Simpson, Institute of Electrical and Electronics Engineers. (google.com)
  • But in a home or SMB network, a single server could run multiple applications, so troubleshooting needs to be more granular and must identify the problem more precisely. (microsoft.com)
  • large
  • In neuroscience , the default mode network ( DMN ), also default network , or default state network , is a large scale brain network of interacting brain regions known to have activity highly correlated with each other and distinct from other networks in the brain. (wikipedia.org)
  • user
  • Any network can be represented as a hive plot ( e.g. gene regulation, protein-protein interaction, internet traffic, user space in a social network, etc). (bcgsc.ca)
  • Another critical reason is that enterprises have more resources, more tools, and experienced, full-time network administrators, whereas the small business or home user will try to manage the network themselves or summon part-time help. (microsoft.com)