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  • fibers
  • A new material made of carbon nanotubes supports the growth of nerve fibers, bridging segregated neural explants and providing a functional re-connection. (phys.org)
  • In those conditions, without any scaffolds reconstructing the space between the two explants, we observed growth of nerve fibers that extended in straight bundles in any direction, but not necessarily toward the other tissue. (phys.org)
  • If we insert a small piece of the carbon sponge into the space between the two, however, we see dense growth of nerve fibers that fill the structure and intertwine with the other sample. (phys.org)
  • A complex study, lasting several years and involving work groups with specialties in various fields, has shown that a new material (a three-dimensional sponge made of carbon nanotubes) supports the growth of nerve fibers, bridging segregated neural explants and providing a functional re-connection. (sissa.it)
  • The sympathetic nerve fibers arise from the thoracolumbar lateral gray matter of the spinal cord (T1-L2). (lecturio.com)
  • Microscopic Slide Examination: Nervous Tissue Worksheet and Photos Insert the photos of the spinal cord smear and teased myelinated nerve fibers (at 100X and 400X magnification) in the boxes. (coursehero.com)
  • pseudounipolar sensory neuron in a dorsal root (spinal) ganglion CNS PNS sensory input Somatic motor neurons of the spinal cord also have components in the CNS and PNS, but they are multipolar Motor output: axon travels through peripheral nerve to reach target muscle An example of sensory input: the muscle spindle Specialized skeletal muscle fibers enclosed within a spindle-shaped capsule. (slidegur.com)
  • Regenerative sieve electrodes offer a unique alternative to such devices, achieving a highly stable, selective electrical interface with independent groups of regenerated nerve fibers integrated into the electrode. (wustl.edu)
  • The brain and spinal cord communicates with what is occurring in the internal organs and limbs by nerve fibers where are like electrical wires with insulation (myelin) and the "copper" (axon). (healthtap.com)
  • It contains over 1.2 million fibers as well as supporting elements.A truly amazing nerve. (healthtap.com)
  • DALLAS - November 7, 2016 - TissueGen┬« Inc., developer of ELUTE┬« fiber, enables controlled sustained delivery of sensitive pharmaceuticals and biologics from biodegradable fibers for advanced drug delivery, nerve regeneration, and tissue engineering. (textileworld.com)
  • sciatic nerve
  • The accumulation of free acrylamide in the distal region of the sciatic nerve was studied in male Sprague-Dawley-rats injected daily (5 days per week) with 35mg/kg acrylamide for 0 to 4 weeks. (cdc.gov)
  • In vivo testing in rat sciatic nerve further validated the ability of chronically-implanted regenerative sieve electrodes to facilitate FES of regenerated motor axons and selective recruitment of distal musculature. (wustl.edu)
  • scar tissue
  • These materials could be useful for covering electrodes used for treating movement disorders like Parkinson's because they are well accepted by tissue, while the implants being used today become less effective over time because of scar tissue. (phys.org)
  • distal
  • A working procedure was demonstrated for the analysis of plasma spiked with acrylamide (79061) and for the detection of acrylamide in the proximal and distal regions of excised sciatic nerves from rats administered acrylamide subcutaneously. (cdc.gov)
  • However, existing microelectrodes designed to stimulate peripheral nerve are unable to provide the type of stable, selective interface required to achieve near-physiologic control of peripheral motor axons and distal musculature. (wustl.edu)
  • This hypothesis was systematically tested through a series of experiments examining the ability of both micro-sieve electrodes and macro-sieve electrodes to achieve a stable interface with peripheral nerve tissue, electrically activate small groups of regenerated motor axons, and selectively recruit motor units present in multiple distal muscles. (wustl.edu)
  • 16. The apparatus of claim 1, wherein the manifold is positioned on the distal side of the nerve conduit relative to the tissue site. (patentsencyclopedia.com)
  • Skeletal
  • I guess, the term "satellite cells" has been mentioned so often in the course of the past couple of weeks that it actually would not be necessary to tell you (once again) that these myogenic precursor cells are a necessary prerequisite for the repair and long-term growth of your pecs, legs, back, biceps, triceps, delts and the rest of the skeletal muscle tissue in your body. (blogspot.com)
  • neural
  • These findings further highlight the clinical potential of implantable microelectrodes capable of intimately integrating into host neural tissue. (wustl.edu)
  • cells
  • Neuroblastoma is a cancer that arises in immature nerve cells and affects mostly infants and children. (rxpgnews.com)
  • At lower frame are astrocytes, non-conducting star-shaped cells which supply nerve cells with nutrients and may store nerve information. (sciencephoto.com)
  • The therapy uses a population of cells derived from human embryonic stem cells containing progenitor cells that support nerve cells and can potentially make poorly functioning nerves function better. (rush.edu)
  • Laminin is a glycoprotein naturally occurring in nerves and it plays a significant role towards the migration of nerve cells and axonal outgrowth. (nus.edu.sg)
  • 14. The apparatus of claim 1, wherein the nerve conduit comprises pores that are sufficiently small to exclude the entry of cells into the luminal space. (patentsencyclopedia.com)
  • have made quite some progress in "producing" and "reprogramming" stem cells from all sorts of human and animal tissue . (blogspot.com)
  • Apparatus
  • Provided is an apparatus that includes a nerve conduit, a manifold and a support structure for providing a reduced pressure. (patentsencyclopedia.com)
  • 3. The apparatus of claim 2, wherein the nerve conduit comprises a material generally impermeable to fluids from tissue surrounding the nerve conduit. (patentsencyclopedia.com)
  • 8. The apparatus of claim 1, wherein the defect is a severed, partially severed, pinched, or degenerated nerve. (patentsencyclopedia.com)
  • 10. The apparatus of claim 1, wherein the second end portion of the support structure provides a detachable coupling of the manifold to the nerve conduit. (patentsencyclopedia.com)
  • 11. The apparatus of claim 1, wherein the second end portion of the support structure comprises an adhesive for coupling the manifold and the nerve conduit. (patentsencyclopedia.com)
  • 13. The apparatus of claim 1, wherein the manifold serves as a scaffold that facilitates tissue growth or regrowth. (patentsencyclopedia.com)
  • regenerative
  • In summary, the present body of work provides initial evidence of the utility of regenerative electrodes as a means of selectively interfacing peripheral nerve tissue for the purpose of restoring muscle activation and motor control. (wustl.edu)
  • repair
  • Initial studies conducted by Christine Radtke, new Professor for Plastic and Reconstructive Surgery at MedUni Vienna/Vienna General Hospital, have shown in an animal model that the threads have great potential for nerve and tissue repair. (meduniwien.ac.at)
  • Additionally provided is a method that includes implanting the above nerve conduit, manifold and support structure at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulating repair or regrowth of nerve tissue. (patentsencyclopedia.com)
  • Despite advances in microsurgical techniques and a progressive understanding of pathophysiological mechanisms, peripheral nerve repair continues to be a major clinical challenge. (hindawi.com)
  • However, the degree of reinnervation is dependent on many factors such as the severity of injury, interstump gap length, alignment of nerve stumps, anatomical location of injury, delay before surgical intervention, and type of repair procedure applied [ 9 ]. (hindawi.com)
  • The clinical gold standard repair strategy for repairing large gaps in transected peripheral nerves is the nerve autograft. (hindawi.com)
  • In particular, the use of tissue engineering to construct artificial tissue that mimics the nerve autograft provides a potentially innovative solution for peripheral nerve repair. (hindawi.com)
  • Regarding the nerve tissue, only a surgical repair of a 35 mm-long nerve defect in the median nerve of the right arm at elbow level with an artificial nerve graft, comprising an outer microporous conduit of CHI and internal oriented filaments of poly(glycolic acid), was reported. (imtlucca.it)
  • conduit
  • Also provided is a system that includes a source of reduced pressure, a nerve conduit, a manifold, a support structure and a conduit for providing fluid communication between the manifold support and the source of reduced pressure. (patentsencyclopedia.com)
  • and a first support structure having a generally tubular shape for enclosing the support surface, a first end portion for coupling the first end wall surface to the reduced-pressure source, and a second end portion for coupling the manifold to the nerve conduit in a generally radial direction with respect to the luminal wall. (patentsencyclopedia.com)
  • Clinical
  • Since nerve biopsies are not routinely feasible for patients undergoing chemotherapy for early breast cancer, this promising biomarker strategy is compatible with current clinical workflow. (physiciansweekly.com)
  • grew
  • What is different about this research is that we also were able to look at specific points in time to see where the virus grew in the tissues, not just the blood, so we can identify and target the reservoirs where the virus hides," Streblow explained in a university news release. (hon.ch)
  • found
  • Archived mammary tissue specimen blocks of breast cancer patients who received weekly paclitaxel in a single centre were retrieved and NDRG1 immunohistochemistry was performed on normal nerve tissue found within the sample. (physiciansweekly.com)
  • method
  • This method is not ideal because of donor site morbidity, the requirement for additional surgery, and limited donor tissue availability. (hindawi.com)
  • material
  • It was Maurizio Prato's intuition, however, that pushed them to investigate the possibility of applying such material to nerve tissue. (phys.org)