Nerve fibers and nerve. Medical search. Frequent questions

Nerve fibers conduct nerve impulses to and from the central nervous system. (usda.gov)
The structure and composition of the sciatic nerve is made of smaller elements that help conduct sensory and motor impulses to the lower part of the body below the hip. (spine-health.com)
Sensory fibers -help conduct impulses, resulting in sensations that cannot be seen, but felt (such as touch and pain). (spine-health.com)
When we have accurate measurements of the size and degree of myelination of nerve fiber types, we can better predict physiologic properties, such as how fast the nerve fiber impulses travel and how easy or difficult it is to activate them," says Dr. Havton. (mountsinai.org)
covered by a fatty substance called myelin that promotes the rapid transmission of nerve impulses. (medlineplus.gov)
The optics of the eye create a focused two-dimensional image of the visual world on the retina, which then processes that image within the retina and sends nerve impulses along the optic nerve to the visual cortex to create visual perception . (wikipedia.org)
Light striking the retina initiates a cascade of chemical and electrical events that ultimately trigger nerve impulses that are sent to various visual centres of the brain through the fibres of the optic nerve . (wikipedia.org)
This myelin sheath allows electrical impulses to transmit quickly and efficiently along the nerve cells. (github.io)
These are small myelinated (A δ ) and unmyelinated (C) fibers that convey impulses from bladder wall receptors. (jneurosci.org)
It combines selective nerve and muscle transfers, elective amputation, and replacement with an advanced robotic prosthesis (using sensors that respond to electrical impulses in the muscles). (sciencedaily.com)
Much like the insulation around an electrical wire, the myelin sheath enables nerve signals (electrical impulses) to be conducted along the nerve fiber with speed and accuracy. (msdmanuals.com)
When the myelin sheath is damaged (called demyelination), nerves do not conduct electrical impulses normally. (msdmanuals.com)

This is due to the number of synapses formed by the preganglionic fibers with ganglionic neurons. (wikipedia.org)
Nerve fibers form connections between the nerve cells (neurons) of the cerebral cortex and serve to link various regions of the nervous system with each other allowing for the exchange of neural information. (charite.de)
The nerve fibers of Satb2 producing neurons also produce Unc5C, which is repelled by netrin1. (charite.de)
Neural signals from the rods and cones undergo processing by other neurons, whose output takes the form of action potentials in retinal ganglion cells whose axons form the optic nerve. (wikipedia.org)

The AXONS of the myelinated nerve fibers are completely encased in a MYELIN SHEATH. (wakehealth.edu)
What do you call the neuroglial cells that form myelin sheaths around the nerve fibers of the CENTRAL NERVOUS SYSTEM? (github.io)
Schwann cells make myelin in the peripheral nervous system (PNS: nerves) and oligodendrocytes in the central nervous system (CNS: brain and spinal cord). (github.io)
Myelin is an insulating layer, or sheath that forms around nerves, including those in the brain and spinal cord. (github.io)
This is not surprising given the strong evidence for interaction between myelin and axon gene expression in development and after experimental nerve lesions. (medscape.com)
Overview of Demyelinating Disorders Most nerve fibers inside and outside the brain are wrapped with many layers of tissue composed of a fat (lipoprotein) called myelin. (msdmanuals.com)
Demyelination is the destruction of the tissues that wrap around nerves, called the myelin sheath. (msdmanuals.com)
The autoimmune reaction results in inflammation, which damages the myelin sheath and the nerve fiber under it. (msdmanuals.com)

In normal eyes, the retinal nerve fiber layer (RNFL) is usually best visible in the inferior temporal part of the fundus, followed by the superior temporal region, the nasal superior region and the nasal inferior region. (nih.gov)
With all optic nerve diseases, the visibility of the RNFL is decreased in addition to the age-related loss, in a diffuse and/or a localized manner. (nih.gov)
The purpose of this study was to compare high-pass resolution perimetry (HRP) test results with clinical optic disc measurements and semi-quantitative retinal nerve fiber layer (RNFL) estimates. (nih.gov)
IOVS 2005) of retinal nerve fiber layer (RNFL) thickness estimates obtained from Optical Coherence Tomograph (OCT) for differentiating healthy and early glaucomatous eyes. (arvojournals.org)
The association between cognitive functioning and retinal nerve fiber layer (RNFL) thickness was assessed in a large, population-based sample. (ox.ac.uk)
PURPOSE: To evaluate the parameters of optic nerve head (ONH) and retinal nerve fiber layer (RNFL) in patients with large cup/disc ratio (CDR) and normal neuroretinal rim configuration who have normal perimetry (physiologic large cups, LC) and to compare these parameters with those of the normal and early glaucoma patients. (elsevierpure.com)
RESULTS: Significant differences between LC and glaucomatous eyes (GE) were found in parameters indicating loss of nerve fibers, such as rim area, rim volume, and mean RNFL thickness. (elsevierpure.com)
Background: Measurement of retinal nerve fiber layer (RNFL) thickness in multiple sclerosis (MS) is gaining increasing attention. (elsevierpure.com)
Objectives: To explore the relationship between RNFL thickness as measured by optical coherence tomography (OCT) and scanning laser polarimetry with variable corneal compensation (GDx), and conventional and non-conventional optic nerve and brain MRI measures. (elsevierpure.com)
Results: LCLA, RNFL-OCT and optic nerve radius measures showed more robust differences between NC and MS patients, and between MS patients with affected and unaffected eyes. (elsevierpure.com)
Unique additive variance regression models showed that both brain and optic nerve MRI measures independently accounted for about 50% of the variance in LCLA and RNFL thickness. (elsevierpure.com)
Conclusions: Measurement of RNFL thickness and radius of the optic nerve should be preferred to the other optic nerve MRI measures in clinical studies. (elsevierpure.com)
Racial differences in the anatomy of the optic nerve head (ONH), such as larger optic discs and disc area, deeper cups, variation in lamina cribrosa position, and thicker overall retinal nerve fiber layer (RNFL) and peripapillary choroid thicknesses in AD individuals, have also been previously described. (cdc.gov)
The purpose of this study is to determine if BMO-MRW varies with race, specifically across people of AD and ED, and how BMO-MRW relates to retinal nerve fiber layer (RNFL) thickness. (cdc.gov)

Retinal Nerve Fiber Layer Thickness in Patients With Obstruc. (lww.com)
Average and superior quadrant retinal nerve fiber layer thickness (RNFLT) was lower in the more severe obstructive sleep apnea (OSA) group and inversely associated with apnea-hypopnea index (AHI). (lww.com)
Epidermal Nerve Fiber Thickness Testing (ENFTT) is an all of the greater as of past due created neuropathology check wherein a punch pores and skin biopsy is taken to differentiate little fiber neuropathies through investigating the nerve strands of the pores and skin. (scitechnol.com)
Our study aims to create a normative database of the peripapillary fibers thickness for children aged from 3 to 15 years, using a spectral-domain OCT: the Spectralis TM. (scitechnol.com)
The thickness of peripapillary fibers was measured according to the age, the side of the eye, the peripapillary area and the spherical equivalent. (scitechnol.com)
According to this study, the side, the gender and the age have no significative influence on the fibers thickness. (scitechnol.com)
The duplication of studies on this subject would provide a pediatric database grouping values on the peripapillary optical fiber thickness. (scitechnol.com)
The GDx is a tool that uses laser to determine the thickness of the nerve fiber layer. (oakvilleeye.com)
The GDx uses a type of scanning laser polarimeter to measure the thickness of the nerve fiber layer. (oakvilleeye.com)
The thickness of the nerve fiber layer is then compared with the nerve fiber layer of normal eyes. (oakvilleeye.com)
To calculate the anterior lamina cribrosa depth (ALCD) and lamina cribrosa thickness (LCT) in primary open angle glaucoma (POAG) patients and controls and to correlate lamina cribrosa (LC) parameters to retinal nerve fiber layer thickness (RNFLT) and visual field (VF) defects. (org.pk)
Association of cognitive functioning with retinal nerve fiber layer thickness. (ox.ac.uk)
To evaluate the changes in intraocular pressure (IOP), corneal thickness (CT), and retinal nerve fiber layer thickness (RNFLT) in patients with hypothyroidism before and after treatment. (gazi.edu.tr)
Optic nerve head topographic measurements and retinal nerve fiber layer thickness in physiologic large cups. (elsevierpure.com)

This suggests that HRP is a useful psychophysical test to assess optic nerve integrity in glaucoma. (nih.gov)
Although these tests are extremely important in the treatment and management of glaucoma, it would be helpful to measure or test early what damage glaucoma can cause to the nerve fiber layer in the back of the eye. (oakvilleeye.com)
In many patients with glaucoma, considerable nerve fiber layer damage may have already occurred by the time any vision loss is noticed. (oakvilleeye.com)
The GDx maps the nerve fibers and compares them to a database of healthy, glaucoma-free patients. (oakvilleeye.com)
A thinning of the fibers indicates glaucoma. (oakvilleeye.com)
While nerve fiber analysis as a standalone test does not make for a definitive diagnosis of glaucoma, it does provide your doctor with data that will add to your overall case so that better decisions may be made regarding your treatment. (oakvilleeye.com)
Naz AS, Qamar A, Sama-Ul-Haque, Zaman Y, Faheem F. Association of lamina cribrosa morphometry with retinal nerve fiber layer loss and visual field defects in primary open angle glaucoma. (org.pk)

The Epidermal Nerve Fiber Density (ENFD) check is the great goal device for documenting small fiber peripheral neuropathy through quantifying the terminal branches of peripheral nerves in the epidermis [ 1 ]. (scitechnol.com)
Epidermal nerve fiber density is a check which permits for the prognosis of small fiber peripheral neuropathy in a goal manner, primarily based totally at the evaluation of a not unusual place punch of pores and skin [ 2 ]. (scitechnol.com)
22. What is an Epidermal Nerve Fiber Density Biopsy? (peripheralneuropathyhelpcenter.com)
An epidermal nerve fiber density biopsy, also called an intraepidermal nerve fiber density biopsy or a nerve density skin biopsy, is a test that is performed by a physician to determine if you have a small fiber neuropathy. (peripheralneuropathyhelpcenter.com)

Segmentation of axons in light and electron micrographs allows for quantitative high-resolution analysis of nerve fiber tissues-but varied axonal angles result in an overestimation of fiber sizes. (mountsinai.org)
The nerve fiber layer consists of millions of individual fibers called "axons" that surround the optic nerve and spread out over your retina. (oakvilleeye.com)
In this condition, the small fibers that extend from the nociceptors through which pain signals are transmitted (axons) degenerate over time. (medlineplus.gov)

Considering its great importance in the assessment of optic nerve anomalies and diseases and taking into account the feasibility of its ophthalmoscopic evaluation using green light, the retinal nerve fiber layer should be examined during any routine ophthalmoscopy. (nih.gov)
Small fiber neuropathy is a sickness characterized through faded nerve fiber density with inside the epidermis (outer layer) of the pores and skin, ensuing in painful symptoms, generally with inside the extremities, which cannot often end up disabling. (scitechnol.com)
Myelinated retinal nerve fiber layer is rare. (panafrican-med-journal.com)
Fundus examination of the left eye was without abnormalities (B). Scan of Spectral Domain Optical Coherence Tomography (SD-OCT) showed isolated hyper reflectivity of the fiber optic layer, an abnormality of the vitreoretinal interface with posterior shadow cone effect (C). (panafrican-med-journal.com)
Few anecdotal reports have documented new onset and progression of myelination of the retinal nerve fiber layer. (huji.ac.il)
The authors report the unusual onset and progression of acquired myelination of the retinal nerve fiber layer in two children, following the diagnosis of presumed idiopathic intracranial hypertension. (huji.ac.il)
The nosologic relationship between myelination of the retinal nerve fiber layer and idiopathic intracranial hypertension is unclear and requires elucidation by further studies. (huji.ac.il)

Sympathetic preganglionic fibers tend to be shorter than parasympathetic preganglionic fibers because sympathetic ganglia are often closer to the spinal cord than are the parasympathetic ganglia. (wikipedia.org)
The dorsal and ventral roots branch off from the spinal cord and merge together to form a single spinal nerve. (spine-health.com)
At the level of each spinal segment, two individual "roots" (bundles of nerve fibers) branch off the spinal cord and merge right before it enters the intervertebral foramen as a single nerve root. (spine-health.com)
A small group of nerve fibers derived from the back (posterior end) of the spinal cord. (spine-health.com)
A comparatively larger group of nerve fibers derived from the front (anterior end) of the spinal cord. (spine-health.com)
The nerve fibers that carry pain signals to the brain are overly activated, and some of the small, unmyelinated nerves in the skin and the eyes that carry sensory information to the spinal cord and brain are damaged in some patients. (omf.ngo)
Small fiber neuropathy is considered a form of peripheral neuropathy because it affects the peripheral nervous system, which connects the brain and spinal cord to muscles and to cells that detect sensations such as touch, smell, and pain. (medlineplus.gov)
The NaV1.7 and NaV1.8 sodium channels are found in nerve cells called nociceptors that transmit pain signals to the spinal cord and brain. (medlineplus.gov)
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) , which includes the brain , spinal cord , and optic nerve . (healthline.com)
of nerves in the brain and spinal cord. (msdmanuals.com)

Watch this Sciatic Nerve Anatomy Video in our Video Center. (spine-health.com)
The complex anatomy of the sciatic nerve means that symptoms of sciatica vary depending on where this irritation occurs. (spine-health.com)
The nerve root is short, at times measuring just 1 mm in length 2 Bogduk N. Clinical and Radiological Anatomy of the Lumbar Spine E-Book. (spine-health.com)

For instance, the control of the limbs in people with motor deficiencies needs information about the muscle lengths and speeds that can be extracted from electroneurograms (ENG) carried on afferent peripheral nerves. (cnrs.fr)
These data strongly suggest a major sensory role for urothelially released ATP acting via P2X 3 receptors on a subpopulation of pelvic afferent fibers. (jneurosci.org)
The storage and periodic evacuation of urine by the bladder is regulated by a complex neural control system that consists of the CNS and the afferent and efferent spinal nerves. (jneurosci.org)
It contains somatic and visceral afferent fibers, as well as general and special visceral efferent fibers. (medscape.com)

Neuropathology ought now no longer be flawed for neuropathy, which alludes to troubles of the real nerves (for the maximum component with inside the fringe sensory gadget) in place of the tissues. (scitechnol.com)
If the density of the small nerve fibers in the skin is less than normal the diagnosis of small fiber neuropathy may be made. (peripheralneuropathyhelpcenter.com)
21. What is Small Fiber Neuropathy? (peripheralneuropathyhelpcenter.com)
Small fiber neuropathy is a condition characterized by severe pain attacks that typically begin in the feet or hands. (medlineplus.gov)
The signs and symptoms of small fiber neuropathy usually begin in adolescence to mid-adulthood. (medlineplus.gov)
Individuals with small fiber neuropathy cannot feel pain that is concentrated in a very small area, such as the prick of a pin. (medlineplus.gov)
The prevalence of small fiber neuropathy is unknown. (medlineplus.gov)
Mutations in the SCN9A or SCN10A gene can cause small fiber neuropathy. (medlineplus.gov)
The SCN9A gene mutations that cause small fiber neuropathy result in NaV1.7 sodium channels that do not close completely when the channel is turned off. (medlineplus.gov)
Diabetes mellitus and impaired glucose tolerance are the most common diseases that lead to this disorder, with 6 to 50 percent of diabetics or pre-diabetics developing small fiber neuropathy. (medlineplus.gov)
Small fiber neuropathy is inherited in an autosomal dominant pattern, which means one copy of the altered SCN9A gene or SCN10A gene in each cell is sufficient to cause the disorder. (medlineplus.gov)
When the genetic cause of small fiber neuropathy is unknown or when the condition is caused by another disorder, the inheritance pattern is unclear. (medlineplus.gov)
In the late 1960s, neurophysiologic testing allowed the classification of CMT into 2 groups, one with slow nerve conduction velocities and histologic features of a hypertrophic demyelinating neuropathy (hereditary motor and sensory neuropathy type 1 or CMT1) and another with relatively normal velocities and axonal and neuronal degeneration (hereditary motor and sensory neuropathy type 2 or CMT2). (medscape.com)
Subjects were examined for neuropathy, and nerve conduction was measured at the peroneal motor nerve, sural sensory nerve, and ulnar sensory and motor nerves. (cdc.gov)
Only one subject, a diabetic, had both abnormal nerve velocities and signs of neuropathy. (cdc.gov)
The authors conclude that nerve conduction velocities are insensitive in screening for subclinical neuropathy in subjects exposed to inorganic arsenic. (cdc.gov)

Which Cranial nerve(s) come from the midbrain? (proprofs.com)
Cranial nerve V comes from what part of the brain stem? (proprofs.com)
Cranial nerve V, also known as the trigeminal nerve, originates from the pons, which is a part of the brainstem. (proprofs.com)
Cranial nerve 9, also known as the Glossopharyngeal nerve, controls functions like taste and swallowing. (proprofs.com)
Among the options given, the only cranial nerve that exits from this location is the third cranial nerve, also known as the oculomotor nerve. (proprofs.com)
The vagus nerve is the longest cranial nerve. (medscape.com)
The vagus nerve is joined by the cranial root of the accessory nerve (cranial nerve XI), just below the inferior ganglion. (medscape.com)

The biopsy is sent to a pathology lab where it is treated with a special stain and the small nerve fibers in the skin are counted. (peripheralneuropathyhelpcenter.com)

Throughout the years, in the absence of ancillary or diagnostic tools, many descriptive phrases, clichés, or analogies have been used to describe the eye, such as "the eye is the window to the soul," the "eye works like a camera," and "the eye is the only structure that allows us to physically see blood vessels and nerve fibers. (medscape.com)
blood vessels, nerve fibers, and connective tissue. (cdc.gov)

In the autonomic nervous system, fibers from the CNS to the ganglion are known as preganglionic fibers. (wikipedia.org)

Myelinated nerve fibers are present in somatic and autonomic nerves. (wakehealth.edu)

All preganglionic fibers, whether they are in the sympathetic division or in the parasympathetic division, are cholinergic (that is, these fibers use acetylcholine as their neurotransmitter) and they are myelinated. (wikipedia.org)

A new study reports prediabetes may be more damaging to motor nerves than previously believed. (neurosciencenews.com)

Their NEURAL CONDUCTION rates are faster than those of the unmyelinated nerve fibers (NERVE FIBERS, UNMYELINATED). (wakehealth.edu)
SAE could play a particularly important role in the rapidly emerging field of neuromodulation, which provides electrical stimulation to the brain or peripheral nerves through the activation of certain fiber systems to modulate abnormal neural pathways. (mountsinai.org)
The correction for fiber dispersion angle markedly reduces the number of outliers and data scatter, allowing for enhanced anatomical mapping as well as improved predictions of functional properties in translational studies of neural repair and nerve regeneration. (mountsinai.org)
Burnstock (1999) recently put forward a hypothesis about purinergic mechanosensory transduction that proposed that in hollow organs, including the ureter and bladder, distension causes release of ATP from epithelial cells lining these organs and that ATP can then activate P2X 3 receptors on subepithelial sensory nerve terminals to evoke neural discharge. (jneurosci.org)
The scientific advance here was that we were able to create and extract new neural signals via nerve transfers amplified by muscle transplantation. (sciencedaily.com)

The anterior and posterior gastric nerves are then formed from the esophageal plexus. (medscape.com)
Similarly, the posterior gastric nerve is formed mainly from the right vagus but contains fibers from the left vagus nerve. (medscape.com)

Cranial nerves IV (trochlear nerve) and III (oculomotor nerve) originate from the midbrain. (proprofs.com)
Where do Cranial nerves 9,10 & 11 originate from? (proprofs.com)
Cranial nerves 9, 10, and 11 originate from the Medulla. (proprofs.com)
Brachial plexus injuries occur when the nerves of the brachial plexus -- the network of nerves that originate in the neck region and branch off to form the nerves that control movement and sensation in the upper limbs, including the shoulder, arm, forearm, and hand -- are damaged. (sciencedaily.com)

After a 7 week treatment period, 12-week-old db/db-vehicle, db/+ -vehicle and db/db-EQ treated animals were evaluated by nerve conduction, paw withdrawal against a hotplate, and fiber density in hindlimb footpads. (nature.com)
SP nerve fiber density was measured in nasal mucosal tissues using immunocytochemistry. (cdc.gov)
SP nerve fiber density (% nerve fiber area) was significantly increased 12, 24 and 48 hrs after TOI exposure. (cdc.gov)

Radiculopathy originating from the sciatic nerve may be felt in clearly outlined (and often overlapping) areas of the thigh and leg, which are responsible for the distinctive symptom patterns associated with sciatica and tend to also help physicians identify the level of the spinal segment(s) that are involved in causing the symptoms. (spine-health.com)
The sciatic nerve is the longest and largest nerve in the human body, running from the lower back through the back of the leg, and down to the toes. (spine-health.com)
The sciatic nerve starts as a collection of nerve fibers in the lower spine. (spine-health.com)
The sciatic nerve is about as thick as a man's thumb at its largest point. (spine-health.com)
The sciatic nerve travels through an opening in the pelvis called the greater sciatic foramen, and typically runs below the piriformis muscle. (spine-health.com)
The sciatic nerve then travels down the back of the upper thigh. (spine-health.com)
Above the back of the knee, the sciatic nerve divides into two nerves, the tibial and the common peroneal nerve, both of which serve the lower leg and foot. (spine-health.com)
Certain conditions in the lower back can irritate the sciatic nerve, causing pain to radiate along the nerve. (spine-health.com)
The dorsal and ventral roots of the sciatic nerve are responsible for symptoms along the buttocks, thigh, leg, and foot. (spine-health.com)
The sensory and motor fibers within the sciatic nerve roots are distinct and can be affected individually or together, resulting in only pain, only motor deficits, or both. (spine-health.com)
To investigate the potential role of mitochondrial DNA (mtDNA) deletions in the observed effects of EQ, we measured total mtDNA deletion burden in the distal sciatic nerve. (nature.com)

Within the layers of the retina, photons trigger a series of electrical and chemical reactions, ultimately sending electrical signals by way of the optic nerve, along with visual pathway to the occipital cortex. (medscape.com)

The skeletal muscle fiber type underwent adaptive changes due to double innervations with both fast and slow muscle nerves. (medscimonit.com)
Our results show that pressing dominant nerves alter the skeletal muscle fiber types of the peroneus longus, which lead to increased maximal contraction and relaxation time, and significantly improve the ability in resistance to fatigue in rats. (medscimonit.com)
Scholars@Duke publication: Nerve activity-dependent modulation of calcineurin signaling in adult fast and slow skeletal muscle fibers. (duke.edu)
This study tested the hypothesis that calcineurin signaling is modulated in skeletal muscle cells by fluctuations in nerve-mediated activity. (duke.edu)

Scientific tools to quantify the sizes and classification of fibers and myelination have changed very little over the past century. (mountsinai.org)

It leaves the skull through the middle compartment of the jugular foramen, where it has upper and lower ganglionic swellings, which are the sensory ganglia of the nerve. (medscape.com)

The SAE approach today corrects for size and myelination of individual nerve fibers for light and electron microscopy by compensating for the shape and dispersion angle of individual nerve fibers. (mountsinai.org)
The SAE approach was validated by light and electron microscopy against the traditional methods of determining nerve fiber size and myelination-which had resulted in significant overestimations of fiber diameters. (mountsinai.org)

The optical coherence tomography (OCT) is part of the detection and monitoring of many retinal and optic nerve diseases. (scitechnol.com)

To compare the ability of 3 instruments, the Heidelberg Retina Tomograph (HRT), the GDx Nerve Fiber Analyzer (GDx), and the Optical Coherence Tomograph (OCT), to discriminate between healthy eyes and eyes with early to moderate glaucomatous visual field loss. (glaucoma.org.il)

The aim of this study is to clarify the significance of macrophage infiltration in sural nerve (SN) in subjects with T2DM. (diabetesjournals.org)
it replaces the commonplace sural nerve biopsy check as much less intrusive [ 6 ]. (scitechnol.com)

The trochlear nerve controls the superior oblique muscle, which helps with eye movement, while the oculomotor nerve controls several eye muscles responsible for eye movement, pupil constriction, and focusing. (proprofs.com)

The effects of arsenic (7440382) on nerve conduction velocities were studied in Alaskan residents with naturally contaminated drinking water. (cdc.gov)
One or more nerve conduction velocities were abnormal in 13 subjects, but nerve velocity measurements were not related to estimated daily arsenic ingestion or arsenic concentrations in water or urine. (cdc.gov)

How do nerve fibers know where to grow and with which of the approximately hundred billion nerve cells of the brain they need to form connections? (charite.de)

examined radial, median, and ulnar nerve specimens from a CRPS-affected amputated limb and showed widespread (47-58%) selective degeneration in the larger myelinated Aα fibers (motor/proprioception) and in groups of small unmyelinated C fibers (Remak bundles), while the smaller Aδ (pain/temperature) fibers were spared. (frontiersin.org)

While the cause(s) of sciatica is mostly defined as a problem occurring at the level of the spinal nerve root, it is also possible for the dorsal or ventral roots to be affected before they merge to form the spinal nerve root. (spine-health.com)

Connections of the vagus to the glossopharyngeal and accessory nerves. (medscape.com)

The vagus nerve exits from the medulla oblongata in the groove between the olive and the inferior cerebellar peduncle. (medscape.com)

Confocal microscopy of the corneal nerve fibers]. (illumina.com)

Optic nerve MRI measurements included the length of T2 lesions, measurement of optic nerve atrophy, magnetization transfer ratio (MTR) and diffusion tensor imaging (DTI) measures. (elsevierpure.com)

Now a large and ever increasing number of genetic subtypes has been described, and major advances in molecular and cellular biology have clarified the understanding of the role of different proteins in the physiology of peripheral nerve conduction in health and in disease. (medscape.com)

Nerve pain may be incapacitating, and the intricate fibers of the nervous tissue can cause an array of symptoms, including pain, stiffness, weakness, and abnormal sensations (paresthesia). (spine-health.com)
The combination of increased pain signaling and degeneration of pain-transmitting fibers leads to a variable condition with signs and symptoms that can change over time. (medlineplus.gov)
Symptoms depend on which nerve fibers are affected. (healthline.com)

Diagram of the vagus nerve demonstrating the different branches. (medscape.com)

first, the small nerve fibers are disappearing, and those that are left are smaller in diameter than usual. (omf.ngo)

Created in the research lab of Leif Havton, MD, PhD , Professor of Neurology, and Neuroscience, at the Icahn School of Medicine at Mount Sinai, the tool-known as shape-adjusted ellipse (SAE) approach-provides an innovative way of improving the accuracy of identifying and classifying nerve fiber types needed to generate ground truth data for both light microscopy (LM) and electron microscopy (EM) studies. (mountsinai.org)

The extraocular muscles are innervated by 3 cranial nerves (CNs): oculomotor (CN III), trochlear (CN IV), and abducens nerves (CN VI). (medscape.com)

These nerve fibers, or roots, exit the spinal canal through a number of openings in the bones at each level of the lower spine called foramina. (spine-health.com)
If this tiny segment of nerve root is affected while it courses through the foramen in the lower spine, sciatica may occur. (spine-health.com)

Digital measurements of nerve fiber area and perimeter from each axon are used to determine a corrected value of fiber size based on SAE approach. (mountsinai.org)

Anatomy110

Organisms13

Diseases43

Chemicals and Drugs28

Analytical, Diagnostic and Therapeutic Techniques and Equipment36

Psychiatry and Psychology7

Phenomena and Processes22

Disciplines and Occupations3

Technology, Industry, Agriculture2

Information Science1

Health Care1

Impulses12

Neurons4

Myelin8

RNFL14

Thickness14

Glaucoma7

Epidermal Nerve Fiber Density4

Axons3

Layer7

Spinal cord10

Anatomy3

Afferent4

Neuropathy16

Cranial nerve7

Pathology1

Blood vessels2

Nervous System1

Autonomic1

Sympathetic1

Motor nerves1

Neural5

Posterior2

Originate4

Density3

Sciatic11

Signals1

Skeletal4

Quantify1

Ganglionic1

Myelination2

Optic Nerve Di1

Optical Coherence Tomograph1

Sural nerve2

Oculomotor nerve1

Conduction velocities2

Cells1

Bundles1

Dorsal1

Glossopharyngeal1

Medulla1

Corneal1

Lesions1

Physiology1

Symptoms3

Diagram1

Small nerve1

Microscopy1

Trochlear1

Spine2

Measurements1