NeprilysinNeural PathwaysPruritusNeuronsAfferent PathwaysBrainThiorphanSpinal CordRats, WistarRats, Sprague-DawleyAmyloid beta-PeptidesInsulysinEnkephalin, Leucine-2-AlanineAmyloid beta-Protein PrecursorAlzheimer DiseasePlaque, AmyloidAspartic Acid EndopeptidasesHippocampusPeptide FragmentsMice, TransgenicMetalloendopeptidasesThermolysinProtease InhibitorsAngiotensin ISubtilisinNeuronal PlasticityGlycopeptidesAngiotensinsCells, CulturedMaze LearningNerve Tissue ProteinsDisease Models, AnimalPeptidyl-Dipeptidase AMice, Inbred C57BLQuinuclidinesNitric Oxide Synthase Type IMolecular Sequence DataAmino Acid SequenceCerebral CortexAmyloidMice, KnockoutImmunohistochemistryAmyloid Precursor Protein SecretasesFuransGene Expression Regulation, EnzymologicLentivirusNeuronal Ceroid-LipofuscinosesNerve Growth FactorsHydrolysisNeurotrophin 3Cell LineNerve Growth FactorCell DeathBlotting, WesternSubstrate SpecificityNeurogliaNeuritesNeurogenesisGene Expression RegulationNerve Degeneration