Loading...
  • lesions
  • As the incidence of renal cell carcinoma (RCC) and earlier incidental detection of small kidney masses has steadily risen over the past twenty years, minimally-invasive management of these lesions has become more common. (sages.org)
  • pathology
  • Tumor pathology was as follows [HALPN (OPN)]: 80.9% (80.0%) RCC, 12.8% (8.0%) oncocytoma, and 6.4% (12.0%) angiomyolipoma. (sages.org)
  • chemotherapy
  • Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. (clinicaltrials.gov)
  • Giving more than one drug (combination chemotherapy) may kill more tumor cells. (clinicaltrials.gov)
  • Giving combination chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. (clinicaltrials.gov)
  • primary tumor
  • As PCa death is not due to the primary tumor, but rather the formation of distinct metastasis, the ability to effectively model this progression pre-clinically is of high value. (jove.com)
  • At experiment termination, several distinct endpoints can be measured, such as size and molecular characterization of the primary tumor, the presence and quantification of circulating tumor cells in the blood and bone marrow, and formation of metastasis to the lung. (jove.com)
  • Typical tumor implantation models utilize ectopic or orthotopic primary tumor implantation, but few include systemic spontaneous metastatic disease that mimics the clinical setting. (jove.com)
  • contralateral
  • However, conservative management with kidney-sparing endoscopic surgery is currently performed not only in those patients with imperative indications but also in those patients with low risk disease and normal, functioning contralateral kidneys, due to its similar oncological efficacy. (springer.com)
  • Lau WK, Blute ML, Weaver AL, Torres VE, Zincke H. Matched comparison of radical nephrectomy vs nephron-sparing surgery in patients with unilateral renal cell carcinoma and a normal contralateral kidney. (springer.com)
  • For induction of moderate injury BALB/c mice undergo unilateral clamping of the renal pedicle for 26 min and also undergo simultaneous contralateral nephrectomy. (jove.com)
  • To induce more severe AKI, BALB/c mice undergo renal pedicle clamping for 30 min followed by contralateral nephrectomy 8 days after injury. (jove.com)
  • Tumours
  • Seisen T, Colin P, Roupret M. Risk-adapted strategy for the kidney-sparing management of upper tract tumours. (springer.com)
  • metastases
  • While the 4T1 breast tumor surgery model allows for the simulation of the effects of abdominal surgical stress on tumor metastases, its applicability to other tumor types needs to be tested. (jove.com)
  • Here, a preclinical, murine pancreatic tumor model of hepatic metastases via a hemispleen injection of syngeneic murine pancreatic tumor cells is described. (jove.com)
  • Mice consistently develop metastases in the liver allowing for investigation of the metastatic process, experimental therapy testing, and tumor immunology research. (jove.com)
  • metastasis
  • Total en bloc spondylectomy (TES) is a surgery designed to achieve complete resection of a malignant spinal tumor such as spinal metastasis. (jove.com)
  • ablation
  • The procedure, called percutaneous ablation, involves the insertion of a needle through the skin into a kidney tumor, followed by the heating or freezing by the needle to destroy the tumor. (ascopost.com)
  • Percutaneous thermal ablation is an emerging treatment option for many tumors of the abdomen not amenable to conventional treatments. (jove.com)
  • During a thermal ablation procedure, a thin applicator is guided into the target tumor under imaging guidance. (jove.com)
  • Thermal tumor ablation can be performed at open surgery, laparoscopy or using a percutaneous approach. (jove.com)
  • Urology
  • The investigators, Ross J. Mason, a medical student, and Ricardo A. Rendon, MD, Associate Professor of Urology, defined a central mass as one extending into the kidney in direct contact with or invading the collecting system and/or renal sinus. (renalandurologynews.com)
  • Of note, Dr. Kenney co-authored the chapter on open kidney surgery for Campbell-Walsh Urology, the definitive and most widely read textbook in the field. (yale.edu)
  • removal
  • Hi after 3 years of planning to do pd i have just had my tube fitted and had started training on the machine when i saw the surgeon about the planned removal of one or both of my huge pkd kidneys to enable me to go on the transplant list. (kidneypatientguide.org.uk)
  • the removal of the kidney to enable a transplant has always been known so i cant understand why they gave me a false impression of the future and let me go through the op to insert the tube with all its consequential pain, discomfort, loss of work and not least cost to the nhs only for it to have to be removed again and a fistula fitted. (kidneypatientguide.org.uk)
  • surgery
  • tumors ≤ 4 cm were at least 3.8 times more likely to be treated with nephron sparing surgery. (medpagetoday.com)
  • Additionally, partial nephrectomy has a higher risk of bleeding or urine leak after surgery, which may argue against using that approach. (medpagetoday.com)
  • A prospective, randomised EORTC intergroup phase 3 study comparing the oncologic outcome of elective nephron-sparing surgery and radical nephrectomy for low-stage renal cell carcinoma. (springer.com)
  • Our purpose is to present a second-generation TES applied tumor-induced cryoimmunology and assess the immunity-enhancing effect after implementing this surgery. (jove.com)
  • mortality
  • Ischemia-reperfusion induced acute kidney injury (IR-AKI) is widely used as a model of AKI in mice, but results are often quite variable with high, often unreported mortality rates that may confound analyses. (jove.com)
  • invasive
  • In recent years there has been substantial progress in the understanding of the mechanics of tumor invasion, and direct intracerebral inoculation of tumor provides the opportunity of observing the invasive process in a physiologically appropriate environment 2 . (jove.com)