• In normal patients' colonic mucosa, phagocytic cells do not respond to the resident bacteria. (medscape.com)
  • Both neoplastic and normal mucosa were collected from each patient and subjected to histological, ultrastructural and immunohistochemical analyses. (bvsalud.org)
  • Results- Increased hypermethylation frequencies in carcinoma vs. normal colonic mucosa were detected for all the inflammatory marker genes in specimens of UC-CRC patients. (helsinki.fi)
  • Methylation of the NTSR1 in the normal colonic mucosa suggests a possible field defect in UC-CRC, and could thus be used as an early biomarker to detect increased UC-CRC risk in non-neoplastic epithelium. (helsinki.fi)
  • Colonic mucosa with gastrointestinal stromal tumor (GIST) involving the adjacent submucosa (hematoxylin and eosin [H&E] stain, medium power). (medscape.com)
  • In 22 controls, the colonic mucosa proximal or distal to surgically removed colonic adenocarcinomas was scrutinized for NDCs. (iiarjournals.org)
  • The colonic mucosa is constantly challenged by a series of carcinogenic factors able to generate mucosal foci of mutated dysplastic cells called adenomas, lesions that may eventually progress to invasive carcinoma. (iiarjournals.org)
  • Risk stratification of colon carcinogenesis through enhanced backscattering spectroscopy analysis of the uninvolved colonic mucosa. (nih.gov)
  • We show, for the first time, that enhanced backscattering analysis of an aliquot of uninvolved mucosa has the potential for predicting neoplastic risk throughout the colon in both experimental colorectal cancer models and humans. (nih.gov)
  • Influence of the application of enemas with oily extract of curcumin ( Curcuma longa ) on the tissue content of neutral and acidic mucins in the colonic mucosa without fecal stream ☆ ☆ Study conducted at Universidade São Francisco (USF), Programa de Pós-Graduação em Ciências da Saúde, Laboratório de Investigação Médica (LIM), Bragança Paulista, SP, Brazil. (scielo.br)
  • To verify if the application of enemas containing oily extracts of curcumin preserves the tissue content of mucins in the glands of the colonic mucosa without fecal stream. (scielo.br)
  • Ulcerative Colitis Ulcerative colitis is a chronic inflammatory and ulcerative disease arising in the colonic mucosa, characterized most often by bloody diarrhea. (msdmanuals.com)
  • Colonic polyps are subdivided into two major groups: non-neoplastic and neoplastic . (webpathology.com)
  • Non-neoplastic group includes hyperplastic polyps, hamartomatous polyps (juvenile polyps, Peutz-Jeghers polyps), inflammatory polyps and mucosal polyps . (webpathology.com)
  • Neoplastic polyps show epithelial dysplasia by definition and include adenomas and carcinomas . (webpathology.com)
  • Serrated adenomas , which are related to hyperplastic polyps, have malignant potential and are now considered neoplastic. (webpathology.com)
  • We found a lot of parasitic infections, but we never found colonic polyps or colon cancer, or extremely rarely. (voanews.com)
  • Current classification systems based on narrow band imaging (NBI), however, do not include neoplastic sessile serrated adenomas/polyps (SSA/Ps). (bmj.com)
  • The cases included 5 gastrointestinal tumors all presenting as colonic pedunculated polyps, 2 presenting as mesocolon mass, and 2 involving the palatine or nasopharyngeal tonsils. (lww.com)
  • The aim of this study is to find out the early changes and high risk factors related to carcinogenesis in colonic polyps. (uwi.edu)
  • METHODS: This is a cross-sectional study including asymptomatic patients who underwent a screening colonoscopy (patients with a positive fecal occult blood test under the regional program of colorectal cancer (CRC) screening), surveillance after polypectomy resection, or familiarity (first-degree relatives) between 2020 and 2021 to evaluate the association between diverticula and colonic polyps. (bvsalud.org)
  • Familial Adenomatous Polyposis Familial adenomatous polyposis is a hereditary disorder causing numerous colonic polyps and frequently results in colon carcinoma, often by age 40. (msdmanuals.com)
  • Adenomatous (neoplastic) polyps are of greatest concern. (msdmanuals.com)
  • The combined negative predictive value with high confidence of diminutive neoplastic lesions (adenomas and SSA/Ps together) was 0.91 (95% CI 0.83 to 0.96). (bmj.com)
  • Adenomas are benign neoplastic lesions which can be transformed into carcinomas, but this is usually not the case. (uwi.edu)
  • Background: Colonic crypts with normal epithelial lining displaying corrupted shapes (called non-dysplastic crypts with corrupted shapes, NDCs) were earlier recorded underneath the adenomatous glands of conventional colon adenomas in rats. (iiarjournals.org)
  • Considering that human colonic crypts typically divide at most once or twice during a lifetime, with an average crypt cycle length of 36 years, the accumulation of NDCs underneath sporadic conventional adenomas is remarkable. (iiarjournals.org)
  • Group I: Fission distortions exhibited by nondysplastic corrupted colonic crypts (NDCs) underneath conventional (tubular/villous) colonic adenomas. (iiarjournals.org)
  • In vivo, NTSR1 mRNA expression was undetectable in superficial differentiated epithelial cells in histological specimens of normal human colonic epithelium, but there was moderate and strong expression in adenomas and adenocarcinomas respectively. (springer.com)
  • A statistically significant association between adenomas or CRC alone and colonic diverticula was found (p = 0.045). (bvsalud.org)
  • CONCLUSIONS: This study showed a statistically significant association between diverticula and colonic adenomas. (bvsalud.org)
  • The colonic carcinoma, the adenomas and the normal tissue showed strong nuclear reactivity to hMSH2 and hMSH6 in 96.9% of the cases. (who.int)
  • Objective Accurate endoscopic differentiation would enable to resect and discard small and diminutive colonic lesions, thereby increasing cost-efficiency. (bmj.com)
  • Further metabolism by colonic bacteria that produce β-glucuronidase generates methyldiazonium, which can initiate cancer by inducing mutagenic lesions in target cells by the alkylation of DNA at the O6 position of guanine 17 . (scialert.net)
  • We prospectively identified 30 patients who tested positive with a commercially available sDNA followed by colonoscopy without neoplastic lesions. (nih.gov)
  • We determined the presence of neoplastic lesions on repeat evaluation stratified by results of repeat sDNA. (nih.gov)
  • PURPOSE: If could be a potential pathophysiological connection between colonic diverticula and colonic superficial neoplastic lesions, beyond the shared risk factors, has been a subject of debate in the last years. (bvsalud.org)
  • This study tries to evaluate the association between diverticulosis and colonic neoplastic lesions. (bvsalud.org)
  • A Microbiomic Analysis in African Americans with Colonic Lesions Reveals Streptococcus sp.VT162 as a Marker of Neoplastic Transformation. (cdc.gov)
  • Accordingly, immunohistochemistry with specific antibodies shows that HMGCS2 is expressed mainly in differentiated cells of human colonic epithelium. (aacrjournals.org)
  • Histologically, the mass comprises a core of connective tissue covered with hyperplastic glandular epithelium of colonic type, with focal nuclear atypia. (anatomywarehouse.com)
  • The stalk is usually non-neoplastic epithelium. (anatomywarehouse.com)
  • Enemas with curcumin preserve the content of neutral and acidic mucins in the colonic epithelium without fecal stream. (scielo.br)
  • 25 consecutive colon samples were collected from patients undergoing colonic resection. (bvsalud.org)
  • The patient was managed with colonic resection and made an uneventful recovery. (scielo.org.za)
  • This case suggests that other than surgical resection of the neoplasm, CAM and PSL treatment for RS3PE associated with neoplastic disease may be effective. (sch.ac.kr)
  • Predictive factors for successful colonic stenting in acute large-bowel obstruction: a 15-year cohort analysis. (thieme-connect.com)
  • Comparison of long-term outcomes of colonic stent as "bridge to surgery" and emergency surgery for malignant large-bowel obstruction: a meta-analysis. (thieme-connect.com)
  • If the role of human papillomavirus is elucidated in colonic carcinogenesis, vaccination might prevent carcinogenesis from the virus. (uwi.edu)
  • To determine the prevalence of missed colonic or occult upper gastrointestinal neoplasia in patients with an apparent false positive sDNA. (nih.gov)
  • Self-expandable metal stents for obstructing colonic and extracolonic cancer: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline. (thieme-connect.com)
  • In CaCo-2 colonic epithelial cells, the expression of this gene increases with cell differentiation. (aacrjournals.org)
  • One patient with a colonic tumor was complicated by paraneoplastic pemphigus. (lww.com)
  • Defects in the formation of a colonic mucous lining impermeable to bacterial penetration have been associated with inflammatory bowel diseases. (edu.au)
  • Because water is normally absorbed from the colonic content, principally in the ascending, or right, colon, diarrhea can be caused by any inflammatory, neoplastic, or vascular disturbance of that part of the colon. (britannica.com)
  • NTSR1 gene showed significantly increased methylation of normal colonic mucosae from UC-CRC vs. LS patients (p value=0.01). (helsinki.fi)
  • A study with a prospective design including both patients with diverticulosis and without colonic diverticula aimed at establishing the incidence of adenoma and CRC could help to answer this relevant clinical question, since a potential association could indicate the need for closer endoscopic surveillance. (bvsalud.org)
  • The main risks for the growth of a sporadic conventional adenoma include family history, advanced age, male sex, lifestyle, natural exposure to dietary/environmental carcinogens, genetic differences, obesity, type 2 diabetes, the colonic microbiome ( 6 ) and the disintegration of the subepithelial macrophage barrier against the gut microbiota ( 7 ). (iiarjournals.org)
  • Is stenting as "a bridge to surgery" an oncologically safe strategy for the management of acute, left-sided, malignant, colonic obstruction? (thieme-connect.com)
  • Stent as bridge to surgery for left-sided malignant colonic obstruction reduces adverse events and stoma rate compared with emergency surgery: results of a systematic review and meta-analysis of randomized controlled trials. (thieme-connect.com)
  • 15 Sagar J. Colorectal stents for the management of malignant colonic obstructions. (thieme-connect.com)
  • Oncologic outcomes of self-expandable metallic stent as a bridge to surgery and safety and feasibility of minimally invasive surgery for acute malignant colonic obstruction. (thieme-connect.com)
  • Spindled to oval neoplastic cells with ill-defined cell borders were dispersed or formed loose whorled fascicles in a dense lymphoplasmacytic background. (lww.com)
  • The neoplastic cells showed variable expression of FDC markers and were labeled for Epstein-Barr virus-encoded RNA on in situ hybridization. (lww.com)
  • Solitary extramedullary plasmacytoma (SEP) is a neoplastic proliferation of a single clone of plasma cells that occur outside of the bone and bone marrow. (scielo.org.za)
  • Our research focuses on developmental pathways that regulate hematopoietic cell growth and differentiation and are disrupted in the course of neoplastic transformation, particularly in leukemias and lymphomas. (stanford.edu)
  • The present study therefore aimed to investigate the utility of using the Winnie mouse to model the progression of chronic colitis to colonic cancer. (edu.au)
  • This shows that you can change your environment very acutely with a dietary change,' O'Keefe said, 'and it has dramatic effects on the interior milieu of the colon, namely the microbiota, and the way that it metabolizes in the digestive system to produce things that either preserve colonic health or actually produce inflammation and increase risk of neoplastic change. (voanews.com)
  • 1980. Inhibition by bran of the colonic cocarcinogenicity of bile salts in rats given dimethylhydrazine. (cdc.gov)
  • Most epidemiological and experimental studies conducted to determine the effects of milk and dairy product consumption on neoplastic development have focused on bovine milk 5 - 8 , whereas information on camel milk and other types of milk are scarce. (scialert.net)
  • [ 3 ] Mutations in the c-kit receptor are linked to the neoplastic development. (medscape.com)
  • New procedure for the treatment of colorectal neoplastic obstructions. (thieme-connect.com)
  • Glucocorticoid (GC) remains the mainstay of treatment for RS3PE not associated with neoplastic disease. (sch.ac.kr)
  • GC therapy usually dramatically improves the clinical picture, but is known to be of limited use for RS3PE associated with neoplastic disease. (sch.ac.kr)
  • 2 2 Gaudier E, Hoebler C. Physiological role of mucins in the colonic barrier integrity. (scielo.br)