• OBJECTIVE: To identify CT features and establish a diagnostic model for distinguishing non-ampullary duodenal neuroendocrine neoplasms (dNENs) from non-ampullary duodenal gastrointestinal stromal tumors (dGISTs) and to analyze overall survival outcomes of all dNENs patients. (bvsalud.org)
  • Neuroendocrine tumors (NETs) of duodenal origin are an unusual subset among all NETs, comprising only about 3% of this neoplasm class. (bvsalud.org)
  • All 3 lesions contained myelolipomatous foci throughout the neoplasm, and 2 of the tumors contained several pure lipomatous foci. (medscape.com)
  • Lipoma is a benign mesenchymal neoplasm of soft tissue composed of mature adipocyte cells, being among the most common benign tumors. (bvsalud.org)
  • Though not commonly seen in the oral cavity, lipoma is a benign tumor of the soft tissue composed of mature adipose cells without cellular atypia, equating to between 15% and 20% of cases involving the head and neck region and between 1% and 5% of all benign tumors of the oral cavity 1-4 . (bvsalud.org)
  • Some lesions of the oral cavity may not be genuine benign tumors, being herniations of the adipose cushion of the cheek mucosa 4 , a fact which alerts the professional responsible for the diagnosis to an understanding of the main clinical characteristics of this benign neoplasm. (bvsalud.org)
  • It is more probable that lipomas are at the benign end of the spectrum of tumors, which, at the malignant end, include liposarcomas (see Pathophysiology ). (medscape.com)
  • HSPA5, highly expressed in the malignant tumors, likely plays a critical role in SARS-CoV-2 invasion/attack in cancer patients via tumor tissues. (bvsalud.org)
  • Adrenal myelolipoma is a rare benign neoplasm composed of mature adipose tissue and a variable amount of hematopoietic elements. (medscape.com)
  • Background: Perivascular epithelioid cell tumours (PEComas) are mesenchymal neoplasms with variable biological behaviour, ranging from benign to extremely aggressive diseases able to metastasize. (fortuneonline.org)
  • UCP1 is highly expressed in brown adipose tissue (BAT), including hibernomas, but its expression in other adipose tumours is uncertain. (biomedcentral.com)
  • UCP1 has also been found in other tissues (e.g. smooth muscle) but whether it is expressed in non-adipose benign and malignant soft tissue tumours is unknown. (biomedcentral.com)
  • Immunohistochemical staining of normal (axillary) BAT and subcutaneous/abdominal white adipose tissue (WAT) as well as a wide range of benign and malignant primary soft tissue tumours (n = 171) was performed using a rabbit polyclonal antibody to UCP1. (biomedcentral.com)
  • UCP1 was not expressed in WAT or other adipose tumours with the exception a few tumour cells in pleomorphic liposarcoma. (biomedcentral.com)
  • UCP1 is strongly expressed in BAT but not WAT and is found in all hibernomas and a few pleomorphic liposarcomas but not in other adipose tumours. (biomedcentral.com)
  • Benign and malignant tumours of adipose differentiation represent a large category of soft tissue tumours, many of which are frequently encountered in diagnostic pathology [ 1 ]. (biomedcentral.com)
  • In specific subtypes of benign and malignant adipose tumours there may be lipoblasts and/or atypical adipose cells with large or small, single or multiple, fat vacuoles as well as cells with pleomorphic or spindle-shaped nuclei [ 1 ]. (biomedcentral.com)
  • In addition, as UCP1 has been reported in other cell types, we have examined whether UCP1 is expressed in a wide range of non-adipose benign and malignant soft tissue tumours. (biomedcentral.com)
  • We have also determined whether tumour markers other than UCP1 can be used to distinguish hibernoma from other adipose/non-adipose soft tissue tumours. (biomedcentral.com)
  • UCP1 expression in a few non-adipose soft tissue sarcomas may possibly reflect origin of tumour cells from a common mesenchymal stem cell precursor and/or developmental pathway. (biomedcentral.com)
  • Montone et al presented pathologic and radiographic features of 3 patients with adrenocortical neoplasms. (medscape.com)
  • Pathologically, 2 of the lesions were classified as adrenocortical neoplasms of uncertain malignant potential, and 1 lesion was classified as an adrenocortical adenoma. (medscape.com)
  • The presence of mature adipose tissue intermixed with hematopoietic elements, including megakaryocytes on cytology or histology, is diagnostic of myelolipoma. (medscape.com)
  • Low-power view of hematoxylin-eosin-stained bone marrow showing hypocellularity, with increased adipose tissue and decreased hematopoietic cells in the marrow space. (medscape.com)
  • Distemper virus invades the upper respiratory mucosa, proliferates in lymphoid tissues, and becomes viremic. (vin.com)
  • Lipomas have an etiology and pathogenesis that are still uncertain 3,6 , although there are a number of reports that they may be related to the inflammatory, endocrine and mechanical processes5. (bvsalud.org)
  • The pathogenesis of leiomyoma is characterized by benign smooth muscle neoplasm . (wikidoc.org)
  • Lipomas are the most common soft-tissue tumor. (medscape.com)
  • Colonic lipomas are uncommon nonepithelial neoplasms that are typically sessile, asymptomatic and incidentally found during endoscopy, surgery, or autopsy. (biomedcentral.com)
  • Myelolipomas may be discovered incidentally on ultrasonography (US), which otherwise is not used routinely to characterize adrenal neoplasms. (medscape.com)
  • In these patients, the multiplanar capability of MRI can help to define the tissue planes and confirm that the mass is adrenal in origin. (medscape.com)
  • Malignant neoplasm of the Adrenal gland is rare and carries a poor prognosis. (endocrine-abstracts.org)
  • However, there is no consistent evidence of glucocorticoid excess in simple obesity, suggesting that its role in the regulation of adipose tissue mass results from a more complex mechanism than adrenal hypersecretion of glucocorticoid. (endocrine-abstracts.org)
  • Symptoms may include nonspecific abdominal pain, constipation, vomiting, hematuria, or renovascular hypertension because of intratumoral hemorrhage or compression of peritumoral tissue. (medscape.com)
  • The histological examination revealed mature fat cells, connective tissue, and scattered blood vessels within the removed submucosal mass (Figure 4 ). (biomedcentral.com)
  • Angiosarcomas are composed of a malignant population of endothelial-type cells forming complex anastomosing channels. (basicmedicalkey.com)
  • The fusion of insulin-stimulated GLUT4-containing vesicles (GSV) with the plasma membrane (PM) of adipose or skeletal muscle cells is governed by regulated exocytosis. (endocrine-abstracts.org)
  • BAT and hibernomas were also stained by immunohistochemistry with monoclonal and polyclonal antibodies to adipose/non-adipose tumour markers in order to characterise the immunophenotype of BAT cells. (biomedcentral.com)
  • UCP1 was variably expressed by tumour cells in a few non-adipose sarcomas including leiomyosarcoma, rhabdomyosarcoma, alveolar soft part sarcoma, synovial sarcoma and clear cell sarcoma. (biomedcentral.com)
  • However, it is still uncertain about the interplay of autophagy and swine acute diarrhea syndrome coronavirus (SADS-CoV) in cells. (bvsalud.org)
  • Therefore, we propose that damage to and subsequent release of mtDNA elicits a protective signalling response that enhances nDNA repair in cells and tissues, suggesting that mtDNA is a genotoxic stress sentinel. (regenerativemedicine.net)
  • However, it is uncertain how this score is related to other biological effects such as vascular risk.Methods: Sixteen hypopituitary patients were recr. (endocrine-abstracts.org)
  • In pelvis were observed several expansive lesions, the greater ones of about 4 cm, that was extended to the aortic carrefour, the right common and external iliac regions, and to presacral adipose tissue, close to the periosteum. (fortuneonline.org)
  • Gynecomastia (also spelled gynaecomastia) is the abnormal non-cancerous enlargement of one or both breasts in males due to the growth of breast tissue as a result of a hormone imbalance between estrogens and androgens. (wikipedia.org)
  • Gynecomastia is the most common benign disorder of the male breast tissue and affects 35% of men, being most prevalent between the ages of 50 and 69. (wikipedia.org)
  • A soft, compressible, and mobile mass of breast tissue is felt under the nipple and its surrounding skin in contrast to softer fatty tissue which is not associated with a mass. (wikipedia.org)
  • Estrogen and androgens have opposing actions on breast tissue: estrogens stimulate proliferation while androgens inhibit proliferation. (wikipedia.org)
  • [ 9 ] One theory suggests that trauma-related fat herniation through tissue planes creates so-called pseudolipomas. (medscape.com)
  • The only prospective study published is the phase 2 AMPECT trial, that evaluated the efficacy and safety of nab-sirolimus in 34 advanced malignant PEComas. (fortuneonline.org)
  • In this study, we have sought to determine whether UCP1 is expressed in specific benign and malignant adipose tumour subtypes. (biomedcentral.com)
  • Medications such as aromatase inhibitors have been found to be effective and even in rare cases of gynecomastia from disorders such as aromatase excess syndrome or Peutz-Jeghers syndrome, but surgical removal of the excess tissue can be needed to correct the condition. (wikipedia.org)
  • Chordoma is a rare, slow growing and locally aggressive mesenchymal neoplasm with uncommon distant metastases. (biomedcentral.com)
  • Solitary fibrous tumor is an unusual fibroblastic mesenchymal neoplasm typically described in the pleura. (biomedcentral.com)
  • Pathologically, 2 of the lesions were classified as adrenocortical neoplasms of uncertain malignant potential, and 1 lesion was classified as an adrenocortical adenoma. (medscape.com)
  • Histologically, the resected polyp was a lipomatous lesion in the submucosal layer, composed of mature adipose tissues. (bvsalud.org)
  • If the diagnosis of a lesion is uncertain or if a lesion has exhibited unexpected or rapid changes in appearance or symptoms, a diagnostic procedure (eg, biopsy, excision) is indicated for a precise diagnosis. (medilib.ir)
  • This variant has been reported in the literature as a somatic event (present in tissue from a lesion but not in non-lesional tissue or peripheral blood) in individuals with nevus sebaceous syndrome (PMID: 23255105, 22683711, 23096712, 26521233). (varsome.com)
  • 1. Metastatic nonhematopoietic neoplasms to the breast: a study of 238 cases. (nih.gov)
  • From the abstract: ' Mammography images contain a lot of information about not only the mammary glands but also the skin, adipose tissue, and stroma, which may reflect the risk of developing breast cancer. (cdc.gov)
  • 2. Angiofibroma of soft tissue: Current status of pathology and genetics. (nih.gov)
  • Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft tissue tumor that typically affects the lower limbs of men between the ages of 50 and 60. (biomedcentral.com)
  • We recently reported outcomes from a Scandinavian Sarcoma Group adjuvant study (SSG XX group A) conducted on localized and operable high risk soft tissue sarcoma (STS) of the extremities and trunk wall. (biomedcentral.com)
  • Dermatofibroma - Dermatofibroma, also called benign fibrous histiocytoma, is one of the most common cutaneous soft-tissue lesions. (medilib.ir)
  • This tumor may be classified as a "neoplasm with uncertain malignant potential" in a lipoma, an intermediate category between adenoma and invasive adenocarcinoma. (bvsalud.org)
  • This is the first report of a duodenal gastric-type neoplasm with uncertain malignant potential in a lipoma. (bvsalud.org)
  • Colonic lipomas are uncommon nonepithelial neoplasms that are typically sessile, asymptomatic and incidentally found during endoscopy, surgery, or autopsy. (biomedcentral.com)
  • However, it has been reported that they are uncommon in the oral cavity, representing between 15% and 20% of cases involving the head and neck, and between 1% and 5% of all benign neoplasms of the oral cavity. (bvsalud.org)
  • Since myelolipomas contain different proportions of fat and myeloid tissue, a definitive diagnosis using computed tomography (CT) scanning or magnetic resonance imaging (MRI) may be difficult, although rarely so, if only a small amount of fat is present. (medscape.com)
  • The histological examination revealed mature fat cells, connective tissue, and scattered blood vessels within the removed submucosal mass (Figure 4 ). (biomedcentral.com)
  • Estrogen and androgens have opposing actions on breast tissue: estrogens stimulate proliferation while androgens inhibit proliferation. (wikipedia.org)
  • After menopause, adipose tissue is the major source of estrogen, and obese postmenopausal women have both higher levels of endogenous estrogen and a higher risk of breast cancer. (health.am)
  • The term cellulitis commonly is used to indicate a nonnecrotizing inflammation of the skin and subcutaneous tissues, usually from acute infection. (medscape.com)
  • Gynecomastia is the most common benign disorder of the male breast tissue and affects 35% of men, being most prevalent between the ages of 50 and 69. (wikipedia.org)
  • A soft, compressible, and mobile mass of breast tissue is felt under the nipple and its surrounding skin in contrast to softer fatty tissue which is not associated with a mass. (wikipedia.org)
  • the variant was not detected in blood or unaffected skin tissue of these individuals (Groesser et al. (varsome.com)
  • Skin cancer can spread to and damage nearby tissue and spread to other parts of the body. (healthjade.net)
  • Adrenal myelolipoma is a rare benign neoplasm composed of mature adipose tissue and a variable amount of hematopoietic elements. (medscape.com)
  • Gynecomastia (also spelled gynaecomastia) is the abnormal non-cancerous enlargement of one or both breasts in males due to the growth of breast tissue as a result of a hormone imbalance between estrogens and androgens. (wikipedia.org)
  • The presence of mature adipose tissue intermixed with hematopoietic elements, including megakaryocytes on cytology or histology, is diagnostic of myelolipoma. (medscape.com)
  • Montone et al presented pathologic and radiographic features of 3 patients with adrenocortical neoplasms. (medscape.com)
  • Pathognomonic features of carcinoma include circumferential perineural invasion, glomerulations, mucinous fibroplasia, and glands infiltrating adipose tissue. (cap.org)
  • Depletion of norepinephrine from tissue receptor sites is thought to be responsible for the decrease in peripheral vascular resistance and subsequent fall in blood pressure. (nih.gov)
  • We describe a rare case of a duodenal gastric-type neoplasm in a 50-year-old woman. (bvsalud.org)
  • Medications such as aromatase inhibitors have been found to be effective and even in rare cases of gynecomastia from disorders such as aromatase excess syndrome or Peutz-Jeghers syndrome, but surgical removal of the excess tissue can be needed to correct the condition. (wikipedia.org)
  • This system will improve upon uncertain JavaScript of infrequent Device and 31-MAR-2006 review after method change in the ascites antagonist diltiazem. (xtenddigital.com)