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  • lesions
  • The HAMN was proposed to include the lesions that have high-grade atypia and thus cannot be grouped as an LAMN, but also do not have the infiltrative invasion to be characterised as an appendiceal mucinous adenocarcinoma 1-2 . (radiopaedia.org)
  • neuroendocrine neoplasms
  • The aim of this thesis was to investigate biological and clinical aspects of G3 gastroenteropancreatic neuroendocrine neoplasms (G3 GEP-NENs). (diva-portal.org)
  • ANAHEIM, CA - Peptide receptor radionuclide therapy (PRRT) has been shown to be safe and effective for patients with grade 3 (G3) neuroendocrine neoplasms (NENs), according to research presented at the Society of Nuclear Medicine and Molecular Imaging's (SNMMI) 66th Annual Meeting. (snmmi.org)
  • While numerous studies have demonstrated the effectiveness of PRRT in well-differentiated grade 1 and 2 neuroendocrine neoplasms, limited data has been reported on PRRT in G3 NENs," noted Richard P. Baum, MD, PhD, chairman and clinical director at THERANOSTICS Center for Molecular Radiotherapy and Precision Oncology in Bad Berka, Germany. (snmmi.org)
  • BCL2
  • Design and Methods We performed a detailed immunohistochemical (CD10, IRF4/MUM1, BCL2, Ig light chains) and genetic (translocations of BCL2 , BCL6 , MYC , IRF4 ) characterization of the largest series of purely follicular cases of grade 3B follicular lymphoma available to date, comprising 23 tumor samples. (haematologica.org)
  • Both follicular lymphoma grade 3B and diffuse large B-cell lymphoma/follicular lymphoma grade 3B were enriched in samples with a CD10 − IRF4/MUM1 + immunophenotype (8/19, 42% and 7/16, 44%), with the vast majority of them lacking BCL2 translocations. (haematologica.org)
  • Conclusions Our results show that grade 3B follicular lymphomas form a distinct category of follicular lymphomas with infrequent BCL2 and BCL6 translocations, while grades 1, 2 and 3A follicular lymphomas and FL/LCC display homogeneous features with frequent BCL2 translocations and a CD10 + IRF4/MUM1 − immunophenotype. (haematologica.org)
  • data
  • Follicular lymphoma grade 3 can be further divided into types A and B. Almost all available genetic data on grade 3B follicular lymphomas have been generated from tumors with an additional diffuse large B-cell lymphoma component. (haematologica.org)
  • predict
  • Conclusion: A panel of methylated gene markers quantified by dd-QMSP can be used to predict the grade of dysplasia of pancreatic cysts. (aacrjournals.org)
  • SHOX2 is a Potent Independent Biomarker to Predict Survival of WHO Grade II-III Diffuse Gliomas. (cancerindex.org)
  • cases
  • Most cases of FL are composed mainly of centrocytes, with a few interspersed centroblasts [FL grades 1 and 2 according to the World Health Organization (WHO) classification]. (haematologica.org)