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  • rodent neocortex
  • Are the cell cycle durations that have been measured in the small, rapidly developing rodent neocortex conserved in a primate with a 100-fold larger neocortex ( 16 ) and 10-fold longer neurogenetic period ( 8 )? (pnas.org)
  • Here, we describe a new, highly selective approach for labeling astrocytes in intact rodent neocortex that allows in vivo imaging using two-photon microscopy. (nih.gov)
  • hippocampus
  • 30-40 g) and four male Sprague-Dawley rats (300-400 g) were implanted with a microdrive that allowed the positioning of recording electrodes in the somatosensory neocortex and/or the dorsal hippocampus. (pnas.org)
  • glia
  • We describe automated technologies to probe the structure of neural tissue at nanometer resolution and use them to generate a saturated reconstruction of a sub-volume of mouse neocortex in which all cellular objects (axons, dendrites, and glia) and many sub-cellular components (synapses, synaptic vesicles, spines, spine apparati, postsynaptic densities, and mitochondria) are rendered and itemized in a database. (nih.gov)
  • brain
  • The neocortex plays a key role in higher-order brain functions, such as perception, language and decision-making. (biologists.org)
  • Here we describe a procedure for tissue clearing, fluorescent labeling, and large-scale imaging of mouse brain tissue which, thereby, enables visualization of the three-dimensional organization of cell types in the neocortex. (jove.com)
  • primate
  • These findings suggest that evolutionary modification of the duration and number of progenitor cell divisions contributed to both the expansion and laminar elaboration of the primate neocortex. (pnas.org)
  • The increased number of cells in the enlarged primate neocortex presumably reflects evolutionary modifications in the neurogenetic program, resulting in greater cell production. (pnas.org)
  • Presentation] The function and the regulation of the genes selectively expressed in the primate neocortex. (nii.ac.jp)
  • rhythms
  • We introduce synaptic scaling to a biologically-realistic spiking model of neocortex which can learn changes in oscillatory rhythms using STDP, and show that scaling is necessary to balance both positive and negative changes in input from potentiation and atrophy. (springer.com)
  • Structural
  • It is generally accepted that two defining structural and functional features of the neocortex are lamination and radial columns ( Douglas and Martin, 2004 ). (biologists.org)
  • formation
  • It is thought that understanding the formation of the layers and areas can contribute to understanding the basic principle underlying the function of the neocortex. (nii.ac.jp)
  • reveal
  • These data reveal a cell-autonomous role of Dab1 in dendritogenesis in the neocortex and suggest that remodeling of the leading process of a migrating neuron into a nascent dendrite by Reelin/Dab1 signaling plays an important role in cell positioning. (jneurosci.org)
  • findings
  • These findings suggest that the rat VM l conveys and encodes cutaneous nociceptive inputs from any part of the body surface to layer I of the dorsolateral neocortex. (jneurosci.org)
  • include
  • Sleep patterns of the neocortex include thalamocortical sleep spindles (12-18 Hz) and delta waves (1-4 Hz) ( 13 , 22 ). (pnas.org)
  • further
  • This online minable database provides general access to the intrinsic complexity of the neocortex and enables further data-driven inquiries. (nih.gov)