Loading...
  • Efficacy
  • The development of new cytotoxic and targeted therapies, in particular immune checkpoint inhibitors, warrants well-designed prospective studies to test their efficacy alone or in combination in the neoadjuvant setting. (ovid.com)
  • The Pharmacology & Experimental Therapeutics Committee has increasingly focused on pharmacogenetics, the study of how genetic variation may impact on the toxicity or efficacy of drug therapy. (wikipedia.org)
  • tumor
  • After Herceptin and Taxol therapy, tumor assessment will be performed along with an echocardiogram and mammogram. (clinicaltrials.gov)
  • For the current study we tested whether applying this threshold of 60% reduction in tumor FDG SUVmax after completion of therapy in a prospectively enrolled study group yielded reliable histopathologic response predictions in patients with bone sarcomas. (hindawi.com)
  • Cancer cell heterogeneity can cause disease progression when molecularly targeted therapy, fails to kill those tumor cells which do not express the marker, then divide and mutate further, creating a new heterogeneous tumour. (wikipedia.org)
  • underwent
  • Postoperatively, the patient underwent radiotherapy for residual tracheal lesion, followed by RAI therapy for avid cervical and pulmonary disease. (scielo.br)
  • Participants underwent a pretreatment (baseline) PET/CT scan and a followup scan after the completion of neoadjuvant therapy. (hindawi.com)
  • breast
  • Using targeted therapy to block activation of those pathways further enhances the chemosensitivity of HER2-positive breast cancer, increasing the pCR rate. (uptodate.com)
  • See 'General principles of neoadjuvant therapy for breast cancer' . (uptodate.com)
  • Risk factors for developing breast cancer include being female, obesity, lack of physical exercise, drinking alcohol, hormone replacement therapy during menopause, ionizing radiation, early age at first menstruation, having children late or not at all, older age, and family history. (wikipedia.org)
  • patient
  • In some cases, trials have become an ongoing process that regularly adds and drops therapies and patient groups as more information is gained. (wikipedia.org)
  • cancer
  • There are two general causes of antineoplastic therapy failure: Inherent genetic characteristics, giving cancer cells their resistance, which is rooted in the concept of cancer cell heterogeneity and acquired resistance after drug exposure. (wikipedia.org)
  • either M0 or M1) If the stage is based on removal of the cancer with surgery and review by the pathologist, the letter p (for pathologic) or yp (pathologic after neoadjuvant therapy) may appear before the T and N letters. (wikipedia.org)
  • disease
  • Another related concept is that neoadjuvant therapy acts on micrometastatic disease. (wikipedia.org)
  • Unresectable locoregional disease remains a challenge, as standard therapy with RAI becomes unfeasible. (scielo.br)
  • Accordingly, they can be used in both noncount and count senses (for example, therapy for chronic kidney disease can involve several dialysis treatments per week). (wikipedia.org)