Negatively regulates the kinase. Medical search. Frequent questions

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Anatomy12

Cell Line Cell Line, Tumor Tumor Cells, Cultured Cells, Cultured 3T3 Cells HeLa Cells Cell Nucleus Cell Membrane Fibroblasts Cytosol PC12 Cells Cytoplasm

Organisms8

Rats, Sprague-Dawley Mice, Knockout Cattle Mice, Inbred C57BL Saccharomyces cerevisiae Rabbits Cricetinae Cercopithecus aethiops

Chemicals and Drugs179

Phosphatidylinositol 3-Kinases Protein Kinases Protein-Serine-Threonine Kinases Protein Kinase Inhibitors Calcium-Calmodulin-Dependent Protein Kinases src-Family Kinases Protein Kinase C p38 Mitogen-Activated Protein Kinases Cyclic AMP-Dependent Protein Kinases Mitogen-Activated Protein Kinase 1 p21-Activated Kinases Mitogen-Activated Protein Kinase Kinases JNK Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinase 3 Protein-Tyrosine Kinases Creatine Kinase CDC2 Protein Kinase Cyclin-Dependent Kinases MAP Kinase Kinase Kinases eIF-2 Kinase Casein Kinase II Casein Kinases Pyruvate Kinase Ribosomal Protein S6 Kinases MAP Kinase Kinase 1 Receptor Protein-Tyrosine Kinases Thymidine Kinase Extracellular Signal-Regulated MAP Kinases MAP Kinase Kinase 4 1-Phosphatidylinositol 4-Kinase Phosphotransferases (Alcohol Group Acceptor)Mitogen-Activated Protein Kinases CDC2-CDC28 Kinases I-kappa B Kinase Glycogen Synthase Kinase 3 Aurora Kinases rho-Associated Kinases Isoenzymes Protein Kinase C-delta Protein Kinase C-alpha Proto-Oncogene Proteins Diacylglycerol Kinase AMP-Activated Protein Kinases Proto-Oncogene Proteins c-akt Focal Adhesion Kinase 1 Myosin-Light-Chain Kinase Janus Kinase 2 Focal Adhesion Protein-Tyrosine Kinases Ribosomal Protein S6 Kinases, 90-kDa Tyrosine Intracellular Signaling Peptides and Proteins Phosphoproteins Protein Kinase C-epsilon MAP Kinase Kinase Kinase 1 Calcium-Calmodulin-Dependent Protein Kinase Type 2 Protein Kinase C beta Tetradecanoylphorbol Acetate MAP Kinase Kinase 2 Cyclin-Dependent Kinase 2 Serine Cyclic GMP-Dependent Protein Kinases Androstadienes TOR Serine-Threonine Kinases Cyclin-Dependent Kinase 5 Recombinant Proteins Phosphoglycerate Kinase Chromones Phosphorylase Kinase Arginine Kinase Recombinant Fusion Proteins Cell Cycle Proteins Nucleoside-Phosphate Kinase MAP Kinase Kinase 6 Morpholines Casein Kinase I MAP Kinase Kinase 3 Mitogen-Activated Protein Kinase 8 Aurora Kinase A 3-Phosphoinositide-Dependent Protein Kinases Focal Adhesion Kinase 2 Cyclic AMP RNA, Messenger Flavonoids Phosphatidylinositol 3-Kinase Calcium Adenosine Kinase Lim Kinases Enzyme Inhibitors Nucleoside-Diphosphate Kinase Choline Kinase Ribosomal Protein S6 Kinases, 70-kDa Elongation Factor 2 Kinase Threonine Pyridines raf Kinases MAP Kinase Kinase 7 Indoles Phosphotyrosine Phosphoprotein Phosphatases DNA-Binding Proteins Adaptor Proteins, Signal Transducing Aurora Kinase B Cyclin-Dependent Kinase 4 Janus Kinase 1 Adenosine Triphosphate Cyclin-Dependent Kinase Inhibitor p27 Staurosporine Phosphoserine Pyrimidines Carrier Proteins MAP Kinase Kinase Kinase 5 RNA, Small Interfering Glycogen Synthase Kinases Mitogen-Activated Protein Kinase 9 Deoxycytidine Kinase Janus Kinase 3 TYK2 Kinase Transcription Factors Receptor, Epidermal Growth Factor A Kinase Anchor Proteins Proteins Maleimides 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Checkpoint Kinase 2 NF-kappa B Diglycerides Imidazoles Membrane Proteins Butadienes DNA-Activated Protein Kinase Lymphocyte Specific Protein Tyrosine Kinase p56(lck)Death-Associated Protein Kinases Isoquinolines Cyclin-Dependent Kinase Inhibitor p21 Phorbol 12,13-Dibutyrate DNA Primers Mitogen-Activated Protein Kinase 7 Epidermal Growth Factor Proto-Oncogene Proteins pp60(c-src)Acetate Kinase Nuclear Proteins Proto-Oncogene Proteins c-abl beta-Adrenergic Receptor Kinases Nitriles Phorbol Esters Piperazines Phosphothreonine Calcium-Calmodulin-Dependent Protein Kinase Kinase Proto-Oncogene Proteins c-fyn Insulin Mitogen-Activated Protein Kinase 14 DNA, Complementary Guanylate Kinase Calcium-Calmodulin-Dependent Protein Kinase Type 1 Calmodulin ZAP-70 Protein-Tyrosine Kinase Carbazoles Cyclins Phosphoric Monoester Hydrolases Genistein Saccharomyces cerevisiae Proteins Cyclic AMP-Dependent Protein Kinase Type II CDC28 Protein Kinase, S cerevisiae Type C Phospholipases Antineoplastic Agents Peptides Actins G-Protein-Coupled Receptor Kinase 1 Protein Phosphatase 1 Uridine Kinase Interleukin-1 Receptor-Associated Kinases DNA Calcium-Calmodulin-Dependent Protein Kinase Type 4 Multienzyme Complexes G-Protein-Coupled Receptor Kinase 2 Benzamides Tumor Suppressor Proteins G-Protein-Coupled Receptor Kinases Phosphatidylinositol Phosphates

Analytical, Diagnostic and Therapeutic Techniques and Equipment13

Transfection Blotting, Western Immunoblotting Precipitin Tests Models, Biological Cloning, Molecular Mutagenesis, Site-Directed Peptide Mapping Electrophoresis, Polyacrylamide Gel Sequence Alignment Reverse Transcriptase Polymerase Chain Reaction Models, Molecular Microscopy, Fluorescence

Phenomena and Processes39

MAP Kinase Signaling System Phosphorylation Signal Transduction Protein Binding Kinetics Mutation Transfection Enzyme Activation Substrate Specificity Base Sequence Apoptosis Amino Acid Sequence Protein Structure, Tertiary Binding Sites Sequence Homology, Amino Acid Gene Expression Regulation, Enzymologic Cell Division Cell Cycle Dose-Response Relationship, Drug Gene Expression Regulation Time Factors Cell Proliferation Transcription, Genetic Down-Regulation Cell Survival Protein Transport Mitosis src Homology Domains Gene Expression Molecular Weight Up-Regulation Cell Differentiation Cell Movement Catalytic Domain Protein Processing, Post-Translational RNA Interference Promoter Regions, Genetic Cell Adhesion Amino Acid Motifs

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Anatomy Organisms Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science

Phosphatidylinositol 3-Kinases MAP Kinase Signaling System Protein Kinases Protein-Serine-Threonine Kinases Protein Kinase Inhibitors Calcium-Calmodulin-Dependent Protein Kinases src-Family Kinases Protein Kinase C p38 Mitogen-Activated Protein Kinases Cyclic AMP-Dependent Protein Kinases Mitogen-Activated Protein Kinase 1 p21-Activated Kinases Mitogen-Activated Protein Kinase Kinases JNK Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinase 3 Protein-Tyrosine Kinases Creatine Kinase CDC2 Protein Kinase Cyclin-Dependent Kinases MAP Kinase Kinase Kinases eIF-2 Kinase Casein Kinase II Casein Kinases Pyruvate Kinase Ribosomal Protein S6 Kinases Phosphorylation MAP Kinase Kinase 1 Receptor Protein-Tyrosine Kinases Thymidine Kinase Extracellular Signal-Regulated MAP Kinases MAP Kinase Kinase 4 1-Phosphatidylinositol 4-Kinase Phosphotransferases (Alcohol Group Acceptor)Mitogen-Activated Protein Kinases CDC2-CDC28 Kinases I-kappa B Kinase Glycogen Synthase Kinase 3 Aurora Kinases rho-Associated Kinases Isoenzymes Protein Kinase C-delta Protein Kinase C-alpha Signal Transduction Proto-Oncogene Proteins Diacylglycerol Kinase AMP-Activated Protein Kinases Protein Binding Kinetics Proto-Oncogene Proteins c-akt Focal Adhesion Kinase 1 Mutation Transfection Myosin-Light-Chain Kinase Janus Kinase 2 Focal Adhesion Protein-Tyrosine Kinases Enzyme Activation Molecular Sequence Data Blotting, Western Ribosomal Protein S6 Kinases, 90-kDa Tyrosine Intracellular Signaling Peptides and Proteins Phosphoproteins Protein Kinase C-epsilon MAP Kinase Kinase Kinase 1 Substrate Specificity Calcium-Calmodulin-Dependent Protein Kinase Type 2 Protein Kinase C beta Tetradecanoylphorbol Acetate MAP Kinase Kinase 2 Cyclin-Dependent Kinase 2 Serine Cyclic GMP-Dependent Protein Kinases Androstadienes Base Sequence TOR Serine-Threonine Kinases Cell Line Apoptosis Cyclin-Dependent Kinase 5 Amino Acid Sequence Recombinant Proteins Phosphoglycerate Kinase Cell Line, Tumor Protein Structure, Tertiary Chromones Phosphorylase Kinase Arginine Kinase Recombinant Fusion Proteins Binding Sites Cell Cycle Proteins Nucleoside-Phosphate Kinase MAP Kinase Kinase 6 Morpholines Casein Kinase I MAP Kinase Kinase 3 Mitogen-Activated Protein Kinase 8 Aurora Kinase A 3-Phosphoinositide-Dependent Protein Kinases Focal Adhesion Kinase 2 Cyclic AMP Tumor Cells, Cultured

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