Negatively regulates cell proliferation. Medical search. Frequent questions

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Anatomy42

Cells, Cultured Cell Line, Tumor Cell Line Tumor Cells, Cultured Epithelial Cells T-Lymphocytes Stem Cells Fibroblasts Muscle, Smooth, Vascular Myocytes, Smooth Muscle Endothelial Cells Endothelium, Vascular B-Lymphocytes NIH 3T3 Cells Epithelium Cell Nucleus CD4-Positive T-Lymphocytes Cell Line, Transformed Liver Keratinocytes Intestinal Mucosa Neural Stem Cells Bone Marrow Cells Spleen Glomerular Mesangium Hematopoietic Stem Cells Extracellular Matrix Embryo, Mammalian 3T3 Cells HeLa Cells Tunica Intima Aorta Clone Cells Stromal Cells Lymphocytes Colon Epidermis Neurons HEK293 Cells Skin Macrophages Osteoblasts

Organisms13

Mice, Inbred C57BL Mice, Knockout Mice, Nude Mice, Transgenic Mice, Inbred BALB C Rats, Sprague-Dawley Rats, Inbred F344 Rats, Wistar Mice, SCID Cattle Mice, Mutant Strains Animals, Newborn Mice, Inbred Strains

Diseases13

Cell Transformation, Neoplastic Hyperplasia Breast Neoplasms Disease Models, Animal Neovascularization, Pathologic Neoplasm Invasiveness Neoplasms Colonic Neoplasms Prostatic Neoplasms Liver Neoplasms Lung Neoplasms Carcinoma, Hepatocellular Adenocarcinoma

Chemicals and Drugs100

Bromodeoxyuridine RNA, Messenger Proliferating Cell Nuclear Antigen Ki-67 Antigen RNA, Small Interfering Cyclin D1 Thymidine Transcription Factors Proto-Oncogene Proteins c-akt Cyclin-Dependent Kinase Inhibitor p27 Cell Cycle Proteins DNA Growth Inhibitors Enzyme Inhibitors Extracellular Signal-Regulated MAP Kinases DNA-Binding Proteins Mitogens Proto-Oncogene Proteins Proto-Oncogene Proteins c-myc Cyclin-Dependent Kinase Inhibitor p21 Antineoplastic Agents Protein-Serine-Threonine Kinases Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinase 1 Platelet-Derived Growth Factor Nuclear Proteins Fibroblast Growth Factor 2 Growth Substances Phosphatidylinositol 3-Kinases Transforming Growth Factor beta Interleukin-2 Tumor Suppressor Protein p53 Tumor Suppressor Proteins Recombinant Proteins Mitogen-Activated Protein Kinases Epidermal Growth Factor Cyclins MicroRNAs Neoplasm Proteins Trans-Activators beta Catenin Retinoblastoma Protein Vascular Endothelial Growth Factor A Antigens, CD Cytokines Receptor, Epidermal Growth Factor DNA Primers Intercellular Signaling Peptides and Proteins Oligonucleotides, Antisense Membrane Proteins Intracellular Signaling Peptides and Proteins STAT3 Transcription Factor Carcinogens Insulin-Like Growth Factor I Antibodies, Monoclonal TOR Serine-Threonine Kinases Cyclin-Dependent Kinases Cyclin E Homeodomain Proteins Estradiol Proteins Culture Media, Serum-Free Repressor Proteins Carrier Proteins Protein-Tyrosine Kinases Protein Kinase Inhibitors Cyclin D Culture Media, Conditioned Proto-Oncogene Proteins c-sis Interferon-gamma Cyclin D2 Recombinant Fusion Proteins Antimetabolites Protein Isoforms Collagen Proto-Oncogene Proteins c-bcl-2 NF-kappa B Cyclin A Cyclin-Dependent Kinase 2 Caspase 3 Hedgehog Proteins Cyclin-Dependent Kinase 4 Phosphoproteins Wnt Proteins E2F1 Transcription Factor Flavonoids ras Proteins Angiogenesis Inhibitors Receptors, Cell Surface Adaptor Proteins, Signal Transducing Receptors, Interleukin-2 Antigens, CD3 Plant Extracts E2F Transcription Factors Estrogens Estrogen Receptor alpha Tetrazolium Salts Receptor Protein-Tyrosine Kinases Receptor, IGF Type 1 Tumor Markers, Biological

Analytical, Diagnostic and Therapeutic Techniques and Equipment33

Immunohistochemistry Blotting, Western Lymphocyte Activation Reverse Transcriptase Polymerase Chain Reaction Flow Cytometry Transfection Cell Count Gene Knockdown Techniques Disease Models, Animal Models, Biological Mitotic Index Gene Expression Profiling In Situ Nick-End Labeling Xenograft Model Antitumor Assays Real-Time Polymerase Chain Reaction Cell Culture Techniques In Situ Hybridization Transplantation, Heterologous Coculture Techniques Neoplasm Transplantation Oligonucleotide Array Sequence Analysis Immunoblotting Culture Media, Serum-Free Culture Media, Conditioned Fluorescent Antibody Technique Immunoenzyme Techniques Organ Size Cell Separation Microscopy, Fluorescence Organ Culture Techniques Tumor Burden Blotting, Northern Immunoprecipitation

Phenomena and Processes56

Cell Proliferation Cell Division Signal Transduction Apoptosis Cell Cycle Cell Differentiation Cell Movement Cell Survival Lymphocyte Activation Phosphorylation Gene Expression Regulation, Neoplastic Cell Growth Processes Down-Regulation Gene Expression Regulation Dose-Response Relationship, Drug Transfection Time Factors Gene Expression Up-Regulation RNA Interference Cell Count Enzyme Activation Gene Expression Regulation, Developmental Base Sequence MAP Kinase Signaling System G1 Phase Phenotype Mutation Cell Adhesion S Phase Mitosis Transcription, Genetic Protein Binding Amino Acid Sequence Wound Healing Cell Cycle Checkpoints Neurogenesis Regeneration Promoter Regions, Genetic Gene Silencing G1 Phase Cell Cycle Checkpoints G0 Phase Neovascularization, Physiologic Drug Synergism Cell Death Morphogenesis DNA Replication Liver Regeneration Cell Communication Kinetics Autocrine Communication Cell Aging Genes, myc Organ Size Transcriptional Activation Cell Lineage

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Cell Proliferation Cell Division Cells, Cultured Signal Transduction Cell Line, Tumor Apoptosis Cell Cycle Cell Differentiation Bromodeoxyuridine RNA, Messenger Cell Movement Cell Survival Immunohistochemistry Cell Line Blotting, Western Proliferating Cell Nuclear Antigen Lymphocyte Activation Phosphorylation Mice, Inbred C57BL Ki-67 Antigen Reverse Transcriptase Polymerase Chain Reaction Tumor Cells, Cultured Gene Expression Regulation, Neoplastic RNA, Small Interfering Cell Growth Processes Down-Regulation Gene Expression Regulation Epithelial Cells Flow Cytometry Dose-Response Relationship, Drug Mice, Knockout Transfection Cyclin D1 T-Lymphocytes Stem Cells Time Factors Thymidine Mice, Nude Gene Expression Up-Regulation Mice, Transgenic Fibroblasts Transcription Factors RNA Interference Proto-Oncogene Proteins c-akt Cell Count Muscle, Smooth, Vascular Cyclin-Dependent Kinase Inhibitor p27 Mice, Inbred BALB C Molecular Sequence Data Cell Transformation, Neoplastic Enzyme Activation Hyperplasia Cell Cycle Proteins DNA Growth Inhibitors Enzyme Inhibitors Extracellular Signal-Regulated MAP Kinases Myocytes, Smooth Muscle Rats, Sprague-Dawley DNA-Binding Proteins Mitogens Gene Knockdown Techniques Proto-Oncogene Proteins Proto-Oncogene Proteins c-myc Cyclin-Dependent Kinase Inhibitor p21 Antineoplastic Agents Gene Expression Regulation, Developmental Protein-Serine-Threonine Kinases Base Sequence MAP Kinase Signaling System Mitogen-Activated Protein Kinase 3 G1 Phase Breast Neoplasms Phenotype Disease Models, Animal Mutation Mitogen-Activated Protein Kinase 1 Models, Biological Platelet-Derived Growth Factor Nuclear Proteins Fibroblast Growth Factor 2 Cell Adhesion Growth Substances Phosphatidylinositol 3-Kinases Transforming Growth Factor beta Neovascularization, Pathologic Interleukin-2 S Phase Tumor Suppressor Protein p53 Tumor Suppressor Proteins Recombinant Proteins Mitogen-Activated Protein Kinases Mitosis Mitotic Index Gene Expression Profiling Epidermal Growth Factor Cyclins Endothelial Cells In Situ Nick-End Labeling

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