NecrosisTumor Necrosis Factor-alphaApoptosisCaspasesApoptosis Regulatory ProteinsCaspase 3Proto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsReceptors, Tumor Necrosis FactorDNA FragmentationIn Situ Nick-End Labelingbcl-2-Associated X ProteinCell Line, TumorCell SurvivalX-Linked Inhibitor of Apoptosis ProteinSignal TransductionCells, CulturedCASP8 and FADD-Like Apoptosis Regulating ProteinApoptosis Inducing FactorCaspase InhibitorsCaspase 9Caspase 8Enzyme ActivationMitochondriaTumor Cells, CulturedFas Ligand ProteinTumor Suppressor Protein p53Cell LineCytochromes cbcl-X ProteinBlotting, WesternTNF-Related Apoptosis-Inducing LigandCell ProliferationAnnexin A5Flow CytometryNF-kappa BAmino Acid Chloromethyl KetonesReceptors, Tumor Necrosis Factor, Type IICysteine Proteinase InhibitorsRNA, MessengerAntineoplastic AgentsProto-Oncogene ProteinsDose-Response Relationship, DrugPoly(ADP-ribose) PolymerasesEnzyme InhibitorsCell CycleTransfectionCell DeathReactive Oxygen SpeciesMice, Inbred C57BLCell DivisionTime FactorsJurkat CellsMembrane GlycoproteinsDown-RegulationRNA, Small InterferingUp-RegulationPhosphorylationReverse Transcriptase Polymerase Chain ReactionCaspase 7HL-60 CellsMembrane Potential, MitochondrialCytokinesGene Expression RegulationMice, KnockoutReceptors, TNF-Related Apoptosis-Inducing LigandTumor Necrosis FactorsGenes, bcl-2ImmunohistochemistryDrug SynergismFat NecrosisCytochrome c Groupbcl-2 Homologous Antagonist-Killer ProteinProto-Oncogene Proteins c-aktBH3 Interacting Domain Death Agonist ProteinGene ExpressionDNA DamageRecombinant ProteinsCarrier ProteinsMyeloid Cell Leukemia Sequence 1 ProteinStaurosporineDisease Models, AnimalOxidative StressCeramidesProtein-Serine-Threonine KinasesFas-Associated Death Domain ProteinGene Expression Regulation, NeoplasticMitogen-Activated Protein KinasesInterleukin-1HeLa CellsLipopolysaccharidesFemur Head NecrosisMacrophagesRats, Sprague-DawleyFibroblastsbcl-Associated Death ProteinKidney Papillary NecrosisMembrane ProteinsEpithelial CellsAntineoplastic Agents, Phytogenic