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Anatomy26

Oocytes Ranvier's Nodes Neurons Ganglia, Spinal Cell Line Cells, Cultured Cell Membrane Axons Myocardium Cell Line, Tumor HEK293 Cells Heart Neurons, Afferent Tumor Cells, Cultured Kidney Muscle, Skeletal Brain Sensory Receptor Cells Muscles Synaptosomes CHO Cells Nociceptors Myocytes, Cardiac Kidney Tubules, Collecting Heart Conduction System Sciatic Nerve

Organisms21

Xenopus laevis Xenopus Rats, Sprague-Dawley Scorpions Decapodiformes Cockroaches Rats, Wistar Guinea Pigs Cricetinae Rabbits Electrophorus Sea Anemones Spiders Dogs Plasmodium falciparum Animals, Newborn Rana pipiens Mice, Inbred C57BL Mice, Knockout Rana esculenta Periplaneta

Diseases10

Erythromelalgia Myotonia Channelopathies Brugada Syndrome Long QT Syndrome Hypokalemic Periodic Paralysis Epilepsies, Myoclonic Paralyses, Familial Periodic Neuroma Paralysis, Hyperkalemic Periodic

Chemicals and Drugs139

Sodium Channels Sodium Channel Blockers NAV1.8 Voltage-Gated Sodium Channel NAV1.7 Voltage-Gated Sodium Channel NAV1.2 Voltage-Gated Sodium Channel NAV1.5 Voltage-Gated Sodium Channel Ion Channels Sodium Epithelial Sodium Channels NAV1.3 Voltage-Gated Sodium Channel NAV1.1 Voltage-Gated Sodium Channel NAV1.9 Voltage-Gated Sodium Channel NAV1.4 Voltage-Gated Sodium Channel Voltage-Gated Sodium Channels NAV1.6 Voltage-Gated Sodium Channel Calcium Channels Sodium Channel Agonists Tetrodotoxin Voltage-Gated Sodium Channel Blockers Saxitoxin Potassium Channels, Inwardly Rectifying Batrachotoxins Calcium Channel Blockers Potassium Channel Blockers Chloride Channels Potassium Channels, Voltage-Gated Scorpion Venoms Veratridine Voltage-Gated Sodium Channel beta-1 Subunit Calcium Channels, L-Type Potassium Shaker Superfamily of Potassium Channels Voltage-Gated Sodium Channel beta-3 Subunit Lidocaine Epithelial Sodium Channel Blockers KATP Channels Potassium Channels, Calcium-Activated Amiloride Voltage-Gated Sodium Channel beta-2 Subunit Nerve Tissue Proteins Large-Conductance Calcium-Activated Potassium Channels Antineoplastic Agents Calcium Acid Sensing Ion Channels Kv1.2 Potassium Channel Voltage-Gated Sodium Channel beta-4 Subunit Pyrethrins Cyclic Nucleotide-Gated Cation Channels Calcium Channels, T-Type Calcium Channels, N-Type Mexiletine Conotoxins Degenerin Sodium Channels Protein Subunits TRPC Cation Channels Ether-A-Go-Go Potassium Channels Semustine Neurotoxins Muscle Proteins Sodium, Dietary Anesthetics, Local Kv1.1 Potassium Channel Sodium Chloride RNA, Messenger Epithelial Sodium Channel Agonists Doxorubicin Kv1.3 Potassium Channel Calcium Channel Agonists TRPV Cation Channels Spider Venoms Barium TRPM Cation Channels KCNQ1 Potassium Channel Cnidarian Venoms Protein Isoforms Oxocins Tetraethylammonium KCNQ Potassium Channels Marine Toxins Kv1.5 Potassium Channel Chlorides Recombinant Proteins Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels Potassium Channels KCNQ2 Potassium Channel Kv1.4 Potassium Channel Shaw Potassium Channels Shab Potassium Channels Small-Conductance Calcium-Activated Potassium Channels Ankyrins RNA, Complementary Adenosine Triphosphate Lipid Bilayers Amphibian Proteins Semicarbazones Transient Receptor Potential Channels Shal Potassium Channels Cesium Acetanilides P-Glycoprotein Insecticides Anti-Arrhythmia Agents Cisplatin Cations Enzyme Inhibitors Large-Conductance Calcium-Activated Potassium Channel alpha Subunits Ciguatoxins Tetraethylammonium Compounds Antimalarials G Protein-Coupled Inwardly-Rectifying Potassium Channels Ryanodine Receptor Calcium Release Channel Verapamil ATP-Binding Cassette Transporters DNA, Complementary Membrane Proteins Calcium Channels, P-Type Mollusk Venoms KCNQ3 Potassium Channel Peptides Vinca Alkaloids Contactins Aldosterone Daunorubicin Nifedipine Multidrug Resistance-Associated Proteins Glyburide Etoposide Recombinant Fusion Proteins Benzocaine Voltage-Dependent Anion Channels Intermediate-Conductance Calcium-Activated Potassium Channels Calcium Channels, Q-Type Veratrine Receptors, Drug Calcium Channels, R-Type Mitolactol Ions Quinine DNA Primers

Analytical, Diagnostic and Therapeutic Techniques and Equipment18

Sensitivity and Specificity Patch-Clamp Techniques Drug Screening Assays, Antitumor Parasitic Sensitivity Tests Models, Biological Inhibitory Concentration 50 Transfection Electric Stimulation Mutagenesis, Site-Directed Amino Acid Substitution Models, Molecular Tumor Stem Cell Assay Reverse Transcriptase Polymerase Chain Reaction Blotting, Western Drug Evaluation, Preclinical Cloning, Molecular Polymerase Chain Reaction Reproducibility of Results

Phenomena and Processes37

Ion Channel Gating Membrane Potentials Sensitivity and Specificity Electric Conductivity Action Potentials Drug Resistance Kinetics Mutation Amino Acid Sequence Dose-Response Relationship, Drug Drug Resistance, Neoplasm Time Factors Inhibitory Concentration 50 Protein Structure, Tertiary Ion Transport Transfection Amino Acid Substitution Binding Sites Cell Survival Hydrogen-Ion Concentration Mutation, Missense Structure-Activity Relationship Biophysical Phenomena Base Sequence Drug Resistance, Multiple Phenotype Protein Binding Electrophysiological Phenomena Gene Expression Cell Membrane Permeability Protein Conformation Sequence Homology, Amino Acid Signal Transduction Phosphorylation Point Mutation Algorithms Protein Structure, Secondary

Disciplines and Occupations3

Electrophysiology Biophysics Mathematics

Technology, Industry, Agriculture1

Information Science4

Molecular Sequence Data Amino Acid Sequence Base Sequence Algorithms

Health Care2

Sensitivity and Specificity Reproducibility of Results

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Technology, Industry, Agriculture Information Science Health Care

Sodium Channels Sodium Channel Blockers NAV1.8 Voltage-Gated Sodium Channel NAV1.7 Voltage-Gated Sodium Channel NAV1.2 Voltage-Gated Sodium Channel NAV1.5 Voltage-Gated Sodium Channel Ion Channels Sodium Epithelial Sodium Channels NAV1.3 Voltage-Gated Sodium Channel NAV1.1 Voltage-Gated Sodium Channel Ion Channel Gating NAV1.9 Voltage-Gated Sodium Channel NAV1.4 Voltage-Gated Sodium Channel Voltage-Gated Sodium Channels NAV1.6 Voltage-Gated Sodium Channel Calcium Channels Membrane Potentials Sensitivity and Specificity Sodium Channel Agonists Electrophysiology Tetrodotoxin Patch-Clamp Techniques Voltage-Gated Sodium Channel Blockers Saxitoxin Potassium Channels, Inwardly Rectifying Batrachotoxins Calcium Channel Blockers Potassium Channel Blockers Electric Conductivity Oocytes Chloride Channels Potassium Channels, Voltage-Gated Scorpion Venoms Action Potentials Xenopus laevis Drug Resistance Kinetics Veratridine Voltage-Gated Sodium Channel beta-1 Subunit Calcium Channels, L-Type Molecular Sequence Data Mutation Potassium Drug Screening Assays, Antitumor Xenopus Amino Acid Sequence Shaker Superfamily of Potassium Channels Voltage-Gated Sodium Channel beta-3 Subunit Dose-Response Relationship, Drug Lidocaine Ranvier's Nodes Neurons Epithelial Sodium Channel Blockers Ganglia, Spinal KATP Channels Potassium Channels, Calcium-Activated Amiloride Drug Resistance, Neoplasm Voltage-Gated Sodium Channel beta-2 Subunit Erythromelalgia Cell Line Time Factors Nerve Tissue Proteins Cells, Cultured Large-Conductance Calcium-Activated Potassium Channels Antineoplastic Agents Rats, Sprague-Dawley Calcium Parasitic Sensitivity Tests Acid Sensing Ion Channels Kv1.2 Potassium Channel Voltage-Gated Sodium Channel beta-4 Subunit Pyrethrins Cyclic Nucleotide-Gated Cation Channels Calcium Channels, T-Type Calcium Channels, N-Type Cell Membrane Axons Mexiletine Models, Biological Conotoxins Inhibitory Concentration 50 Degenerin Sodium Channels Protein Subunits Scorpions Protein Structure, Tertiary Decapodiformes TRPC Cation Channels Ion Transport Ether-A-Go-Go Potassium Channels Cockroaches Transfection Semustine Neurotoxins Electric Stimulation Myotonia Muscle Proteins Sodium, Dietary Anesthetics, Local

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