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HydrogelHydrogelsBiocompatible MaterialsContact Lenses, HydrophilicPolyethylene GlycolsKiller Cells, NaturalTissue EngineeringTissue ScaffoldsPolyvinyl AlcoholHexuronic AcidsMaterials TestingGlucuronic AcidGelatinAlginatesSiliconesContact Lenses, Extended-WearAcrylic ResinsPolyhydroxyethyl MethacrylatePoloxamerAcrylamidesCells, ImmobilizedPolyestersRheologyPorosityContact LensesMicrospheresChitosanAcrylatesDelayed-Action PreparationsElastic ModulusMethacrylatesMechanical PhenomenaCell Culture TechniquesHyaluronic AcidBandages, HydrocolloidNanofibersBiomimetic MaterialsDrug Delivery SystemsContact Lens SolutionsMicroscopy, Electron, ScanningInjectionsPolymersDrug CarriersSilicone ElastomersAbsorbable ImplantsCross-Linking ReagentsBiomimeticsMesenchymal Stromal CellsViscosityBiological ProductsSodium BenzoateTissue AdhesivesBiofoulingParticle SizeCell SurvivalSurface PropertiesImplants, ExperimentalBandagesSkin Physiological ProcessesCells, CulturedDextransChemistry, PharmaceuticalTissue Culture TechniquesExtracellular MatrixCorneaPolyglycolic AcidPolymethacrylic AcidsPolymerization
Hybrid hydrogelsInjectableSupramolecular hydrogelsSpecial hydrogelTissuesBiomedical applicationsStimuli-responsiveTissueBiocompatibilityRegenerative medicineGelsContact lensesMimicHyaluronic acidBiocompatible2018SiliconeSynthetic polymersPhysicochemicalResearchersMaskFibersPeptideCollagenBiologicalHydrophilicNanofiberPolymers that can absorbExtracellular matrixInteractionsInnovativeChitinToughnessSynthesisSurfacesChitosanPolyacrylamidePolymer chainsMechanical strengthAmino acidsMaterialsPolysaccharidesConsistsMasksFibroblastsLatexMoleculesSkin'sWidelyEnablesBioengineeringDifferentiationVersatileSuitableAdvantagesScientists
Hybrid hydrogels5
  • The current proof-of-concept work should be just the start for exploring many other hybrid hydrogels that could exploit the unique properties of other natural systems. (sciencedaily.com)
  • Montheil T, Echalier C, Martinez J, Subra G, Mehdi A. Inorganic polymerization: an attractive route to biocompatible hybrid hydrogels. (nature.com)
  • Preparation and enhanced mechanical properties of hybrid hydrogels comprising ultralong hydroxyapatite nanowires and sodium alginate. (nature.com)
  • There are three main types of hydrogels based on their origin and composition: natural, synthetic, and hybrid hydrogels. (thewitfire.in)
  • Hybrid hydrogels are composed of both natural and synthetic polymers. (thewitfire.in)
Injectable4
  • Thus, chemists and pharmacologists persistently desire to prepare directed self-assemble hydrogels, referring to self-delivering, self-releasing, stable, injectable and stimuli-responsive hydrogels without any structural modification and delivery cargoes. (nature.com)
  • Here, we demonstrate an injectable filamentous hydrogel depot (FM-depot) engineered for low dosage, sustained delivery of anti-inflammatory nanocarriers. (frontiersin.org)
  • Injectable hydrogels are a class of hydrogels that can be administered through a syringe and needle, forming a gel in situ upon injection. (thewitfire.in)
  • Herein, we develop an injectable and self -healing hydrogel derived from ß- chitin which consists of an amino group of quaternized ß- chitin (QC) and an aldehyde group of oxidized dextran (OD) between the dynamic Schiff base linkage.it can carry bFGF and SDF-1a and be injected into the vaginal forearm of mice in a non-invasive manner. (bvsalud.org)
Supramolecular hydrogels1
  • In this study, the hydrophobic drug Tanshinone ⅡA (Tan ⅡA) as a therapeutic drug was loaded into naphthalene acetic acid-phenylalanine-phenylalanine-glycine hydrogel (Nap-FFG) to construct the supramolecular hydrogels. (jascoinc.com)
Special hydrogel2
  • The scientists, working in a special hydrogel with properties they can change in a controlled manner, first grew a parent blood vessel from human blood vessel lining cells. (mpg.de)
  • The answer is the polymer used now is a special hydrogel. (psu.edu)
Tissues14
  • Hydrogel dressings can be designed to prevent bacterial infection, retain moisture, promote optimum adhesion to tissues, and satisfy the basic requirements of biocompatibility. (wikipedia.org)
  • Hydrogel wound dressings are designed to have a mechanism for application and removal which minimizes further trauma to tissues. (wikipedia.org)
  • Hydrogels are effective biomaterials for wound dressings and tissue engineering because they exchange fluid, hydrating necrotic tissues. (wikipedia.org)
  • Among different types of scaffolds, polymeric hydrogel scaffolds have received considerable attention because of their biocompatibility and structural similarity to native tissues. (mdpi.com)
  • The natural abilities of squid tissues and the creativity of chemists combine to take hydrogel research in new directions. (sciencedaily.com)
  • Researchers at Hokkaido University in Japan have combined natural squid tissues with synthetic polymers to develop a strong and versatile hydrogel that mimics many of the unique properties of biological tissues. (sciencedaily.com)
  • Natural biological tissues exhibit unique properties essential for their functions, which researchers are seeking to replicate in hydrogels. (sciencedaily.com)
  • Unlike the natural tissues that researchers wish to mimic, most synthetic hydrogels have uniform properties in all directions and are structurally weak. (sciencedaily.com)
  • By combining the properties of tissues derived from squid with synthetic polymers, we have demonstrated a hybrid strategy that serves as a general method for preparing hydrogels with useful hierarchical anisotropy and also toughness," says polymer scientist Tasuku Nakajima of the Hokkaido University team. (sciencedaily.com)
  • Synthetic materials could be suitable as scaffolding for tissue because, unlike natural tissues, they remain stable in the organism long enough for the body to form new natural structures. (mpg.de)
  • Moreover, the effect of all these factors is linked in natural tissues and varies from organ to organ," Britta Trappmann explains. (mpg.de)
  • In one channel, the scientists seed endothelial cells, which line blood vessels in natural tissues. (mpg.de)
  • When this has happened, the scientists deliver a growth factor cocktail of molecules that drive blood vessel growth in natural tissues through the second channel, whereupon the endothelial cells migrate into the hydrogel. (mpg.de)
  • The company has created a way to encapsulate a wide range of pharmaceuticals within its hydrogel to provide targeted, sustained delivery of therapeutic levels of drugs to ocular tissues. (ophthalmologytimes.com)
Biomedical applications8
  • Self-assembling natural drug hydrogels formed without structural modification and able to act as carriers are of interest for biomedical applications. (nature.com)
  • Unique molecular interactions between graphene derivatives and various small or macromolecules enable the fabrication of various functional hydrogels appropriate for different biomedical applications. (nature.com)
  • In this mini-review, we highlight the recent progress in GO-incorporated hydrogels for biomedical applications while focusing on their specific uses as mechanically strong materials, electrically conductive scaffolds/electrodes, and high-performance drug delivery vehicles. (nature.com)
  • Recent developments in tough hydrogels for biomedical applications. (nature.com)
  • Hydrogels for biomedical applications. (nature.com)
  • Chai Q, Jiao Y, Yu X. Hydrogels for biomedical applications: their characteristics and the mechanisms behind them. (nature.com)
  • Biomedical applications of hydrogels: a review of patents and commercial products. (nature.com)
  • Chitin is a natural biopolymer have been used for several biomedical applications due to its biodegradability and biocompatibility. (amrita.edu)
Stimuli-responsive2
  • Some hydrogel dressings have incorporated stimuli-responsive nitric oxide-releasing agents and other antimicrobial agents. (wikipedia.org)
  • Hydrogels have been widely studied for drug delivery applications due to their unique characteristics, such as high water content, tunable mechanical properties, and stimuli-responsive behavior. (thewitfire.in)
Tissue9
  • Chemical and heat treatment of thin slices of the defrosted squid tissue mixed with polyacrylamide polymer molecules initiated formation of the cross-linked hybrid hydrogel. (sciencedaily.com)
  • Song F, Li X, Wang Q, Liao L, Zhang C. Nanocomposite hydrogels and their applications in drug delivery and tissue engineering. (nature.com)
  • The researchers first enriched the hydrogel tissue framework with varying amounts of peptides that activate a certain type of adhesion molecule found in the membrane of endothelial cells called integrins. (mpg.de)
  • Hydrogels possess a comfortable degree of flexibility similar to natural tissue, due to their significant water content. (ophthalmologytimes.com)
  • There is a need for biocompatible, biodegradable, 3-D printable and stable hydrogels especially in the areas of tissue engineering, drug delivery, bio-sensing technologies and antimicrobial coatings. (dcu.ie)
  • A more recent approach proposes tissue engineering the electrode interface through the use of encapsulated neurons within hydrogel coatings. (frontiersin.org)
  • Owing to their unique properties, hydrogels have found applications in a wide range of fields, including tissue engineering, wound healing , drug delivery systems, and contact lenses. (thewitfire.in)
  • Natural hydrogels have been extensively used in drug delivery and tissue engineering applications due to their excellent biocompatibility and biodegradability. (thewitfire.in)
  • Here, a tissue-specific hybrid bioink is described, composed of a natural polymer, alginate, reinforced with extracellular matrix derived from decellularized tissue (rECM). (lu.se)
Biocompatibility1
  • These gels combine the advantages of natural gels, such as biocompatibility and biodegradability, with the tunable properties of synthetic gels. (thewitfire.in)
Regenerative medicine1
  • We think the regenerative medicine approach based on bFGF/SDF-1/ chitin hydrogel may be an effective non-surgical approach to combat clinical SUI. (bvsalud.org)
Gels2
  • A lack of knowledge about natural drug gels limits there current application. (nature.com)
  • Hüma energy gels combine 100% all-natural ingredients and are made with real fruit, making Hüma the best-tasting energy gels on the market. (tcrunningco.com)
Contact lenses3
  • Similarly, three types of natural amino acids, including serine, aspartic acid and histidine, modified silicone hydrogel contact lenses exhibited excellent hydrophilicity and non-damage to the rabbit's eyes, but only serine modified zwitterionic contact lens showed superior protein fouling resistance compared with the current commercial hydrogel contact lens, which may have great potential application in ophthalmology. (polymer.cn)
  • Vellica Gray (2pcs) (Silicone Hydrogel) Color Contact Lenses Lensvery Vellica circle lenses are superior in terms of both comfort and design! (lurube.com)
  • Some examples of these minor polymers include breathable clothing made from gore-tex, hydrogels found in contact lenses, in babies nappies, and finally tooth fillings. (psu.edu)
Mimic2
  • Hydrogel dressings mimic the cross-linked 3D network of extracellular matrix fibers in human skin. (wikipedia.org)
  • In order to mimic the natural environment of cells, many additional biomolecules and cells would have to be integrated into the model system in later steps - these may be signaling proteins, immune cells or cells to stabilize the blood vessels. (mpg.de)
Hyaluronic acid3
  • With added vitamin C, hyaluronic acid and niacinamide, this potent retinol serum is formulated to support the skin's natural exfoliation process, stimulate healthy collagen production and soothe and hydrate the skin. (vitacost.com)
  • This pioneering hydrogel sets a new benchmark in the field, containing fully defined components, including medical grade collagens, laminin-511 E8 fragments, and hyaluronic acid. (labx.com)
  • There are several reports of HRP crosslinked tyramine modified natural polymers such as chitosan, hyaluronic acid. (dcu.ie)
Biocompatible1
  • Natural hydrogels are derived from biological sources and are biodegradable, biocompatible, and often possess cell-adhesive properties. (thewitfire.in)
20181
Silicone6
  • In this report, protein repelling silicone hydrogels with improved hydrophilicity were prepared by photo-polymerization of silicone-containing monomer and glycidyl methacrylate followed by grafting zwitterionic amino acids. (polymer.cn)
  • The grafted silicone hydrogels possessed excellent hydrophilic surfaces due to the enrichment of amino acids, which was confirmed by attenuated total reflectance Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, contact angle, and equilibrium water content measurements. (polymer.cn)
  • Remarkable resistance to bovine serum albumin and lysozyme fouling was observed for the silicone hydrogels immobilized with neutrally charged amino acids because of the formation of zwitterionic surfaces with pairs of protonated secondary ammonium cations and deprotonated carboxyl anions. (polymer.cn)
  • Meanwhile, the silicone hydrogels grafted with positively or negatively charged amino acids were able to repulse same charged protein with reduced deposition and attract oppositely charged protein with increased adsorption. (polymer.cn)
  • Preliminary cytotoxicity test indicated that the zwitterionic silicone hydrogels were non-cytotoxic. (polymer.cn)
  • At Lensvery all of our circle lenses are made with FDA approved silicone hydrogel which provides the highest oxygen transmissibility and is considered one of the most comfortable materials on the market today! (lurube.com)
Synthetic polymers1
Physicochemical1
  • The high water content of hydrogels can help to solubilize hydrophilic drugs, while their tunable properties allow for the incorporation of various drugs with different physicochemical characteristics. (thewitfire.in)
Researchers6
  • Now, researchers reporting in ACS' Nano Letters have developed a hydrogel that can both cool down electronics, such as cell phone batteries, and convert their waste heat into electricity. (scitechdaily.com)
  • The researchers took advantage of the molecular arrangements within this natural system to build their bio-mimicking gel. (sciencedaily.com)
  • Researchers at the Faculty of Physics at the University of Warsaw, using the liquid crystal elastomer technology originally developed in the LENS Institute in Florence, demonstrated a bio-inspired micro-robot capable of mimicking caterpillar gaits in natural scale. (phys.org)
  • Researchers from the University of Warsaw with colleagues from LESN (Italy) and Cambridge (UK) have now developed a natural-scale, soft caterpillar robot with an opto-mechanical liquid crystalline elastomer monolithic design. (phys.org)
  • Researchers have developed a hydrogel that is stronger and more durable than natural cartilage, making it ideal for use in knee implants. (materialstoday.com)
  • A wearable sensor printed on microbial nanocellulose, a natural polymer, has been created in Brazil by researchers at the University of São Paulo (USP) in São Carlos in collaboration with colleagues at São Paulo State University (UNESP) in Araraquara, the University of Araraquara (UNIARA), the University of Campinas (UNICAMP), and the Brazilian National Nanotechnology Laboratory (LNNano). (medicaldesignbriefs.com)
Mask17
Fibers1
  • Nap-FFG hydrogel fibers crosslinked into a network-like structure by self-assembly of polypeptides and then achieved drug loading. (jascoinc.com)
Peptide2
Collagen1
  • Natural hydrogel dressings are further subdivided into either polysaccharide-based (e.g. alginates) or proteoglycan- and/or protein-based (e.g. collagen). (wikipedia.org)
Biological2
  • Hydrogels are three-dimensional, cross-linked networks of hydrophilic polymers that can absorb and retain large amounts of water or biological fluids. (thewitfire.in)
  • The practice of dentistry is likely to be revolutionized by biological therapies based on growth and differentiation factors that accelerate and/or induce a natural biological regeneration. (bvsalud.org)
Hydrophilic1
  • Hydrogels are three-dimensional networks consisting of chemically or physically cross-linked hydrophilic polymers. (wikipedia.org)
Nanofiber2
Polymers that can absorb1
  • Hydrogels are gelatinous amalgams of cross-linked polymers that can absorb and hold large quantities of water. (carbomer.com)
Extracellular matrix2
Interactions5
  • Here, we report on rhein, a herbal natural product, which is directly self-assembled into hydrogels through noncovalent interactions. (nature.com)
  • Physically cross-linked hydrogel dressings are assembled via ionic interaction, hydrogen bonding, hydrophobic interactions, or crystallization. (wikipedia.org)
  • Hydrogels can be formed through a self-assembly process in which monomers diffuse in solution then form non covalent interactions. (wikipedia.org)
  • citation needed] Hydrogels used in wound dressings can be self-assembled upon addition of divalent metal cations or electrically charged polysaccharides due to electrostatic interactions. (wikipedia.org)
  • The adhesive properties of hydrogels have been shown to be enhanced by addition of positively charged microgels (MR) into the 3D matrix to increase electrostatic and hydrophobic interactions. (wikipedia.org)
Innovative1
  • This innovative hydrogel technology assists in delivering active ingredients, and aids in nutrient absorption for more targeted skin nourishment. (100percentpure.com)
Chitin4
  • By using the calcium solvent system, chitin regenerated hydrogel (RG) was prepared by using α-chitin. (amrita.edu)
  • And also, the swelling hydrogel (SG) was prepared by using β-chitin with water. (amrita.edu)
  • Chitin-based hydrogel loaded with bFGF and SDF-1 for inducing endogenous mesenchymal stem cells homing to improve stress urinary incontinence. (bvsalud.org)
  • This is the first bold attempt in the field of pelvic floor using hydrogel mechanical support combined with MSCs homing and the first application of chitin hydrogel in gynecology . (bvsalud.org)
Toughness1
  • Improving hydrogels' toughness by increasing the dissipative properties of their network. (nature.com)
Synthesis1
Surfaces2
  • Soft implant surfaces should be designed with an eye toward natural, healthy biointerfaces, which use high water content aqueous gel gradients to reduce contact pressures and frictional shear stresses and thus reduce inflammation and discomfort. (rsc.org)
  • To create a double-sided tape that could rapidly join two wet surfaces together, the team drew inspiration from the natural world - specifically, the sticky material that spiders use to capture their prey in wet conditions. (scitechdaily.com)
Chitosan1
  • Hydrogel dressings formed from antimicrobial peptides (AMPs) and chitosan have inherent antimicrobial activity. (wikipedia.org)
Polyacrylamide1
  • The team made a hydrogel consisting of a polyacrylamide framework infused with water and specific ions. (scitechdaily.com)
Polymer chains2
  • The absorption of secretions causes the hydrogel dressing to swell, expanding the cross links in the polymer chains. (wikipedia.org)
  • The hydrogel platform is made of branched polymer chains that are covalently crosslinked, and can be engineered to increase or decrease the crosslink density, which alters their degradation rate. (ophthalmologytimes.com)
Mechanical strength1
  • Graphene and graphene derivatives (e.g., graphene oxide (GO)) have been incorporated into hydrogels to improve the properties (e.g., mechanical strength) of conventional hydrogels and/or develop new functions (e.g., electrical conductivity and drug loading/delivery). (nature.com)
Amino acids1
  • These peptides are short chains of natural amino acids found in all living organisms. (eurekalert.org)
Materials9
  • Hybrid hydrogel dressings incorporate synthetic nanoparticles and natural materials. (wikipedia.org)
  • The role of graphene materials in the final structure of hydrogels. (nature.com)
  • Hydrogels as emerging materials for translational. (nature.com)
  • Mikołaj Rogóż et al, Light-Driven Soft Robot Mimics Caterpillar Locomotion in Natural Scale, Advanced Optical Materials (2016). (phys.org)
  • A new generation of hydrogels is based on cheaper, abundant natural materials. (carbomer.com)
  • The simplicity of the process should enable the production of hydrogels at industrial volumes, promising to break the current cost barrier and make these materials useful in a host of new applications in food and beverage manufacturing as well as other fields. (carbomer.com)
  • And because the hydrogel is composed of materials that are food grade-cellulose and colloidal silica are both used in the food industry-there were no odor or taste issues," Appel says. (carbomer.com)
  • One of the most promising materials that have emerged in this field is hydrogels. (thewitfire.in)
  • College of Chemistry & Molecular Sciences, Wuhan University, Hubei Engineering Center of Natural Polymers-based Medical Materials, Wuhan, 430072, People's Republic of China. (bvsalud.org)
Polysaccharides1
  • Natural dressings incorporating polysaccharides and proteoglycans/proteins form a 3D network using physical cross-linking. (wikipedia.org)
Consists1
  • It consists of a three-dimensional sugar-based hydrogel into which the scientists make two channels using an acupuncture needle. (mpg.de)
Masks2
Fibroblasts2
  • Hydrogel dressings should promote an appropriate microenvironment for angiogenesis, recruitment of fibroblasts, and cellular proliferation. (wikipedia.org)
  • Human skin fibroblasts and lung epithelial cells deposit a cfn-rich natural ECm (nECM) with distinct supramolecular structure, and GAS cells preferentially recognize and attach to this structure, as evidenced by field emission scanning electron microscopy. (cdc.gov)
Latex4
  • All products and packaging are not made with natural rubber latex. (woundsource.com)
  • Does not contain natural latex. (bd.com)
  • The Bardex™ Lubricath™ Foley catheters are 2-way latex catheters with a hydrogel coating. (bd.com)
  • Contains Natural Latex. (bd.com)
Molecules2
  • Despite these endeavors, designing directed self-assemble hydrogels formed by natural small molecules is still a formidable challenge. (nature.com)
  • Through containment, localization, and protection from inflammatory response, the hydrogel expands the utility of therapeutic molecules via more effective and consistent delivery. (ophthalmologytimes.com)
Skin's2
  • Along with it's ability to clean deep within the skin's pores, jojoba oil acts as a natural skin conditioner, helping to control oil production. (belleshop.ch)
  • Minerals and vitamins boost the skin's natural moisture-retaining properties leaving skin looking brighter and more youthful. (belleshop.ch)
Widely1
  • In a bid to do better, Appel's team mixed its hydrogel with a widely used fire retardant and found that the mixtures coated the fuels for far longer than the standard retardant and protected the retardants from being washed away with a subsequent water treatment. (carbomer.com)
Enables2
  • This enables rhein hydrogels to significantly dephosphorylate IκBα, inhibiting the nuclear translocation of p65 at the NFκB signalling pathway in lipopolysaccharide-induced BV2 microglia. (nature.com)
  • Hydrogel technology enables the use of drugs that are known to be efficacious for ocular diseases and conditions when formulated as daily drops or monthly injections, into one-time or several-month dosage forms. (ophthalmologytimes.com)
Bioengineering1
  • The authors acknowledge funding from the National Natural Science Foundation of China, the Henry Samueli School of Engineering and Applied Science at the University of California, Los Angeles ( UCLA ) and the Department of Bioengineering at UCLA. (scitechdaily.com)
Differentiation1
  • Functionalized carbon nanotube and graphene oxide embedded electrically conductive hydrogel synergistically stimulates nerve cell differentiation. (nature.com)
Versatile1
  • Hydrogel polymers present a versatile coating option for electrodes as they can be chemically modified to provide a soft and conductive scaffold. (frontiersin.org)
Suitable1
  • Big Class Gray circle lenses are suitable for all eye colors and will enhance your natural beauty. (lurube.com)
Advantages2
  • And their hydrogel-enhanced retardant had other advantages. (carbomer.com)
  • This article delves into the world of hydrogels, discussing their types, applications in pharmaceutical dosing, advantages, and potential challenges. (thewitfire.in)
Scientists1
  • The scientists then wanted to find out which properties of the hydrogel determine whether the migrating endothelial cells actually form new blood vessels. (mpg.de)