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  • researchers
  • A human protein associated with asthma is key to how hantaviruses infect the lungs and sometimes cause a life-threatening pulmonary condition known as hantavirus pulmonary syndrome (HPS), according to researchers supported by the National Institutes of Health. (nih.gov)
  • Although researchers have made considerable progress in understanding how the immune system causes organ, tissue, and cell injury in autoimmune diseases, much remains to be learned. (nih.gov)
  • Close interaction between clinicians and basic researchers accelerates the discovery, development, and translation of therapies for autoimmune diseases from the lab to use in the clinic. (nih.gov)
  • The Institute also encourages researchers to develop tools and identify biomarkers that allow clinicians to rapidly assess how people respond to therapy and to assist in conducting drug and vaccine clinical trials. (nih.gov)
  • Researchers investigate the puzzling phenomenon of why mosquitoes prefer to bite some people over others in an effort to find new ways to prevent mosquitoes from finding and biting people, and, ultimately, reduce the transmission of mosquito-borne diseases. (nih.gov)
  • vaccines
  • Although smallpox vaccines have been developed and procured for the SNS, they cannot completely prevent disease or attenuate the illness if given too late following exposure. (nih.gov)
  • Vaccines take advantage of your body's natural ability to learn how to combat many disease-causing germs, or microbes, that attack it. (nih.gov)
  • Infections
  • Although the causes of many autoimmune diseases remain unknown, a person's genes in combination with infections and other environmental exposures are likely to play a significant role in disease development. (nih.gov)
  • The destruction of these cells leaves people living with HIV vulnerable to other infections, diseases and other complications. (nih.gov)
  • These abnormalities resulting from this disease lead to recurrent viral infections of the skin and respiratory system. (nih.gov)
  • scientists
  • In a new video, NIH scientists provide an overview of chronic granulomatous disease (CGD), describe its symptoms and prevalence, and discuss how treatments for the condition have advanced. (nih.gov)
  • food allergy
  • In a person with food allergy, the immune system reacts abnormally to a component of a food-sometimes producing a life-threatening response. (nih.gov)
  • Food allergy negatively influences the quality of life of patients and their families and is potentially life-threatening to those affected. (nih.gov)
  • Read more about NIAID's commitment to food allergy research. (nih.gov)
  • If you have a food allergy and need practical ways to avoid packaged products that contain food allergens , the Food and Drug Administration offers information. (nih.gov)
  • Personal medical history, family history, age and other factors can influence the likelihood that a person develops food allergy. (nih.gov)
  • There is presently no cure for food allergy, but some experimental immunotherapies may decrease symptoms in some people with food allergy. (nih.gov)
  • The relationship between these related problems and food allergy is complex, however, and each condition requires careful monitoring. (nih.gov)
  • contagious
  • Smallpox, caused by the variola virus, was a highly contagious infectious disease that caused infected individuals to develop a fever and a progressive, disfiguring skin rash. (nih.gov)
  • autoimmune diseases
  • Some of the more common autoimmune diseases include type 1 diabetes, rheumatoid arthritis, systemic lupus erythematosus, and inflammatory bowel disease. (nih.gov)
  • Treatments are available for many autoimmune diseases, but cures have yet to be discovered. (nih.gov)
  • Many autoimmune diseases disproportionately affect women, such as rheumatoid arthritis, multiple sclerosis, and systemic lupus erythematosus. (nih.gov)
  • The ACEs conduct collaborative basic and clinical research on autoimmune diseases. (nih.gov)
  • Diagnosis
  • The Therapeutic Development Services program offers a collection of preclinical services to support the development of products intended for use in the cure, mitigation, diagnosis, or treatment of disease caused by a pathogen or certain toxins. (nih.gov)
  • AIDS
  • Indeed, we have come a long way since the disease now known as AIDS was first reported in 1981. (nih.gov)
  • One of NIAID's greatest success stories is that its research led to the development of numerous antiretroviral drugs to treat HIV/AIDS, turning what was once a uniformly fatal disease into a manageable chronic condition for many. (nih.gov)
  • dengue
  • Neglected tropical diseases (NTDs), such as dengue, lymphatic filariasis, trachoma, and leishmaniasis, are called "neglected," because they generally afflict the world's poor and historically have not received as much attention as other diseases. (nih.gov)
  • This species can transmit diseases such as chikungunya, dengue, and Zika. (nih.gov)
  • Dengue fever is an infectious disease carried by mosquitoes and caused by any of four related dengue viruses. (nih.gov)
  • The goal of these tests is to provide early detection of the disease, distinguish between the different viral dengue, and predict which people are at highest risk of developing the more severe forms of the disease, dengue hemorrhagic fever and dengue shock syndrome. (nih.gov)
  • Asthma
  • Asthma is a chronic lung disease characterized by episodes of airway narrowing and obstruction, causing wheezing, coughing, chest tightness and shortness of breath. (nih.gov)
  • Flu infection can present particularly serious problems for young children, the elderly, pregnant women and people with certain medical conditions, such as asthma and heart disease. (nih.gov)
  • People with DOCK8 immunodeficiency syndrome also typically have allergies, asthma, and an increased risk for some types of cancer. (nih.gov)
  • Ebola
  • The randomized, controlled trial is enrolling patients of any age with confirmed Ebola virus disease (EVD) at a treatment unit in the city of Beni operated by The Alliance for International Medical Action (ALIMA) , a medical humanitarian organization. (nih.gov)
  • Tuberculosis
  • Anthony S. Fauci, Addressing the Tuberculosis Epidemic: 21st Century Research for an Ancient Disease Journal of the American Medical Association DOI: 10.1001/jama.2018.12852. (nih.gov)
  • Development
  • Product development goals in this arena have shifted from a "one bug-one drug" approach to a more flexible strategy that is applicable to a broad spectrum of infectious diseases. (nih.gov)
  • In response to recommendations from the Tick-borne Disease Working Group, the NIH is developing a strategic plan to advance tickborne disease research and development, and is seeking comments and suggestions from stakeholders throughout the scientific research, advocacy, and clinical practice communities, and the general public. (nih.gov)
  • Smallpox
  • Vaccinia (smallpox) vaccine, derived from calf lymph, and currently licensed in the United States, is a lyophilized, live-virus preparation of infectious vaccinia virus. (nih.gov)
  • Although a worldwide immunization program eradicated smallpox disease decades ago, small quantities of smallpox virus officially still exist in two research laboratories in Atlanta, Georgia, and in Russia. (nih.gov)
  • Conditions
  • They also explain how studying CGD has not only helped people with this rare disease but also yielded insights into more common conditions. (nih.gov)
  • syndrome
  • DOCK8 immunodeficiency syndrome is a rare immune disorder named after the mutated gene responsible for the disease. (nih.gov)
  • The disease consequently was renamed DOCK8 deficiency, and later, DOCK8 immunodeficiency syndrome. (nih.gov)