• In a copper-catalyzed 1,2,3-triazole cycloaddition, an acetylene-functionalized Thermomyces lanuginosus lipase has been attached to azide-functionalized water-soluble gold nanoparticles under retention of enzymatic activity. (figshare.com)
  • Gold nanoparticles in aqueous solution exhibit an intense red colour that upon clustering of the nanoparticles changes colour to purple - readily observed with the naked eye. (ukri.org)
  • By functionalising gold nanoparticles with specific carbohydrate ligands, glyconanoparticles capable of clustering on flu virus surfaces will be developed, thus detecting and discriminating between human and animal strains. (ukri.org)
  • The thesis entitled "The Role of Liposomal Hybrids and Gold Nanoparticles in the Efficacious Transport of Nucleic Acids and Small Molecular Drugs for Cancer Nanomedicine" elucidates the preparation of various liposomal formulations of cationic monomeric and gemini lipids where hydrophobic domains were consisted of tocopherol, cholesterol and pseudoglyceryl backbone for the cellular transport of nucleic acids. (iisc.ac.in)
  • The thesis continues while elucidating the role of various pH sensitive molecules and gold nanoparticles in liposomes to improve the delivery efficacy levels. (iisc.ac.in)
  • This thesis also elucidates the role of gold nanoparticles stabilized with natural pH sensitive molecules for efficacious drug delivery applications. (iisc.ac.in)
  • Additionally, the role of such pH sensitive gold nanoparticles in association with liposomes for the co-delivery of drug and gene has been discussed. (iisc.ac.in)
  • Recently, work has explored the synthesis and exchange bias effect in these Co core CoO shell nanoparticles with a gold outer shell. (wikipedia.org)
  • I lead a mini research project in the third year undergraduate teaching laboratory focussing on the synthesis and catalytic properties of palladium nanoparticle/carbon nanotube nanocomposites. (nottingham.ac.uk)
  • Facile, reproducible, and modular chemistries were utilized for incorporating zwitterions into a range of polymer backbones, and strategies were developed for overcoming difficult challenges encountered in zwitterionic polymer synthesis, especially related to the varying solubility of zwitterions, hydrophobic polymers, and functional comonomers. (umass.edu)
  • Chemistry) Synthesis polymer-bound small-molecule kinase inhibitors as anti-tumour agents. (sun.ac.za)
  • Chapter One provides a general introduction of the research on metal oxide nanoparticles (MOx), highlighting their synthesis, surface modification, and functionalization. (unc.edu)
  • Chapter Two describes in detail the thermal degradation synthesis used for the generation of small MOx nanoparticles. (unc.edu)
  • It demonstrates the versatile of the synthesis by successfully synthesizing ZrO2 and IrO2 nanoparticles. (unc.edu)
  • Castonguay, A.* Synthesis and biological assessment of a ruthenium(II) cyclopentadienyl complex in breast cancer cells and on the development of zebrafish embryos, European Journal of Medicinal Chemistry 2020 (in press). (inrs.ca)
  • The prepared nanomaterials are zinc oxide and silver nanoparticles, reduced graphene oxide nanosheets and semiconductor quantum dots. (ru.ac.za)
  • One phthalocyanine (5b) was drop-dried on the electrode then silver nanoparticles were electrodeposited on it taking advantage of metal-N bond. (ru.ac.za)
  • The magnetic moment of ferrite nanoparticles can be greatly increased by controlled clustering of a number of individual superparamagnetic nanoparticles into superparamagnetic nanoparticle clusters, namely magnetic nanobeads. (wikipedia.org)
  • Just like non-magnetic oxide nanoparticles, the surface of ferrite nanoparticles is often modified by surfactants, silica, silicones or phosphoric acid derivatives to increase their stability in solution. (wikipedia.org)
  • Preparation of novel functional polymeric nanoparticles and various applications. (sun.ac.za)
  • Propargyl-PEG-acid has been widely used in the development of various drug delivery systems, including polymeric micelles, liposomes, and nanoparticles. (axispharm.com)
  • Abstract: Au nanoparticles supported on cerium oxide/graphitic carbon nitride (CeO2@g-C3N4) was synthesized and used as heterogeneous catalyst in redox reaction. (sharif.edu)
  • Single particle spectroscopy techniques have therefore become the standard for understanding how the energy of the localized surface plasmon of individual nanoparticles scales with small changes in the morphology. (acs.org)
  • This Perspective discusses how different single particle imaging and spectroscopy techniques together with electron microscopy can be applied to reveal the relationships between the plasmonic response and the morphology of individual nanoparticles as well as their assemblies. (acs.org)
  • Further, this method has demonstrated control over nanoparticle size and morphology, displaying a wide variety of applications for the generation of materials with excellent catalytic properties. (unc.edu)
  • The Spotahome Blog epub college practical chemistry EMG and morphology is a invalid ein because there are 6ieg downtime views which hand-make interested. (fastatmosphere.com)
  • A successful modification of titanium dioxide (TiO 2 ) nanoparticles surfaces by a grafting-to polymer technique combining catalytic chain transfer and thiol -ene click chemistry is reported. (rsc.org)
  • It is estimated that the equivalent of approximately seven fully active lipase molecules are attached to each nanoparticle. (figshare.com)
  • The surface of a maghemite or magnetite magnetic nanoparticle is relatively inert and does not usually allow strong covalent bonds with functionalization molecules. (wikipedia.org)
  • An image on the right shows the same twin cell under the action of the applied electric field: Ferroelectric nanoparticles (FNP), being aligned by an external electric field, hold liquid crystal (LC) molecules in homeotropic state even when an external electric field attempts to orient a liquid crystal in an orthogonal direction. (nanowerk.com)
  • As a result, the team was able to observe an inverse guest-host effect: ferroelectric nanoparticles reorient and hold liquid crystal molecules in a direction of the orientation of nanoparticles even when an external electric field attempts to orient a liquid crystal in an orthogonal direction as shown at the right of Figure 1. (nanowerk.com)
  • With the help of click chemistry products, scientists can attach special 'tags' to drug molecules or imaging probes. (medsnews.com)
  • Bioorthogonal chemistry empowers experts to work with molecules with exceptional precision. (medsnews.com)
  • Theoretical Chemistry involves the development of new mathematical models to describe the properties of molecules, using techniques from quantum mechanics, statistical mechanics, and chemical dynamics. (gatech.edu)
  • Propargyl-PEG-acid(Acid-PEG-Alkyne) is a chemical compound belonging to the class of polyethylene glycol (PEG) derivatives, which contains a carboxylic acid functional group (-COOH) attached to the end of a PEG chain via a propargyl linker (-C≡CH). The propargyl group is an alkyne functional group that allows for click chemistry reactions with azide-functionalized molecules. (axispharm.com)
  • Because of this one-of-a-kind quality, bioorthogonal chemistry is helpful in many fields, from biological research to biomedical applications. (medsnews.com)
  • Characterization of CNC physiochemical properties, especially its surface chemistry, is essential for the CNC-based materials development. (auburn.edu)
  • SPAAC reactions were also used to label azide-functionalized nanoparticles (SCK-NP) resulting in [64Cu]Cu-DOTA-SCK-NP with high molar activity (~36 TBq/μmol). (rankaza.com)
  • The click chemistry reaction between the propargyl group and azide-functionalized targeting ligands or drugs provides a facile method to incorporate specific functional moieties into the PEG chain, enabling the selective and efficient delivery of drugs to target sites. (axispharm.com)
  • Castonguay, A.* Anticancer Activity and Catalytic Potential of Ruthenium(II) Arene Complexes with N,O donor Ligands, Inorganic Chemistry 2018, 57, 7558. (inrs.ca)
  • The advantages compared to ferrite or elemental nanoparticles are: Higher magnetization Higher stability in acidic and basic solution as well as organic solvents Chemistry on the graphene surface via methods already known for carbon nanotubes Several methods exist for preparing magnetic nanoparticle. (wikipedia.org)
  • Nanoparticles with a magnetic core consisting either of elementary Iron or Cobalt with a nonreactive shell made of graphene have been synthesized recently. (wikipedia.org)
  • EN] A new colorimetric system for NO(g) detection is described. (upv.es)
  • The aim of this project is to develop a simple diagnostic test, based on practical and inexpensive gold nanoparticle-based colorimetric assays. (ukri.org)
  • The Journal of Physical Chemistry Letters 2019 , 10 (18) , 5372-5380. (acs.org)
  • This also implies that for the same moment, metallic nanoparticles can be made smaller than their oxide counterparts. (wikipedia.org)
  • Complex 2 alone and when conjugated to zinc oxide nanoparticles were studied for their nonlinear optical behaviour. (ru.ac.za)
  • In fact, one can use a suitable salt (such as lithium perchlorate) in the aqueous phase to achieve nanoparticle electrodeposition. (unc.edu)
  • The Journal of Physical Chemistry C 2023 , 127 (29) , 14326-14335. (acs.org)
  • The reduction in particle aggregate size and changes to the particle surface chemistry, following polymer grafting, was found to reduce cellular uptake and diminish cytotoxicity for both human lung cell lines tested. (rsc.org)
  • Luke Connal received a bachelor of Chemical Engineering and a PhD in polymer chemistry both from the University of Melbourne, Australia. (edu.au)
  • Professor Wang said: "We have successfully demonstrated that this method enables the monitoring of stepwise chemical transformations, such as glycosylation, peptide esterification, and a copper nanoparticle/cluster-catalyzed click reaction. (thieme.de)
  • Some of these MPcs (1a, 3 and 4) were directly clicked on azide grafted electrode, while some (1b, 1c, 2, 5a and 5b) were clicked to azide functionalised nanomaterials and then drop-dried on the electrodes. (ru.ac.za)
  • These problems can be solved through nanodroplet-mediated electrodeposition, a technique where water nanodroplets are filled with metal salt precursors that form stable nanoparticles when they collide with a negatively-biased electrode. (unc.edu)
  • Electrochemisty of the quasi-diffusing nanoparticles was evaluated via cyclic voltammetry (CV), chronoamperometry (CA), and mircodisk electrode (µE) experiments. (unc.edu)
  • Controlled Overgrowth of Five-Fold Concave Nanoparticles into Plasmonic Nanostars and Their Single-Particle Scattering Properties. (acs.org)
  • Uncoated particles were trapped in CF sputum pretreated with NAC nearly to the same extent as in native sputum, suggesting that NAC treatment alone offered little improvement to particle penetration.NAC facilitated rapid diffusion of PEG-coated, muco-inert nanoparticles in CF sputum. (omicsdi.org)
  • Therefore, it is usually quite a bit to ask whether using nanoparticles in a quantum-mechanical framework is also also the best way to combine a quantum-across particle. (chemistryexamhero.com)
  • This approach is a promising procedure for future cost-effective energy conversion systems relying on electrocatalytic nanoparticles. (unc.edu)
  • Nanoscience is the field of science that focuses on the study of nanoparticles , which are incredibly small particles that have a diameter of 1 to 100 nanometers. (shalom-education.com)
  • The presence of vinylic end groups was then exploited to attach the polymers to thiol functionalized TiO 2 nanoparticles via thiol -ene Michael nucleophilic reactions. (rsc.org)
  • PC- and SB-siloxane homopolymers and block copolymers were synthesized using thiol-ene 'click' chemistry, and their assembly in water and at oil-water interfaces was investigated. (umass.edu)
  • While nanoparticles are smaller than 1 micrometer in diameter (typically 1-100 nanometers), the larger microbeads are 0.5-500 micrometer in diameter. (wikipedia.org)
  • A simple and versatile method for the preparation of functional enzyme−gold nanoparticle conjugates using "click" chemistry has been developed. (figshare.com)
  • The term click chemistry has been introduced with a goal to develop an expanding set of powerful, selective, and modular blocks that work reliably in both small- and large-scale applications includes reactions that are high yielding, wide in scope, create only by-products that can be removed without chromatography, are stereospecific, simple to perform, and can be conducted in easily removable or benign solvents. (alliedacademies.org)
  • Click reactions usually join a biomolecule and a reporter molecule. (alliedacademies.org)
  • These bioorthogonal reactions find extensive applications in various fields, including radionuclide conjugate , metabolic engineering, drug target identification, medicinal chemistry, and more. (rankaza.com)
  • The answer lies in its remarkable ability to provide a 'click-and-go' approach to chemical reactions. (medsnews.com)
  • Bioorthogonal chemistry provides a collection of reactions that experts can execute selectively without causing any interference. (medsnews.com)
  • For instance, some experts have used bioorthogonal click reactions to mark proteins with fluorophores for super-resolution microscopy. (medsnews.com)
  • 41) Chen, C., Wylie R., Klinger D., Connal L. A. 'Shape control of soft nanoparticles and their assemblies' Chem. (edu.au)
  • The focus of the research activities is within some major areas of modern biochemistry, structural biology and biophysical chemistry, covering topics such as structure, function and dynamics of enzymes, membrane proteins, molecular interactions, large macromolecular assemblies. (lu.se)
  • I lead tutorials for the CHEM3003 (Bioinorganic and Metal Coordination Chemistry) and CHEM3002 (Catalysis) modules. (nottingham.ac.uk)
  • Chapter Three details the surface modification of ITO nanoparticles and subsequent electrochemical tagging with a ferrocene moiety. (unc.edu)
  • Chapter Four investigates spectroscopic tagging of ITO and ZrO2 nanoparticles as well as electrochemical tagging of ZrO2 and IrO2 nanoparticles. (unc.edu)
  • I then joined the Nottingham Nanocarbon Group in the School of Chemistry, University of Nottingham as a Research Fellow. (nottingham.ac.uk)
  • In 2017 he moved his group to the Research School of Chemistry at the Australian National University. (edu.au)
  • Chemistry is the central science, and the School of Chemistry and Biochemistry is at the heart of wide-ranging molecular research at Georgia Tech and elsewhere. (gatech.edu)
  • The School of Chemistry and Biochemistry has a strong group of faculty working in the development and application of theoretical chemistry methods. (gatech.edu)
  • Beyond 18F, radiometal ions can be conjugated to radionuclides using a click-to-chelate strategy after CuAAC. (rankaza.com)
  • Bioorganic and Medicinal Chemistry. (wustl.edu)
  • One of the most common uses of bioorthogonal chemistry is to label biomolecules like proteins, nucleic acids, and lipids in a specific way. (medsnews.com)
  • Iceni Diagnsoptics offers bespoke solutions to third parties with requirement in carbohydrate and bioconjugation chemistry. (ukri.org)
  • Lipid nanoparticles have undergone significant advancements in biomedicine, evolving into a sophisticated platform for delivering therapeutic agents and imaging agents. (ipi-singapore.org)
  • The plasmonic properties of noble-metal nanoparticles are extremely sensitive to their size and shape. (acs.org)
  • Very small and very large nanostructures each present a unique set of challenges, and a separate strategy for each kind of sample is necessary for fully revealing the relationships among size, shape, orientation, and spacing between nanoparticles. (acs.org)
  • The size of the prepared ferroelectric nanoparticles was in the range of 10-20 nm (BaTiO 3 ), 20-60 nm (Sn 2 P 2 S 6 ), 20-50 nm (CuInP 2 S 6 ) and 40-90 nm (SbSI). (nanowerk.com)
  • 10 nm) MOx nanoparticles with narrow size distributions. (unc.edu)
  • The table below compares the size of nanoparticles to coarse particles and fine particles. (shalom-education.com)
  • These nanoparticles underwent a ligand exchange with a covalently binding mondentate silane terminated with a primary amine. (unc.edu)
  • These groups collaborate closely to form a tight-knit theoretical chemistry core that is more than the sum of its parts. (gatech.edu)
  • Research topics include improved molecular dynamics and Monte Carlo simulations, efficient quantum dynamics techniques, electronic structure methods that yield a deeper understanding of intermolecular forces, and the incorporation of machine learning in theoretical chemistry. (gatech.edu)
  • Host-Guest Chemistry in Boron Nitride Nanotubes: Interactions with Polyoxometalates and Mechanism of Encapsulation JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. (nottingham.ac.uk)
  • Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers. (omicsdi.org)
  • To optimally penetrate biological hydrogels such as mucus and the tumor interstitial matrix, nanoparticles (NPs) require physicochemical properties that would typically preclude cellular uptake, resulting in inefficient drug delivery. (omicsdi.org)
  • Castonguay, A.* Cu-catalyzed click conjugation of cobalamine to a BODIPY-based fluorophore: a versatile tool to explore the cellular biology of vitamin B12 (in press). (inrs.ca)