Smad3 ProteinSmad4 ProteinSmad7 ProteinSmad1 ProteinSmad5 ProteinSmad ProteinsSmad8 ProteinOctamer Transcription Factor-3Homeodomain ProteinsEmbryonic Stem CellsSOXB1 Transcription FactorsTransforming Growth Factor betaPluripotent Stem CellsTrans-ActivatorsSignal TransductionDNA-Binding ProteinsCell DifferentiationBone Morphogenetic ProteinsGene Expression Regulation, DevelopmentalTransforming Growth Factor beta1Nuclear ReprogrammingReceptors, Transforming Growth Factor betaGerm LayersStage-Specific Embryonic AntigensCell LineActivinsTranscription FactorsCell ProliferationPromoter Regions, GeneticGrowth Differentiation Factor 3Cells, CulturedGene Expression RegulationInduced Pluripotent Stem CellsNeoplastic Stem CellsTranscription, GeneticReverse Transcriptase Polymerase Chain ReactionCell DedifferentiationProtein BindingEmbryo, MammalianHMGB ProteinsKruppel-Like Transcription FactorsLeukemia Inhibitory FactorBone Morphogenetic Protein 4Bone Morphogenetic Protein 2GATA6 Transcription FactorCell Line, TumorGene Knockdown TechniquesEndodermEmbryonal Carcinoma Stem CellsChromatin ImmunoprecipitationPhosphorylationBlastocyst Inner Cell MassCell LineageBlotting, WesternBlastocystFibroblastsStem CellsTranscriptional ActivationRNA, MessengerMolecular Sequence DataGenes, ReporterBone Morphogenetic Protein ReceptorsGene Expression ProfilingEmbryoid BodiesRNA InterferenceEmbryo Culture TechniquesBone Morphogenetic Protein Receptors, Type ITeratomaNodal ProteinCell NucleusMinkXenopus ProteinsDioxolesPseudogenesEmbryonic DevelopmentBone Morphogenetic Protein 7MesodermDown-RegulationCarcinoma, EmbryonalRNA, Small InterferingTransfectionBase SequenceLuciferasesModels, BiologicalFibrosisMice, KnockoutCOS CellsTransforming Growth Factor beta2ImmunoprecipitationEpithelial-Mesenchymal TransitionProtein Structure, TertiaryActivin ReceptorsBinding SitesImmunohistochemistryGene Expression Regulation, NeoplasticTranscription Factor 3Spheroids, CellularGene ExpressionActivin Receptors, Type IICell Culture Techniques