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  • UCLA
  • Yi Tang, a professor of chemical and biomolecular engineering and a member of the California NanoSystems Institute at the University of California-Los Angeles (UCLA), led the group that created the nanocapsules, which are about 100 nanometers in size. (oncologynurseadvisor.com)
  • As the team explained in Nanotoday as well as in a statement issued by UCLA, the nanocapsules release the protein complex apoptin to the innermost part of the tumor cell, where it accumulates. (oncologynurseadvisor.com)
  • The membranes of the nanocapsules used in the new UCLA delivery method can degrade or remain intact depending on the size of the molecular substrates with which their embedded protein must interact. (nanotech-now.com)
  • found
  • LbL nanoassembly has found industrial applications including eye lens modification, improvement of cellulose fiber for better fabric and paper, microcapsules for insulin sustained release and cancer drug nanocapsules. (wikipedia.org)
  • detect
  • HDC was able to detect micelles as a byproduct of nanocapsule preparation while in PCS the sample dilution turned micelles undetectable. (ovid.com)
  • The nanocapsules can detect Raman spectra at small concentrations (for example, 1,2-bi-(4-pyridyl) ethylene (BPE) at 10-12 M) and as concentration increases, the detection sensitivity increases logarithmically. (wikipedia.org)
  • novel
  • His current research relates mainly to bottom-up pathways towards tailor-made porous metal oxide nanocapsules (like Mo132) and their use as versatile materials of interdisciplinary character including novel supramolecular chemistry. (wikipedia.org)
  • method
  • We synthesized cobalt- (Co-) doped C 60 nanowhiskers (NWs) by applying a liquid-liquid interfacial precipitation method using a C 60 -saturated toluene solution and 2-propanol with Co nitrate hexahydrate (Co(NO 3 ) 3 ⋅6H 2 O). Heating the NWs at 873-1173 K produced carbon nanocapsules (CNCs) that encapsulated Co clusters with a hexagonal-closed-packed structure. (hindawi.com)
  • core
  • This study evaluated apoptotic cell death and cell cycle arrest induced by an MTX derivative (MTX diethyl ester [MTX(OEt) 2 ]) and MTX(OEt) 2 -loaded lipid-core nanocapsules in two MTX-resistant breast adenocarcinoma cell lines, MCF-7 and MDA-MB-231. (dovepress.com)
  • For MCF-7 cells, MTX(OEt) 2 solution and MTX(OEt) 2 -loaded lipid-core nanocapsules presented significantly higher apoptotic rates than untreated cells and cells incubated with unloaded lipid-core nanocapsules. (dovepress.com)
  • For MDA-MB-231 cells, MTX(OEt) 2 -loaded lipid-core nanocapsules were significantly more efficient in inducing apoptosis than the solution of the free drug. (dovepress.com)
  • The monodisperse nanocapsules in the range of 50-200 nm consist of a dendritic polyethylene core and a Pluronic copolymer shell. (epfl.ch)
  • drugs
  • This protects the antibodies and keeps them functional in the delivery process, which stabilizes the nanocapsule and enables it to deliver the drugs more efficiently. (medicalnewstoday.com)
  • process
  • A second result of the work was the observation that, at the same time as the nanocapsules were fabricated by the arc-discharge process, regularly aligned three-dimensional, coral-like macro-aggregates were self-assembled by the nanocapsules without any template and catalyst. (nanowerk.com)
  • especially
  • Altogether, the results led us to validate our hypothesis about the ability of the PGA and PGA-PEG nanocapsules to reach the lymphatic system, especially following subcutaneous administration. (ovid.com)
  • growth
  • Tang's team reported that in tests done on human breast cancer cell lines implanted in laboratory mice, tumor growth was significantly reduced after the nanocapsules were delivered. (oncologynurseadvisor.com)
  • significant
  • The significant accumulation of the radiolabeled nanocapsules in the lymph nodes was attained at 24 and 48 h post-injection, reaching values comprised between 70% and 187% ID/g in the popliteal lymph nodes. (ovid.com)
  • results
  • The results indicate that, following intravenous administration, both types of nanocapsules exhibit a modest accumulation in the lymph nodes (≤2.3% ID/g). (ovid.com)