• The protein is a member of the tripartite motif (TRIM) family. (fishersci.com)
  • With its colorful nature motif and super-soft fleece liner, these scuffs are sure to be a happy place for your feet. (llbean.com)
  • In this paper, we study the application of an ttMM (hidden Markov model) to the problem of representing protein sequences by a stochastic motif. (aaai.org)
  • A stochastic protein motif represents the small segments of protein sequences that have a certain function or structure. (aaai.org)
  • This HMM directly reflects the characteristics of the motif, such as a protein periodical structure or grouping. (aaai.org)
  • Beverly, MA-October 22, 2002 Business Wire - Cell Signaling Technology (CST) announced today the issuance of its U.S. Patent No. 6,441,140, directed to the production of a novel class of motif-specific, context-independent antibodies, highly useful for the identification of subclasses of protein kinase substrates. (cellsignal.com)
  • This novel method is broadly applicable to any protein kinase for which a substrate consensus motif has been identified and can also be used to produce antibodies highly reactive against acetylation, methylation and proteolytic cleavage containing motifs. (cellsignal.com)
  • Noncoding" sequences are not translated into proteins, and nucleic acids with such motifs need not deviate from the typical shape (e.g. the "B-form" DNA double helix). (wikipedia.org)
  • Short coding motifs, which appear to lack secondary structure, include those that label proteins for delivery to particular parts of a cell, or mark them for phosphorylation. (wikipedia.org)
  • The ST motif is a commonly occurring feature in proteins and polypeptides. (wikipedia.org)
  • Two websites are available for finding and examining ST motifs in proteins, Motivated Proteins: and PDBeMotif. (wikipedia.org)
  • CST uses peptide libraries as immunogens to produce antibodies reactive against short linear phosphorylated motifs present in many different proteins. (cellsignal.com)
  • In biology, a sequence motif is a nucleotide or amino-acid sequence pattern that is widespread and usually assumed to be related to biological function of the macromolecule. (wikipedia.org)
  • Within a sequence or database of sequences, researchers search and find motifs using computer-based techniques of sequence analysis, such as BLAST. (wikipedia.org)
  • The Multiple Motif Meta Analysis (M3A) method can be used to identify enriched and de-enriched DNA motifs from a collection of sequences (e.g. enhancers or promoters). (sanger.ac.uk)
  • Given a set of sequences (e.g. corresponding to enhancers), and a collection of TF binding motifs (we offer several curated sets), M3A will identify motifs which are significantly enriched or de-enriched. (sanger.ac.uk)
  • Cytosine rich DNA sequences can fold into a structure called an i-motif. (news-medical.net)
  • The structure of i-motif was found using NMR, where it was found that the length of cytosine sequences ranged from 3 to 12 bases, and it may also have thymine residues in between the cytosine sequences. (news-medical.net)
  • Outside of gene exons, there exist regulatory sequence motifs and motifs within the "junk", such as satellite DNA. (wikipedia.org)
  • In occurs through the inhibition of DNA binding of cognate cis- hematopoiesis there exist several lineage branch points with regulatory motif while in the other case DNA binding is unaffected identified key transcription factors and external signals [3-5]. (lu.se)
  • Two well conserved threonines at α-helical N-termini occur as ST motifs and form part of the characteristic nucleotide binding sites of SF1 and SF2 type DNA and RNA helicases. (wikipedia.org)
  • The name 'i-motif' was chosed as it is the only nucleic acid structure with intercalated base pairs. (news-medical.net)
  • For this reason, two or more patterns are often associated with a single motif: the defining pattern, and various typical patterns. (wikipedia.org)
  • Usually, however, the first letter is I, and both [RK] choices resolve to R. Since the last choice is so wide, the pattern IQxxxRGxxxR is sometimes equated with the IQ motif itself, but a more accurate description would be a consensus sequence for the IQ motif. (wikipedia.org)
  • Structural studies of polypeptides indicate that such tetrapeptides can adopt the hydrogen bonding pattern of the ST motif. (wikipedia.org)
  • Lymphocyte activation gene 3 (LAG3) is an inhibitory immune checkpoint receptor that restrains autoimmune and antitumor responses, but its evolutionarily conserved cytoplasmic tail lacks classical inhibitory motifs. (bvsalud.org)
  • They are able to recognize motifs through contact with the double helix's major or minor groove. (wikipedia.org)
  • As with ST turns, a significant proportion of ST motifs occur at the N-terminus of an alpha helix with the serine or threonine as the N cap residue. (wikipedia.org)
  • The intercalation in i-motifs can occur in different ways leading to formation of two form;s R- and S-forms. (news-medical.net)
  • For example, an N-glycosylation site motif can be defined as Asn, followed by anything but Pro, followed by either Ser or Thr, followed by anything but Pro residue. (wikipedia.org)
  • When one of the hydrogen bonds is between the main chain oxygen of residue i and the side chain NH of residue i + 3 the motif incorporates a beta turn. (wikipedia.org)
  • A related motif is the asx motif which has aspartate or asparagine as the first residue. (wikipedia.org)
  • In particular, the 5'-G-A-3'/3'-A-G-5' motif and three of its sequence variants have a relatively high occurrence in 16S and 23S ribosomal RNA. (aaai.org)
  • Similarly, C-rich regions can fold in to a structure called i-motif or i-tetraplex or i-DNA. (news-medical.net)
  • In Origami Jewelry Motifs , you'll learn to fold more than 30 charming origami models, from animals and flowers to shapes and figures. (dickblick.com)
  • Embodying the variety and complexity of traditional Indian design, the motifs in this collection will be of immediate use to artists and illustrators as well as providing an exciting glimpse into the rich store of Indian decorative art. (doverpublications.com)
  • This made it possible for pictorial motifs to travel, spread, and transform along the way. (smb.museum)
  • Made from premium silk, this repeat-print elephant motif adds a dash of personality to formal tailoring. (thomaspink.com)
  • The presence of six or less C bases lead to intermolecular folding of i-motifs, whereas longer than six C residues promote the formation of intramolecular folding of i-motifs. (news-medical.net)
  • Reprint of 5000 Indian Designs and Motifs, originally published by The Indian Institute of Art in Industry, Calcutta, 1958. (doverpublications.com)
  • This article is a review of the book The Japanese Psyche - Major Motifs in the Fairy Tales of Japan , written by Hayao Kawai. (bvsalud.org)
  • Help support Wordnik (and make this page ad-free) by adopting the word motif . (wordnik.com)
  • When potential clients visit your office, you can make an impression with the Serta Commercial Motif High-Back Executive Chair. (officedepot.com)
  • On the occasion of the 150th anniversary, we will show you the essence of our mission for greater mobility: Embark on a journey through the eventful history of the company since its founding in 1871 with fascinating motifs and experience the development of Continental into an international technology company. (continental.com)
  • Nevertheless, motifs need not be associated with a distinctive secondary structure. (wikipedia.org)
  • An artist's impression of the i-motif DNA structure inside cells, along with the antibody-based tool used to detect it. (news-medical.net)
  • The i-motif is a tetrameric or four stranded structure consisting of two parallel duplexes (double strands) with the sequence d(TCCCCC). (news-medical.net)
  • Class representing approximate score distribution for a given motif. (biopython.org)
  • Mix-and-match the jewelry-sized motifs with headbands, necklaces, rings, and more to create your own custom j. (dickblick.com)
  • The artist Annelise Josefsen won the competition to design the anniversary motif. (norges-bank.no)
  • Following input from the Sami Parliament and the Sami Artists' Union, Norges Bank invited seven artists to participate in a competition to design the anniversary motif on the reverse of the coin. (norges-bank.no)
  • Another advancement in Air Max design, the Kids' Toddler Nike Air Max Motif Casual Shoes pay homage to the iconic Air Max 1. (finishline.com)
  • The Motif Polo's playful equestrian print allows you to show off your love of horses while riding your best, supported by the fabric's technical features. (ariat.com)
  • Using this method, we obtained an ttMM for a leucine zipper motif. (aaai.org)
  • The intricate and lush style of the Indian Motif Plantable Menu Card will be a nice touch to the tablescape and decor of your wedding festivities. (botanicalpaperworks.com)
  • Unlike many other methods, M3A relies on an annotated list of motifs which makes it easier to interpret results biologically. (sanger.ac.uk)
  • Studies have investigated the relative presence of tetraplex structures (i-motifs and G-quadraplex) and Watson-Crick duplexes. (news-medical.net)
  • In this system, the endonuclease Cas9 generates double strand breaks in DNA upon RNA-guided recognition of a complementary DNA sequence, which strictly requires the presence of a protospacer adjacent motif (PAM) next to the target site. (nih.gov)
  • The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. (fishersci.com)
  • The following table presents links to in-depth analysis for ETFs tracking the Motif New Age Consumer Index. (etfdb.com)
  • Provides a number of methods for calculating thresholds for motif occurrences. (biopython.org)