DoxorubicinChemotherapyPregnant while receiving daAllergic to dactinomycinActinomycinAntibioticPregnancyMedicationHarmPowderLiverDoseCancerSide effectsOrdered by your doctorTreat certain typesBreast-feedReceiveSpecificCombinationDoctorMedicalWorkDoxorubicinVincristine and dactinomycinCosmegenTopotecanInjectionHepaticAcuteWilmsGenericMedicationsDiseaseDrugsAgentsSideChildrenAreaRisk
Doxorubicin1
- Patients with stage III or IV disease received regimen M (vincristine, dactinomycin, and doxorubicin, alternating with 4 cycles of cyclophosphamide [Cytoxan]/etoposide [Toposar], plus radiotherapy). (ahdbonline.com)
Chemotherapy4
- Dactinomycin, also known as actinomycin D, is a chemotherapy medication used to treat a number of types of cancer. (wikipedia.org)
- Dactinomycin injection must be given in a hospital or medical facility under the supervision of a doctor who is experienced in giving chemotherapy medications for cancer. (medlineplus.gov)
- Dactinomycin is a type of antibiotic that is only used in cancer chemotherapy. (medlineplus.gov)
- It is important to realize that patients with high risk molar pregnancy receive treatment with combination chemotherapy consisting of methotrexate, dactinomycin and chlorambucil. (nethealthbook.com)
Pregnant while receiving da1
- If you become pregnant while receiving dactinomycin, call your doctor. (medlineplus.gov)
Allergic to dactinomycin1
- tell your doctor and pharmacist if you are allergic to dactinomycin, any other medications, or any of the ingredients in dactinomycin injection. (medlineplus.gov)
Actinomycin1
- The researchers applied a wide array of DNA-specific drugs, including actinomycin D, also known as dactinomycin, to pea tissue. (frontiersin.org)
Antibiotic1
- Dactinomycin is in the cytotoxic antibiotic family of medications. (wikipedia.org)
Pregnancy2
- If you are able to get pregnant, a pregnancy test will be done to show that you are NOT pregnant before starting dactinomycin. (medicine.com)
- Use birth control that you can trust to prevent pregnancy while taking dactinomycin and for 6 months after stopping dactinomycin. (medicine.com)
Medication1
- Dactinomycin often causes nausea and vomiting, but it is important to keep using this medication even if you feel ill. (medbroadcast.com)
Harm1
- Dactinomycin may harm the fetus. (medlineplus.gov)
Powder2
- Dactinomycin comes as a powder to be mixed with liquid to be injected intravenously (into a vein) by a doctor or nurse in a medical facility. (medlineplus.gov)
- Each vial contains lyophilized, amorphous yellow dactinomycin powder 500 µg and mannitol 20 mg. (medbroadcast.com)
Liver2
- Very bad blood vessel problems in the liver have happened with dactinomycin. (medicine.com)
- Amifostine appears to act protectively to liver changes caused by dactinomycin. (viamedica.pl)
Dose4
- Do not breast-feed while you take dactinomycin and for 2 weeks after your last dose. (medicine.com)
- If you are a man and your sex partner gets pregnant while you take dactinomycin or within 3 months after your last dose, call your doctor right away. (medicine.com)
- If you get pregnant while taking dactinomycin or within 6 months after your last dose, call your doctor right away. (medicine.com)
- The recommended dose and dosing schedule of dactinomycin varies according to the specific type of cancer being treated, the response to therapy, and the other medications or treatments being used. (medbroadcast.com)
Cancer6
- Dactinomycin is used in combination with other medications, surgery, and/or radiation therapy to treat Wilms' tumor (a type of kidney cancer that occurs in children) and rhabdomyosarcoma (cancer that forms in muscles) in children. (medlineplus.gov)
- Dactinomycin is also used in combination with other medications to treat certain types of testicular cancer and Ewing's sarcoma (a type of cancer in bones or muscles). (medlineplus.gov)
- Dactinomycin is also sometimes used to treat a type of cancer of the ovaries (a cancer that begins in the female reproductive organs where eggs are formed). (medlineplus.gov)
- Dactinomycin is used to treat cancer. (medicine.com)
- Dactinomycin causes the death of cancer cells by interfering with their growth and reproduction. (medbroadcast.com)
- As well as interfering with the genetic material DNA of cancer cells, dactinomycin can interfere with some of your normal cells. (medbroadcast.com)
Side effects3
- Dactinomycin may cause side effects. (medlineplus.gov)
- Worse side effects from radiation treatment have happened with dactinomycin. (medicine.com)
- What are the side effects of dactinomycin that I need to call my doctor about immediately? (medicine.com)
Ordered by your doctor1
- Use dactinomycin as ordered by your doctor. (medicine.com)
Treat certain types1
- Dactinomycin may also be used to treat certain types of cancerous tumors that are located in a specific area of the body. (medlineplus.gov)
Breast-feed1
- You should not become pregnant or breast-feed while you are receiving dactinomycin. (medlineplus.gov)
Receive1
- Your doctor will probably not want you to receive dactinomycin injection. (medlineplus.gov)
Specific1
- Dactinomycin may also be injected by a doctor directly into a specific the part of the body or the organ to treat the area where a tumor is located. (medlineplus.gov)
Combination1
- Dactinomycin is also used alone or in combination with other medications to treat gestational trophoblastic tumors (a type of tumor that forms inside a woman's uterus while she is pregnant). (medlineplus.gov)
Doctor1
- Talk to your doctor about the risks of receiving dactinomycin injection. (medlineplus.gov)
Medical1
- Dactinomycin was approved for medical use in the United States in 1964. (wikipedia.org)
Work1
- Use of some vaccines with dactinomycin may either raise the chance of an infection or make the vaccine not work as well. (medicine.com)
Doxorubicin1
- Although most secondary malignant neoplasms reported (eg, bone tumors, breast and thyroid cancers) have occurred in irradiated areas, certain chemotherapeutic agents, including doxorubicin, dactinomycin, and vincristine, may contribute to an increased risk for secondary malignancies. (medscape.com)
Vincristine and dactinomycin1
- Reports have documented hepatic toxicity with the combination of vincristine and dactinomycin even in the absence of radiation therapy (which many early reports suggested was the major etiologic factor in liver damage). (medscape.com)
Cosmegen1
- Dactinomycin is available as a solution or lyophilized powder for injection in vials of varying concentrations under the commercial name Cosmegen and must be given by the intravenous route, avoiding tissue extravasation. (nih.gov)
Topotecan1
- Coronary heart disease textbook of pediatric dcm usually entails combinations of dactinomycin, vincristine, and topotecan. (elastizell.com)
Injection3
- tell your doctor and pharmacist if you are allergic to dactinomycin, any other medications, or any of the ingredients in dactinomycin injection. (medlineplus.gov)
- Your doctor will probably not want you to receive dactinomycin injection. (medlineplus.gov)
- Talk to your doctor about the risks of receiving dactinomycin injection. (medlineplus.gov)
Hepatic1
- In large studies, between 1% and 5% of children with cancer treated with regimens including dactinomycin developed acute hepatic injury and thrombocytopenia suggestive of HTS. (nih.gov)
Acute2
- 1. Dactinomycin in acute myeloid leukemia with NPM1 mutations. (nih.gov)
- 5. Dactinomycin in NPM1-Mutated Acute Myeloid Leukemia. (nih.gov)
Wilms2
- Dactinomycin is used in combination with other medications, surgery, and/or radiation therapy to treat Wilms' tumor (a type of kidney cancer that occurs in children) and rhabdomyosarcoma (cancer that forms in muscles) in children. (medlineplus.gov)
- Dactinomycin was formally approved for use in the United States in 1964 and continues to be a valuable agent in the therapy of solid tumors of childhood (Wilms tumor, rhabdomyosarcoma) and in choriocarcinoma in adult women. (nih.gov)
Generic1
- Different insurance companies currently manufacture generic dactinomycin products, including merck & co., teva pharmaceuticals, and mylan laboratories. (sbolot.org)
Medications2
- Dactinomycin is also used in combination with other medications to treat certain types of testicular cancer and Ewing's sarcoma (a type of cancer in bones or muscles). (medlineplus.gov)
- Dactinomycin is also used alone or in combination with other medications to treat gestational trophoblastic tumors (a type of tumor that forms inside a woman's uterus while she is pregnant). (medlineplus.gov)
Disease1
- The fact that patients who received less dactinomycin than others (ie, those with relatively low-stage disease) had a low incidence of 2.8% suggests a dose-related toxicity for dactinomycin. (medscape.com)
Drugs1
- USES: Dactinomycin is used alone or with other anti- cancer drugs to treat cancer . (oceanpharmaglobal.com)
Agents1
- In many instances, it is difficult to attribute the liver test abnormalities to dactinomycin, because of the exposure to other potentially hepatotoxic agents. (nih.gov)
Side1
- Dactinomycin may cause side effects. (medlineplus.gov)
Children1
- The syndrome is more common in younger children and with higher doses of dactinomycin. (nih.gov)
Area1
- Dactinomycin may also be injected by a doctor directly into a specific the part of the body or the organ to treat the area where a tumor is located. (medlineplus.gov)
Risk1
- Dactinomycin may increase the risk that you will develop other cancers. (medlineplus.gov)