• Other names in common use include UDP galactose-N-acylsphingosine galactosyltransferase, and uridine diphosphogalactose-acylsphingosine galactosyltransferase. (wikipedia.org)
  • We discovered a potent and selective small molecule inhibitor (S202) of ceramide galactosyltransferase (CGT), the key enzyme for GalCer biosynthesis, and characterized its use as substrate reduction therapy (SRT). (nih.gov)
  • In enzymology, a N-acylsphingosine galactosyltransferase (EC 2.4.1.47) is an enzyme that catalyzes the chemical reaction UDP-galactose + N-acylsphingosine ⇌ {\displaystyle \rightleftharpoons } UDP + D-galactosylceramide Thus, the two substrates of this enzyme are UDP-galactose and N-acylsphingosine, whereas its two products are UDP and D-galactosylceramide. (wikipedia.org)
  • The systematic name of this enzyme class is UDP-galactose:N-acylsphingosine D-galactosyltransferase. (wikipedia.org)
  • An enzyme that catalyzes the conversion of UDP-galactose and N-acylsphingosine to D-galactosylceramide and UDP . (nih.gov)