Loading...
  • synthetase
  • NTHI strain 2019 with mutations in the genes encoding CMP- N -acetylneuraminic acid synthetase ( siaB ), one of the three NTHI sialyltransferases ( siaA ), and the undecaprenyl-phosphate α- N -acetylglucosaminyltransferase homolog ( wecA ) produced significantly smaller amounts of biofilm. (asm.org)
  • NeuAc
  • The most abundant sialic acid, NeuAc, is synthesized in vivo from N-acetylated D-mannosamine (ManNAc) or D-glucosamine (GlcNAc). (hmdb.ca)
  • 2019
  • Our data indicate that NTHI strain 2019 produces a biofilm containing α2,6-linked sialic acid and that the sialic acid content of the lipooligosaccharides increases concomitant with the transition of organisms to a biofilm form. (asm.org)
  • binds
  • Sialic acid is indispensable for the neuritogenic activities of gangliosides constituents which are unique in that a sialic acid directly binds to the glucose of the cerebroside, they are mutually connected in tandem, and some are located in the internal parts of the sugar chain. (hmdb.ca)
  • Serum
  • Serum and urine levels of the free acid are elevated in individuals suffering from renal failure. (hmdb.ca)
  • Anaerobic growth and cytidine 5'-monophospho-N-acetylneuraminic acid act synergistically to induce high-level serum resistance in Neisseria gonorrhoeae. (asm.org)
  • cholesterol
  • Background: Sialic acid and cholesterol are present in human milk and accumulate rapidly in the brain during development. (ku.edu)
  • Doseresponse studies and those varying both sialic acid and cholesterol intake are lacking. (ku.edu)
  • After weaning, two pups from each litter were allocated to one of four diets varying in CGMP (provided approximately 0, 20, 40 and 80 mg sialic acid/kg d-1) and the same cholesterol concentration as their dams. (ku.edu)
  • Conclusions: Increased sialic acid and cholesterol consumption during the first 4 weeks of postnatal brain growth influenced brain composition in rats. (ku.edu)
  • role
  • We speculate that the increased sialic acids may underlie the compensatory mechanism through its lipid-lowering role in regulating RCT in patients with CVD. (biomedcentral.com)