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  • proteins
  • Organization of the genetic locus for chicken myosin light chain kinase is complex: multiple proteins are encoded and exhibit differential expression and localization. (springer.com)
  • In certain cells, activation of FP also stimulates G12/G13-Gβγ G proteins to activate the Rho family of GTPases signaling proteins and Gi-Gβγ G proteins to activateRaf/MEK/mitogen-activated kinase pathways. (wikipedia.org)
  • Naa10, as part of the NatA complex, is bound to the ribosome and co-translationally acetylates proteins starting with small side chains such as Ser, Ala, Thr, Gly, Val and Cys, after the initiator methionine (iMet) has been cleaved by methionine aminopeptidases (MetAP). (wikipedia.org)
  • Once bound to Ca2+, calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins such as kinases or phosphatases. (wikipedia.org)
  • When calcium is present, CaM undergoes a conformational change, and the hinge region is able to bind helical peptide chains on target proteins, such as M13. (wikipedia.org)
  • sequence
  • The regulatory site consists of the CaM-binding sequence and the pseudosubstrate sequence, which inhibits the kinase activity in the absence of Ca 2+ /CaM by binding to the active site of the kinase domain (2 for review). (springer.com)
  • Isoforms
  • The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. (wikipedia.org)
  • RLC and the second ventricular light chain, essential light chain (ELC, MYL3), are non-covalently bound to IQXXXRGXXXR motifs in the 9 nm S1-S2 lever arm of the myosin head, both alpha (MYH6) and beta (MYH7) isoforms. (wikipedia.org)