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  • satellite cells
  • Mammalian skeletal muscle can remodel, repair, and regenerate itself by mobilizing satellite cells, a resident population of myogenic progenitor cells. (pnas.org)
  • In line with compromised myogenic potential of aged muscle-derived satellite cells, there were age-related alterations in mitochondrial biogenesis and autophagy pathways, with satellite cells derived from TRI being more susceptible to impairments with age. (ufl.edu)
  • Also, aged satellite cells lose their ability to upregulate the factors involved in the early phases of myogenic differentiation (e.g. (thefreelibrary.com)
  • Thus, the increasing evidence indicates resetting of the regulatory systems that lead to altered phenotype of satellite cells in aged muscles. (thefreelibrary.com)
  • contrast
  • In contrast, all four myogenic regulators induced expression of the cell cycle regulators p21, Rb, and cyclin D3 and promoted cell cycle arrest independently of the SWI/SNF enzymes. (umassmed.edu)
  • retinoic acid
  • A clonal line derived from retinoic acid-treated P19s (9E11G) stably expressed multiple characteristics of differentiated smooth muscle, including smooth muscle-specific isoforms of α-actin and myosin heavy chain, as well as functional responses to the contractile agonists phenylephrine, angiotensin II, ATP, bradykinin, histamine, platelet-derived growth factor (PDGF)-AA, and PDGF-BB. (ahajournals.org)
  • Mice
  • Myogenic progenitor cells isolated from these mice were severely deficient in their ability to form myotubes as compared with myogenic progenitor cells from wild-type littermates. (pnas.org)
  • hepatocyte
  • Other markers such as DLK1/FA1, a member of the EGF-like family and c-Met, the receptor for hepatocyte growth factor showed that satellite cell heterogeneity in human muscle is far greater than previously shown. (diva-portal.org)
  • dendritic
  • Dr. Hargadon's article discusses not only the most current research on dendritic cell immunosuppression by melanoma but also other factors that influence dendritic cell function in the context of this cancer, including factors that influence the immunogenicity of tumor cell death, tumor-altered dendritic cell metabolism, and microbiome influences on dendritic cell-mediated anti-tumor immunity. (hsc.edu)
  • receptor
  • The reduction in PKB/Akt activation is accompanied by an impaired insulin-like growth factor 1 receptor (IGF-1R) activation. (rupress.org)
  • mitochondria
  • We examined the effects of exercise on skeletal muscle mitochondria in older (age = 67.3 +/- 0.6 years) men (n = 5) and women (n = 3). (biomedsearch.com)
  • To further understand the underlying cause for the age-associated decrement of mitochondrial density and function in equine skeletal muscle, expression of factors involved in mitochondria biogenesis and mitochondria-selective autophagy pathways, two of the most prominent quality control mechanisms that have been described, were analyzed. (ufl.edu)
  • prevalence
  • Black water also has a low concentration of minerals and a marked absence of calcium and magnesium ions [ 4 ] and has been characterized as having a dearth of nutrients, low penetration of sunlight, lack of aquatic plants [ 5 , 6 ], and prevalence of fish species that are small in size, which means a miniaturization process of different fish species found in this water system. (hindawi.com)
  • investigate
  • We retrospectively analyzed the results of CT-guided lung biopsies for 325 cases to investigate physical risk factors for pneumothorax development. (readbyqxmd.com)
  • suggests
  • Moreover, the increment of the glial-derived neurotrophic factor and neurotrophin 4 observed in the grafted muscles suggests that this partial neuroprotective effect is mediated by neurotrophic factor release at the neuromuscular junction level. (biomedcentral.com)
  • population
  • We thus identified potential molecular mediators of the inhibitory effects of SOD1 G93A on myogenic program and disclosed potential signaling, activated by SOD1 G93A , that affect the identity of the myogenic cell population. (hindawi.com)
  • role
  • Clearly, there are factors other than myosin that play a role in defining the characteristics of a fiber, and some of these other factors are discussed. (ovid.com)
  • group
  • In the 20RM (maximal weight with 20 reps) bench press tests both the 3- and 5-SETS groups saw significantly greater strength increases than the 1- SET group, with the 5-SETS protocol also producing significantly greater increases in strength, than the 3-SETS group (p≤0.05). (blogspot.com)
  • Methods: Forty healthy adult SD rats were randomly divided into 5 groups: blank control group (BC), spontaneous breathing group (SB), electrical stimulation group (ES), mechanical ventilation group (MV), and electrical stimulation and mechanical ventilation group (MS). The rats in each group were treated for 18 h except for the BC group. (readbyqxmd.com)
  • function
  • Neuromuscular Electrical Stimulation Combined with Protein Ingestion Preserves Thigh Muscle Mass But Not Muscle Function in Healthy Older Adults During 5 Days of Bed Rest. (nih.gov)
  • significant
  • All training groups recorded significant strength gains for bench press (BP), front lat pull down (LPD), shoulder press (SP) and leg press (LP) (p≤0.05) exercises, but the 5RM (maximal weight the subjects could lift 5 times) increased significantly more for both bench presses and lat pulldowns in the 5- SETS compared to the other training groups (p ≤ 0.05). (blogspot.com)
  • Exercise
  • Modifying Set Numbers: 1, 3, or 5 Sets - How Many Shall We do per Exercise in 2015? (blogspot.com)
  • The training resistance was increased by 5-10% for the next session when subjects were able to perform more than 12 repetitions in all sets of an exercise. (blogspot.com)