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  • mainly
  • All patients exhibited quasicontinuous rhythmic myoclonus mainly involving hands and face, accompanied by rhythmic 5- to 10-Hz electroencephalographic (EEG) activity. (docme.ru)
  • patients
  • We used voxel-based morphometry and spatially unbiased infra-tentorial template analyses of structural magnetic resonance imaging (MRI) scans, and functional MRI (fMRI) scans during block and event-related go/no-go motor tasks to study 13 EPM1 patients with mild to moderate myoclonus. (springer.com)
  • seizures
  • If myoclonus is severe, the same drugs used to prevent seizures (anticonvulsants), such as clonazepam or valproate, are sometimes helpful. (health-cares.net)
  • Onsets of central nervous system signs, such as myoclonus, tremors, muscular twitching, agitation, and tonic-clonic seizures, have been reported in humans and laboratory animals treated with chlorambucil. (vetcontact.com)
  • clonazepam
  • Sodium valproate is an alternative therapy for myoclonus and can be used either alone or in combination with clonazepam. (medic8.com)
  • Although clonazepam and sodium valproate are effective in the majority of people with myoclonus, some people have adverse reactions to these drugs. (medic8.com)
  • Valproic acid and clonazepam are effective for treating symptomatic myoclonus in many individuals. (health-cares.net)
  • Clonazepam is a commonly issued drug for sleep myoclonus, and when taken near bedtime has the added benefit of causing drowsiness. (sleepassociation.org)
  • Sodium valproate can be used separately or in conjunction with clonazepam to treat myoclonus as well. (sleepassociation.org)
  • diagnosis
  • Also, children with only occasional or subtle opsoclonus or myoclonus are harder to recognize and may carry the wrong diagnosis for years. (rarediseases.org)
  • Myoclonus describes a symptom and generally is not a diagnosis of a disease. (smartdraw.com)
  • The diagnostic work-up in myoclonus is often time-consuming and costly, and a definitive diagnosis is reached in only a minority of patients. (ovid.com)
  • indicate
  • The polysomnogram will not only detect any other possible sleeping disorders, but may also indicate whether the myoclonus itself is causing restless sleep. (sleepassociation.org)
  • stimulus
  • Myoclonus has been connected to several areas of the brain, and in many cases stimulus-sensitive myoclonus has been shown to be an overreaction of the brain in areas that control movement in response to startling events. (sleepassociation.org)
  • Patients
  • Data from patients with spinal myoclonus, who reported starting treatments within the last 5 years. (patientslikeme.com)
  • Objective: (1) To study the neuropsychological and psychopathological profile in myoclonus-dystonia (M-D) patients with and without a mutation in the DYT11 gene. (uva.nl)
  • In severely affected patients, deep brain stimulation of the globus pallidus internus has been used successfully to treat both dystonia and myoclonus. (biomedsearch.com)
  • [3,5,When anesthesia is induced with etomidate, 50-80% of patients who are not premedicated experience myoclonus. (asahq.org)
  • We also pretreated volunteers and patients with small doses of etomidate in an effort to suppress subcortical activity and to reduce the incidence of myoclonus. (asahq.org)
  • 3) a dose-ranging study in patients to determine what pretreatment dose affected the incidence of myoclonus. (asahq.org)