• Noninvasive assessment myocardial viability: current status and future directions. (smw.ch)
  • The coverage of nuclear cardiology is excellent, with all aspects of ventricular function, myocardial perfusion imaging, and viability assessment clearly summarized and with extensive illustrations and case examples provided. (snmjournals.org)
  • Techniques evaluating these myocardial states have included metabolic and perfusion imaging and assessment of contractile reserve. (escardio.org)
  • The clinical gold standard for the viability assessment is 2-D late gadolinium enhanced magnetic resonance imaging (LGE-MRI). (kobv.de)
  • I would consider cardiac MRI as the gold standard for the assessment of myocardial viability. (emedinexus.com)
  • We concluded that evaluation of functional parameters provides the best assessment of myocardial performance during EVHP, which highlights the need for an EVHP device capable of assessing the donor heart in a physiologic working mode. (canada.ca)
  • These imaging modalities enable the assessment of blood flow, detection of ischemic heart disease, identification of areas with reduced blood supply, and evaluation of myocardial viability after a heart attack. (afternoonheadlines.com)
  • Cardiovascular magnetic resonance (CMR) offers a comprehensive assessment of heart failure patients and is now the gold standard imaging technique to assess myocardial anatomy, regional and global function, and viability. (ox.ac.uk)
  • Furthermore, it allows assessment of perfusion and acute tissue injury (edema and necrosis), whereas in nonischemic heart failure, fibrosis, infiltration, and iron overload can be detected. (ox.ac.uk)
  • Nuclear medicine procedures are also useful in the assessment of myocardial viability in patients with left ventricular dysfunction, in the assessment of interventions for the evaluation of patients after percutaneous transluminal coronary angioplasty and coronary artery bypass grafting. (cnr.it)
  • Feasibility of integrating high-spatial-resolution 3D breath-hold coronary MR angiography with myocardial perfusion and viability examinations. (umassmed.edu)
  • Functional parameters obtained from a left ventricular conductance catheter, oxygen consumption, coronary vascular resistance, and lactate concentration were measured, and linear regression analyses were performed to identify which parameters best correlated with myocardial performance (cardiac index: mL·min⁻¹·g⁻¹). (canada.ca)
  • Because myocardial oxygen demand is determined mainly by heart rate, systolic wall tension, and contractility, narrowing of a coronary artery typically results in angina that occurs during exertion and is relieved by rest. (msdmanuals.com)
  • B. To review the clinical trials in which myocardial perfusion imaging with ultrasound enhancing agents has been utilized to detect coronary artery disease, detect myocardial viability, and predict outcome. (nwforums.com)
  • Exercise and pharmacological cardiac perfusion imaging are appropriate and useful in the diagnosis and prognosis of chronic coronary artery disease. (cnr.it)
  • MCE is an emerging technique to assess myocardial viability. (escardio.org)
  • Viability Quantification assess "hibernating myocardium" by calculation of relative regional changes between perfusion and viability in areas hypo-perfused on rest. (thecardiacsuite.com)
  • the current problem of the Journal Zizek et al1 report their findings regarding the relationship between myocardial perfusion abnormalities left ventricular lead position and ventricular tachyarrhythmias (VT/VF) in 57 patients undergoing single-photon emission computed tomography (SPECT) myocardial perfusion PPP1R46 imaging prior to cardiac resynchronization therapy (CRT). (immune-source.com)
  • Myocardial perfusion imaging with technetium-99m-labelled methoxyisobutyl isonitrile single photon emission computed tomography (99mTc-MIBI SPECT) has proven to be an important clinical procedure in assessing the severity of myocardial ischaemia. (qxmd.com)
  • Nuclear imaging techniques such as Single-Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) play a crucial role in evaluating cardiac function, myocardial perfusion, and viability. (afternoonheadlines.com)
  • Further, T2* mapping, another parametric imaging approach, can detect and quantify myocardial iron deposition, primarily to assess iron overload cardiomyopathy. (medscape.com)
  • Myocardial perfusion is an effective way to assess narrowed arteries, the effects of a past heart attack, or the viability of further procedures, such as a stent. (radnet.com)
  • With its unique ability to evaluate perfusion at the cellular level and to assess perfusion at peak exercise stress, MPI plays an important role in diagnosing cardiovascular disease, establishing prognosis, assessing the effectiveness of therapy, and evaluating viability. (snmjournals.org)
  • its radioisotope is used to assess myocardial perfusion and viability. (mhmedical.com)
  • We compared 99mTc-MIBI myocardial perfusion imaging with other heart monitoring methods in order to assess its value in the diagnosis of children with Coxsackie viral myocarditis. (qxmd.com)
  • Besides its superiority in determining mass and volumes of the heart, structural imaging of myocardial tissue has become the domain of cardiac MRI. (medscape.com)
  • Myocardial strain imaging, a reproducible measure of LV systolic function, can identify subclinical LV dysfunction and patterns that suggest specific cardiomyopathies (eg, ischemic cardiomyopathy, amyloidosis, hypertrophic cardiomyopathy, chemotherapy-induced cardiotoxicity). (medscape.com)
  • Parametric T1 and T2 mapping sequences can be used for evaluation of diffuse, interstitial myocardial fibrosis that is not detected by LGE imaging. (medscape.com)
  • Noninvasive detection of myocardial fibrosis in arrhythmogenic right ventricular cardiomyopathy using delayed-enhancement magnetic resonance imaging. (umassmed.edu)
  • For diagnosis in clinical routine, cardiac magnetic resonance imaging is used, as it provides information about morphology, blood flow, perfusion, and tissue characterization. (kobv.de)
  • Myocardial perfusion imaging (MPI) is an important imaging modality in the management of patients with cardiovascular disease. (snmjournals.org)
  • Myocardial perfusion imaging (MPI) is a valuable tool in the management of patients with cardiovascular disease. (snmjournals.org)
  • 99mTc-MIBI myocardial perfusion imaging in myocarditis. (qxmd.com)
  • Diagnosis is by symptoms, electrocardiography, and myocardial imaging. (msdmanuals.com)
  • Once transverse data has been processed, it can be instantly reoriented to the standard short axis views associated with perfusion imaging for consistency in interpreting results. (thecardiacsuite.com)
  • A. To review the quantitative and qualitative approaches to myocardial perfusion imaging with ultrasound enhancing agents. (nwforums.com)
  • C. To review the clinical trials examining how resting myocardial perfusion imaging with ultrasound enhancing agents impacts clinical outcome in Intensive Care and Emergency settings. (nwforums.com)
  • 68 Ga-Galmydar excretes from blood pool quickly, and shows stable retention within rat myocardium in vivo for extended periods, therefore, the agent shows potential to enable myocardial perfusion imaging. (wustl.edu)
  • Conclusions: Combined data obtained from radiation dosimetry studies in mice indicate that 68 Ga-Galmydar would be safe for further evaluation of dosimetry toxicity and myocardial perfusion PET imaging in humans. (wustl.edu)
  • PET and SPECT Tracers for Myocardial Perfusion Imaging. (nih.gov)
  • Evolving use of PET viability imaging. (nih.gov)
  • When the perfusion findings were compared with other parameters, it was shown that myocardial enzyme levels, ST-T segment changes and left ventricular function correlated well with the 99mTc-MIBI-established perfusion defect severity. (qxmd.com)
  • Because ECV defines the proportion of a volume of tissue that consists of extracellular matrix or space between myocytes, it is a marker of myocardial tissue remodeling. (medscape.com)
  • The results of this study suggest that the presence of myocardial uptake of 99mTc-MIBI may be a marker of myocardial inflammation and necrosis. (qxmd.com)
  • T1 and T2 mapping better characterize myocardial tissue by identifying areas of edema (T2), inflammation, and more diffuse fibrosis (T1), which may aid in diagnosing myocarditis without LGE, amyloidosis , hemochromatosis , and Fabry disease . (medscape.com)
  • Consequently, infectious diseases, such as myocarditis, may also affect myocardial perfusion by inducing local inflammation and necrosis. (qxmd.com)
  • All 46 patients with Coxsackie viral myocarditis showed a certain degree of reduced perfusion. (qxmd.com)
  • Owing to its high-spatial resolution and 3D tomography, CMR provides superior myocardial border definition and volumetric analysis, accurate determination of regional wall thickness and myocardial mass, and sensitive detection of WMA. (medscape.com)
  • If an intact cell membrane is considered to imply a live cell, then the detection of TL-201 in a given segment is indicative of tissue viability. (escardio.org)
  • Quantify myocardial perfusion, function, and viability using multiple review screens, with integrated reporting through customizable templates. (philips.hr)
  • Because overall viability and regional viability were significantly correlated both covariates were not evaluated in the same predictive multivariable model. (immune-source.com)
  • With this novel visualization, an easy distinction between endocardial, mid-myocardial, or epicardial scar is possible. (kobv.de)
  • We do know that increasing myocardial scar increases the risk of VT/VF in patients with heart failure without CRT.2 3 Did CRT really increase the burden of VT/VF beyond the baseline risk predicted by the presence of scar? (immune-source.com)
  • The study design does not directly address this question because there was not a comparable control group of patients with heart failure left bundle branch block (LBBB) and myocardial scar who did not undergo CRT implantation. (immune-source.com)
  • QPET provides cardiac function, perfusion, and Viability quantitation using gated and ungated MPI datasets: ED and ES volumes, ejection fraction, perfusion measures such as SSS/SRS/SDS and TPD, and Myocardial blood flow. (thecardiacsuite.com)
  • Persistent stunning induces myocardial hibernation and protection: flow/function and metabolic mechanisms. (smw.ch)
  • N-13-Ammonia (NH3) and F-18- fluorodeoxyglucose (FDG) were the perfusion and the metabolic markers, respectively. (elsevierpure.com)
  • Therefore, we sought to identify metabolic and functional parameters that predict myocardial performance during EVHP. (canada.ca)
  • In more detail, the analysis of the tissue viability is very important for diagnosis, procedure planning, and guidance, i.e., for implantation of a bi-ventricular pacemaker. (kobv.de)
  • Regardless the fact that no other covariate independently predicted ventricular arrhythmias suggests that there is an important relationship between viability based on SPECT and ventricular arrhythmias in patients with systolic heart failure referred for CRT even if the mechanism is not fully understood. (immune-source.com)
  • Kassab K, Al-Ogaili A, Malhotra S. Abnormal vasodilator stress electrocardiogram with normal myocardial perfusion: Clinical decision-making and review of literature. (yumaregional.org)
  • Can the surface electrocardiogram be used to predict myocardial viability? (elsevierpure.com)
  • Heart failure (see the images below) may be caused by myocardial failure but may also occur in the presence of near-normal cardiac function under conditions of high demand. (medscape.com)
  • The results obtained in this study suggest that the discrepant viability findings of DSE and Thallium 201 redistribution testing are attributable to differences in the minimum critical mass of live myocytes required for each technique to diagnose myocardial viability. (escardio.org)
  • In this sense, Thallium 201 requires less live tissue in each segment than DSE to diagnose viability. (escardio.org)
  • abstract = "Objective-To investigate whether QRS morphology on the surface ECG can be used to predict myocardial viability.Design-ECGs of 58 patients with left ventricular impairment undergoing positron emission tomography (PET) were studied. (elsevierpure.com)
  • In this study overall and regional viability were also impartial predictors of VT/VF in the 41 patients without any prior history of these arrhythmias. (immune-source.com)
  • By implicating viability in the region of the LV lead as a cause of these arrhythmias the study seems to imply that CRT increases CID 755673 the risk of VT/VF in selected patients. (immune-source.com)
  • CID 755673 Only such a study with a control group not receiving CRT would facilitate more definitive conclusions regarding whether CRT actually causes ventricular arrhythmias in heart failure patients with overall decreased viability and/or decreased viability at the LV lead implantation site. (immune-source.com)
  • Seventeen patients (37%) showed two or more areas of diminished perfusion. (qxmd.com)
  • PET Perfusion Databases created from scans of low-likelihood patients enables normal-limit based quantification of Rb-82 and N-13-ammonia perfusion PET images. (thecardiacsuite.com)
  • MPI plays a key role in diagnosing cardiovascular disease, establishing prognosis, assessing the effectiveness of therapy, and evaluating viability. (snmjournals.org)
  • Objective-To investigate whether QRS morphology on the surface ECG can be used to predict myocardial viability. (elsevierpure.com)
  • Myocardial blood flow (MBF) and flow reserve (MFR) can be calculated from dynamic studies. (thecardiacsuite.com)
  • Toward improved standardization of PET myocardial blood flow. (nih.gov)
  • In this sense, a number of diagnostic methods are used in daily clinical practice to establish myocardial viability. (escardio.org)
  • This scan guarantees an accurate quantification of the myocardium to the extent of myocardial scarring. (kobv.de)
  • An interactive stand-alone application for the automatic segmentation, quantification, and analysis of static, gated, and dynamic myocardial perfusion PET datasets. (thecardiacsuite.com)