Myocardial ischemia or myocardial infarction. Medical search. Frequent questions

contemporary approach towards diagnosing acute myocardial ischemia. (medline.ru)
It is necessary to search for new forensic medical criteria proceeding from the practical experience of forensic medical examination when it is sometimes quite difficult to establish that death occurred as the result of the acute myocardial ischemia and to make a differential diagnostics. (medline.ru)
We have researched a possibility to apply the Enzyme Multiplied Immunoassay Technique (EMIT-test) for Troponin T to diagnose death resulting from the acute myocardial ischemia in the biological laboratory of the Leningrad Regional Bureau of Forensic Medical Examination. (medline.ru)
It means that Troponin T lends itself most widely for a diagnosis uniting the advantages of the quick and slow markers with the acute myocardial ischemia. (medline.ru)
Admit patients who have symptoms or who have concomitant acute myocardial ischemia or myocardial infarction (MI). (medscape.com)

Hashmi, S & Al-Salam, S 2015, ' Acute myocardial infarction and myocardial ischemia-reperfusion injury: A comparison ', International Journal of Clinical and Experimental Pathology , vol. 8, no. 8, pp. 8786-8796. (uaeu.ac.ae)
While effective early reperfusion of the criminal coronary artery after a confirmed AMI is the typical treatment at present, collateral myocardial ischemia-reperfusion injury (MIRI) and pertinent cardioprotection are still challenging to address and have inadequately understood mechanisms. (hindawi.com)
However, while myocardial reperfusion is well established, the process itself can trigger myocardial reperfusion injury by causing further cardiomyocyte death through multiple pathophysiological mechanisms [ 3 - 5 ]. (hindawi.com)
This coupled comorbidity of pathological ischemia and therapeutic reinjury of infarcted myocardium, namely, myocardial ischemia-reperfusion injury (MIRI), is particularly refractory to treatment [ 4 , 5 ]. (hindawi.com)
Conceptual diagram of the development and unknown mechanisms of myocardial ischemia-reperfusion injury. (hindawi.com)
Heusch G: Myocardial ischaemia-reperfusion injury and cardioprotection in perspective. (spandidos-publications.com)
Meng X, Zhang L, Han B and Zhang Z: PHLDA3 inhibition protects against myocardial ischemia/reperfusion injury by alleviating oxidative stress and inflammatory response via the Akt/Nrf2 axis. (spandidos-publications.com)
Oral dosing of rats with SCN-, before acute ischemia-reperfusion injury (30 min occlusion, 24 h or 4 week recovery), significantly reduced the infarct size as a percentage of the total reperfused area (54% versus 74%), and increased the salvageable area (46% versus 26%) as determined by MRI imaging. (ku.dk)
These data indicate that elevated levels of the MPO substrate SCN-, which can be readily modulated by dietary means, can protect against acute ischemia-reperfusion injury. (ku.dk)

MI model was also associated with increase in the neutrophil polymorphs number in the infarction related myocardium as compared to the re-perfused myocardium. (aku.edu)
Myocardial infarction (MI) refers to tissue death (infarction) of the heart muscle (myocardium) caused by ischemia, the lack of oxygen delivery to myocardial tissue. (wikipedia.org)
Time course of normalized SI after MnCl 2 infusion in different areas of the myocardium (remote, infarct and left ventricular blood pool), for mice with acute (left) or chronic (right) infarction. (biomedcentral.com)
However, whether GRh2 has a protective effect on ischaemia/reperfusion (I/R) in the myocardium has yet to be elucidated. (spandidos-publications.com)
GRh2 reduced the area of myocardial infarction and the histological changes in the myocardium and improved cardiac functions. (spandidos-publications.com)
These changes in turn can lead to the development of left ventricular hypertrophy (LVH), coronary artery disease (CAD), various conduction system diseases, and systolic and diastolic dysfunction of the myocardium, complications that manifest clinically as angina or myocardial infarction, cardiac arrhythmias (especially atrial fibrillation), and congestive heart failure (CHF). (medscape.com)

metabolic acidosis, arrhythmias, myocardial ischemia or infarction, and noncardiogenic pulmonary edema, although any organ system might be involved. (cdc.gov)
Patients with myocardial contusion causing conduction abnormalities require cardiac monitoring for 24 hours because they are at risk for sudden arrhythmias during this time. (msdmanuals.com)
Signs and clinical manifestations of severe CO poisoning include tachycardia, tachypnea, hypotension, various neurologic findings including impaired memory, cognitive and sensory disturbances, metabolic acidosis, arrhythmias, myocardial ischemia or infarction, and noncardiogenic pulmonary edema, although any organ system might be involved. (cdc.gov)

AMAE often has a cardiac aetiology, for example mural thrombi after myocardial infarction (MI), atrial thrombi associated with mitral stenosis and atrial fibrillation. (rcpjournals.org)
He had a medical history of atrial fibrillation and hypertension of 10 years' duration, and had had a myocardial infarction 4 years ago with stent placement in the left anterior descending (LAD) artery. (rcpjournals.org)

In addition, the expression of NCOR2 and NFAT in myocyte were experimentally confirmed to be associated with Schisandra in the treatment of AMI, which may be responsible for the preservation effect of myocardial contractility. (frontiersin.org)

Through the network analysis, reduction of cardiac preload and myocardial contractility was shown to be the major effect of Schisandra components, which was further experimentally validated. (frontiersin.org)
Increasing myocardial contractility in pediatric patients with heart failure. (guidelinecentral.com)

People who have a non-ST elevation myocardial infarction (NSTEMI) are often managed with the blood thinner heparin, with the additional use of PCI in those at high risk. (wikipedia.org)
When there is evidence of an MI, it may be classified as an ST elevation myocardial infarction (STEMI) or Non-ST elevation myocardial infarction (NSTEMI) based on the results of an ECG. (wikipedia.org)
Among clinical emergency events, ST-segment elevation (STE) or the non-STE electrocardiogram diagnosis of acute myocardial infarction (AMI) is particularly common worldwide, with a staggering number of annual first episodes as well as recurrent ones [ 1 ]. (hindawi.com)
In this placebo-controlled, double-blind, multicentre, multinational dose-guiding study we assessed 1883 patients who had had recent ST-elevation or non-ST-elevation myocardial infarction. (nih.gov)
Only patients with ST-segment elevation myocardial infarction (STEMI) receiving successful primary percutaneous coronary intervention (pPCI) and defined Δapelin-12 with apelin-12 elevation per cent 72 hours after pPCI compared with apelin-12 level immediately prior to pPCI were enrolled. (bmj.com)
ST-elevation myocardial infarction (STEMI) following successful primary percutaneous coronary intervention (pPCI) is the leading cause of mortality and morbidity worldwide in major adverse coronary events (MACEs) due to mechanical complications, acute heart failure and cardiac shock after successful procedure. (bmj.com)
Troponin elevation in the absence of clinical evidence of ischemia should prompt a search for other causes of cardiac damage, such as myocarditis. (medscape.com)
Uncontrolled and prolonged elevation of BP can lead to a variety of changes in the myocardial structure, coronary vasculature, and conduction system of the heart. (medscape.com)

Myocardial ischemia/infarction or Prinzmetal's angina: Perform cardiac evaluation in patients with multiple cardiovascular risk factors. (nih.gov)
Unlike the other type of acute coronary syndrome, unstable angina, a myocardial infarction occurs when there is cell death, which can be estimated by measuring by a blood test for biomarkers (the cardiac protein troponin). (wikipedia.org)
BACKGROUND: Transportation noise increases the risk of ischemic heart disease (IHD), but few studies have investigated subtypes of IHD, such as myocardial infarction (MI), angina pectoris, or heart failure. (lu.se)
RESULTS: We found road traffic noise at the most exposed façade (Lden) to be associated with higher risk of IHD, myocardial infarction (MI), angina pectoris, and heart failure, with hazard ratios (HRs) (95% confidence intervals (CI)) of 1.052 (1.044-1.059), 1.041 (1.032-1.051), 1.095 (1.071-1.119), and 1.039 (1.033-1.045) per 10 dB higher 10-year mean exposure, respectively. (lu.se)
Ischemia with no obstructive coronary artery disease (INOCA) may affect up to 62% of women undergoing coronary angiography for suspected angina, with a higher prevalence in mid-life women aged 45-65 years. (eurekalert.org)

Exposure to air pollution, especially fine particulate matter, is a leading risk factor for noncommunicable diseases, in particular: ischaemia, myocardial infarction, stroke, chronic obstructive pulmonary disease and cancers. (who.int)

In this study we investigated whether Manganese (Mn 2+ ) wash-in kinetics can add new information regarding a myocardial infarct characterization in particular if it can differentiate an acute infarct from a chronic scar. (biomedcentral.com)
For both infarction types (acute and chronic) the SI kinetics showed a fast entry of the contrast agent into the blood pool followed by a slower wash-out corresponding to the recirculation phase of Mn 2+ . (biomedcentral.com)
We observed fast entry of Mn 2+ into acute infarction followed by a recirculation phase that lead to a double contrast between infarction and "remote", whereas the entry of Mn 2+ into chronic infarction was slow and SI stayed lower than in "remote" (see figure 1 ). (biomedcentral.com)
In addition to its ability to depict accurately the infarcted area at late enhancement, Mn 2+ is also able to discriminate acute versus chronic injury by the observation of double-contrast wash-in kinetics in a mouse model of ischemia reperfusion. (biomedcentral.com)

So far, only information from the wash out phase after recirculation has been used for the detection and characterization of myocardial infarct. (biomedcentral.com)

Mn 2+ -induced signal intensity (SI) kinetics were measured into three distinct areas, remote, infarction and left ventricular blood pool and compared to ex vivo TTC and Masson's trichrome. (biomedcentral.com)

However, atropine should be administered with caution in patients with suspected myocardial ischemia, as ventricular dysrhythmias can occur in this situation. (medscape.com)

For example, up to 25% of all the acute myocardial infarctions do not cause any changes in ECG and from 20 to 30% of them do not display any aching attack, especially with older people as well as those suffering from diabetes and hypertension. (medline.ru)

Rule Out Myocardial Infarction/Ischemia Using Computer Assisted Tomography (ROMICAT-I), a blinded observational study involving patients in the emergency department with suspected acute coronary syndromes, and other studies have shown that normal findings on CCTA have a very high negative predictive value for ruling out acute coronary syndromes during the index hospitalization and the occurrence of major adverse cardiovascular events over the next 2 years. (nih.gov)
Oral direct thrombin inhibition with ximelagatran and acetylsalicylic acid is more effective than acetylsalicylic acid alone in preventing major cardiovascular events during 6 months of treatment in patients who have had a recent myocardial infarction. (nih.gov)
More cardiovascular events, including myocardial ischemia and/or infarction, were observed in treatment-experienced subjects who received maraviroc. (drugs.com)
Cardiovascular disease, including atherosclerosis, myocardial infarction, heart failure and stroke, is the leading cause of morbidity and mortality in developed nations. (frontiersin.org)

In patients with ischemic heart disease who undergo revascularization based on PET viability assessment with fludeoxyglucose F-18 (F-18 FDG), those with a low myocardial perfusion reserve were at an increased risk of adverse cardiac events. (medscape.com)
As previously discussed, the keys to achieving a good outcome in patients with cardiogenic shock are rapid diagnosis, prompt supportive therapy, and expeditious coronary artery revascularization in patients with myocardial ischemia and infarction. (medscape.com)
Despite improvements in revascularization after a myocardial infarction, coronary disease remains a major contributor to global mortality. (ku.dk)

The pathophysiological nature of MIRI is the short-term disturbance of myocardial energy and metabolism caused by reflow after ischemia and hypoxia in the coronary artery and the dynamic changes in apoptosis and the prosurvival signaling pathways in response to related injury factors. (hindawi.com)
Neonatal rat cardiomyocytes were also used to evaluate the protective effect of GRh2 on hypoxia/reoxygenation (H/R)‑induced myocardial injury in vitro. (spandidos-publications.com)

The results of two previous randomized, multicenter trials suggest that CCTA may facilitate safe and earlier triage of low-risk patients and that CCTA can rule out coronary artery disease faster than stress myocardial-perfusion imaging. (nih.gov)
It worsens heart failure and increases mortality in patients with myocardial infarction, and is an independent risk factor for death. (aafp.org)
Typical symptoms of heart disease are lacking in nearly one-third of patients with acute myocardial infarction (AMI). (dissertation.com)
Methods: This project compared ECGs in 84 patients with cardiac diagnoses, 66 (78.6%) had acute myocardial infarction with abnormal 12-lead ECGs and 18 (22.6 %) were without AMI or abnormal findings on the standard 12-lead ECG. (dissertation.com)
Patients with suspected myocardial ischemia should be treated with an appropriate anti-ischemic regimen and worked up. (medscape.com)

Myocardial ischemia is a disorder that is usually caused by a critical coronary artery obstruction, which is also known as atherosclerotic coronary artery disease (CAD). (medscape.com)
MINOCA: Myocardial infarction with no obstructive coronary artery disease. (eurekalert.org)
In an important prospective study in the Canadian Journal of Cardiology , published by Elsevier, investigators report that attending a multidisciplinary dedicated women's heart center can increase the likelihood of an accurate diagnosis and significantly improve clinical and psychological outcomes of women reporting chest pain due to insufficient heart-muscle blood flow (myocardial ischemia) but not diagnosed with obstructive coronary artery disease. (eurekalert.org)
Many women with cardiac chest pain and ischemia or myocardial infarction do not have significant blockages in the arteries supplying the heart (obstructive coronary artery disease). (eurekalert.org)
Myocardial infarction with no obstructive coronary artery disease (MINOCA) accounts for 6% of myocardial infarctions and is more frequently diagnosed in women. (eurekalert.org)
A rat model of myocardial I/R injury was constructed by ligating the left anterior descending coronary artery, which was subsequently treated with GRh2. (spandidos-publications.com)
Eight years prior to his death, the victim had a myocardial infarction (heart attack) and subsequent coronary artery bypass surgery. (cdc.gov)

A blood examination on admission revealed elevated high-sensitive troponin I (52.0 ng/mL), N-terminal pro-brain natriuretic peptide (3,193 pg/mL), D-dimer (152 ng/mL) and creatinine kinase myocardial band (196.5 U/L). ECG and blood tests were repeated 1 hour after arrival. (rcpjournals.org)
The dynamic change of troponin and wave of leads V1-5 indicated acute anterior intensive myocardial infarction. (rcpjournals.org)
The EMIT-test for Troponin T - a protein of the myocardial troponin complex - is nowadays of the great diagnostic value. (medline.ru)
The diagnosis of acute myocardial infarction (MI) is aided by a variety of serum markers, which include creatine kinase (CK) and its subclasses, troponin, myoglobin, and LDH. (medscape.com)

We report such a case, where AMI is complicated with bowel obstruction and delayed perforation in a patient with acute anterior myocardial infarction. (rcpjournals.org)
Nonrheumatic mitral regurgitation may develop abruptly, such as with papillary muscle dysfunction following myocardial infarction , valve perforation in infective endocarditis, or ruptured chordae tendineae in mitral valve prolapse. (health.am)

Sun W, Wang Z, Sun M, Huang W and Wang Y and Wang Y: Aloin antagonizes stimulated ischemia/reperfusion-induced damage and inflammatory response in cardiomyocytes by activating the Nrf2/HO-1 defense pathway. (spandidos-publications.com)

In conclusion, myocardial damage in MI is mainly due to ischemic necrosis and inflammatory mechanisms while apoptosis is the main mechanism of cell death in IR in addition to limited ischemic necrosis. (aku.edu)
The urgency of the problem to diagnose the acute ischemic disease including the acute myocardial infarction is obvious to every general practitioner. (medline.ru)
As with Mobitz I block, AV nodal agents should be avoided, and an anti-ischemic regimen should be instituted if ischemia is suspected. (medscape.com)

Diagnosis The normal heart beats in a regular, coordinated way because electrical impulses generated and spread by myocytes with unique electrical properties trigger a sequence of organized myocardial. (merckmanuals.com)
Cardiac troponins T and I are widely used for the diagnosis of myocardial injury. (medscape.com)
Many women with cardiac chest pain and ischemia or heart attack have no significant blockages of their larger coronary arteries but can have narrowing or dysfunction of their small coronary vessels or spasm of their blood vessels, which may be missed at initial diagnosis. (eurekalert.org)
PRIMARY OUTCOME MEASURES: The main outcomes were composite of all-cause death, non-fatal myocardial infarction or non-fatal stroke, based on the primary diagnosis in medical records during hospitalisation. (bvsalud.org)

Because CYP 3A4 inhibition elevates the serum levels of DIHYDROERGOTAMINE, the risk for vasospasm leading to cerebral ischemia and/or ischemia of the extremities is increased. (rxlist.com)

It is a key determinant of myocardial work and metabolic requirements. (medscape.com)

ABSTRACT This study in May 2002, part of the Jordan Department of Statistics national cross- sectional, multistage employment and unemployment survey, measured the prevalence of self- reported myocardial infarction (MI) and the association with modifiable risk factors among Jordanians aged 40+ years. (who.int)

In cases of less severe ischemia, some myocytes remain viable but have depressed contractile function. (medscape.com)
We aimed to assess the effectiveness of ximelagatran and acetylsalicylic acid for prevention of death, non-fatal myocardial infarction, and severe recurrent ischaemia after a recent myocardial infarction. (nih.gov)
The primary efficacy outcome was the dose response of ximelagatran by comparison with placebo for the occurrence of all-cause death, non-fatal myocardial infarction, and severe recurrent ischaemia. (nih.gov)

Acute mesenteric ischaemia is divided into different clinical entities which are usually considered separately. (rcpjournals.org)
The clinical picture suggested that non-occlusive mesenteric ischaemia and acute mesenteric arterial thrombosis were both present in this case. (rcpjournals.org)

When mesenteric ischaemia occurs in a patient with myocardial infarction, both the occlusive and non-occlusive types may contribute to the pathophysiologic process. (rcpjournals.org)
A myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction (tissue death) to the heart muscle. (wikipedia.org)

Serious and/or life-threatening peripheral ischemia has been associated with the coadministration of DIHYDROERGOTAMINE with potent CYP 3A4 inhibitors including protease inhibitors and macrolide antibiotics. (rxlist.com)

Among the techniques of nuclear cardiology, myocardial perfusion imaging is the most widely used. (medscape.com)
The assessment of myocardial perfusion and function using PET and hybrid positron emission tomography (PET)/CT imaging is becoming more available as the cost of the technology decreases and as positron-emitting radiopharmaceuticals become more available. (medscape.com)
One potentially important physiologic parameter obtained by these newer technologies is the myocardial perfusion reserve (MPR). (medscape.com)
Currently, nuclear myocardial scans include both perfusion and gated wall motion images. (medscape.com)

Nuclear cardiology studies are used to assess myocardial blood flow, evaluate the heart's pumping function, and visualize the size and location of a myocardial infarction. (medscape.com)
Myocardial reperfusion is the restoration of coronary blood flow after a period of coronary occlusion. (aku.edu)
Four months prior to his death, the victim was hospitalized for congestive heart failure (CHF) and, at that time, had a persantine/thallium stress test which showed a moderate amount of scarring from his previous myocardial infarction and a mild amount of myocardial ischemia (reduced blood supply to the heart). (cdc.gov)

As a main hypothesis, extracellular space is largely enhanced in acute infarction due to cell membrane rupture (necrosis) and interstitial edema, whereas scar tissue is densely composed of collagen fibers that reduce the distribution volume of free Mn 2+ ions. (biomedcentral.com)
Surgical repair is indicated for rare cases of myocardial or valvular rupture. (msdmanuals.com)

Myocardial infarction (MI) denotes the death of cardiac myocytes due to extended ischemia. (aku.edu)

Worldwide morbidity and mortality from acute myocardial infarction (AMI) and related heart failure remain high. (hindawi.com)

Chest pain is one of the most common symptoms of acute myocardial infarction and is often described as a sensation of tightness, pressure, or squeezing. (wikipedia.org)

Conclusion: ST-segment deviations and reduction in T-wave amplitude are significant indicators of acute myocardial infarction in lead I ECG, the same vector used in handheld single-lead ECG devices. (dissertation.com)

Chest pain that may or may not radiate to other parts of the body is the most typical and significant symptom of myocardial infarction. (wikipedia.org)

Schisandra chinensis is a commonly used traditional Chinese medicine, which has been widely used in the treatment of acute myocardial infarction in China. (frontiersin.org)

Anatomy10

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Psychiatry and Psychology1

Phenomena and Processes29

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Acute myocardial ischemia5

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Myocardium6

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Infarct1

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