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  • Epithelial
  • We further demonstrated that CD98-dependent amino acid transport increased renal tubular epithelial cell proliferation by a mechanism that does not require the CD98hc cytoplasmic tail. (jove.com)
  • A phenotypic measure commonly used to determine the degree of lactogenic differentiation in mouse mammary epithelial cell cultures is the formation of dome shaped cell structures referred to as mammospheres 1 . (jove.com)
  • cell
  • PDGF-AB had a moderate effect on cell proliferation (less than twofold) and PDGF-AA had no effect. (rupress.org)
  • Importantly, transcription factors and chromatin modifiers are also able to alter the cellular expression program to maintain cell identity even upon removal of the initiating differentiation stimuli [ 1 ]. (hindawi.com)
  • Differentiation processes are achieved by sculpting cell-specific epigenomes, which establish and maintain cellular diversity [ 2 ]. (hindawi.com)
  • Heterogeneity of stem cell population hampers detailed understanding of stem cell biology, such as their differentiation propensity toward different lineages. (jove.com)
  • Here, we report a method for using the micropoint laser (Andor Technology) for skeletal muscle cell injury in the zebrafish embryo. (jove.com)
  • Utilizing overexpression studies of CD98hc mutants that either lacked a cytoplasmic tail or were unable to bind to Lats we showed that CD98 increases serum-dependent cell proliferation by a mechanism that requires the CD98hc cytoplasmic tail. (jove.com)
  • Although increased amino transport markedly activated mTor signaling, this pathway did not alter cell proliferation. (jove.com)
  • While the stem cell compartment appears unaffected, interfollicular keratinocytes lacking functional Miz1 exhibit a reduced proliferation and an accelerated differentiation of the epidermis in response to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). (jove.com)
  • This decrease of oxygen tension can be due to a reduced supply in oxygen (causes include insufficient blood vessel network, defective blood vessel, and anemia) or to an increased consumption of oxygen relative to the supply (caused by a sudden higher cell proliferation rate). (jove.com)
  • regulate
  • Interestingly, the expression of microRNA 1 (miR-1), miR-27b, and miR-206, three microRNAs that have been shown to regulate SC proliferation and differentiation, is increased by a constitutively active mutant of Gαi2 [Gαi2(Q205L)] and counterregulated by Gαi2 knockdown. (asm.org)
  • regulates
  • regulates glucocorticoid- and sepsis-induced FOXO1 activation and muscle wasting. (jove.com)
  • regulates FOXO1 activation in glucocorticoid- and sepsis-induced muscle wasting and that treatment with a PPAR? (jove.com)
  • fibers
  • Equine skeletal muscle aging was accompanied by a shift in fiber type composition towards a higher percentage of type I and IIA muscle fibers, decrease in mitochondrial density and cytochrome c oxidase activity, but preserved mitochodnrial respiratory function. (ufl.edu)