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  • myocytes
  • When the number of apoptotic cardiac myocytes were counted, we found that the number was significantly decreased in AC5KO. (nii.ac.jp)
  • In H9C2 and primary rat cardiac myocytes, oligomycin treatment significantly upregulated the mRNA and protein level of NCAM in a p38-dependent manner, whereas phenylephrine and AT-II did not. (ahajournals.org)
  • Immunohistochemical analysis demonstrated that NCAM was strongly expressed in residual cardiac myocytes inside and adjacent to infarcted scars at both the acute and chronic phase, whereas it was detectable only at the intercalated discs in the non-infarcted area and sham-operated model. (ahajournals.org)
  • However, stimulation of NCAM with synthetic peptide activated AKT and increased the survival rates of cardiac myocytes dose dependently, but this effect was abolished by treatment with PI3K inhibitor. (ahajournals.org)
  • They say that "Recent evidence suggests that adult-derived stem cells, like their embryonic counterparts, are pluripotent", and that "These results demonstrate that adult liver-derived stem cells respond to the tissue microenvironment of the adult heart in vivo and differentiate into mature cardiac myocytes. (stemcellresearch.org)
  • Although fibroblast-to-myocyte electrical coupling is experimentally suggested, electrophysiology of cardiac fibroblasts is not as well established as contractile cardiac myocytes. (jove.com)
  • Here we describe and validate a protocol to isolate viable myocytes from small surgical samples of ventricular myocardium from patients undergoing cardiac surgery operations. (jove.com)
  • Evidence that human cardiac myocytes divide after myocardial infarction," The New England Journal of Medicine , vol. 344, no. 23, pp. 1750-1757, 2001. (hindawi.com)
  • alterations
  • In human heart failure, there are characteristic alterations in the cardiac β-adrenoceptor system: selective downregulation of β 1 -adrenoceptors with little or no change in β 2 -adrenoceptors, reduced adenylyl cyclase activity, increased G protein-coupled receptor kinases (GRKs) activity, and reduced neuronal noradrenaline transporter. (ahajournals.org)
  • The protocol reported here can be useful for future investigations of the cellular and molecular basis of functional alterations of the human heart in the presence of different cardiac diseases. (jove.com)
  • bone
  • 16968778 ). Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression (By similarity). (uniprot.org)
  • cellular
  • Cardiac injury increases cellular turnover in the heart, hence we subjected Kit+/MCM × R-GFP mice to MI at 10 weeks of age during a 6 week tamoxifen labeling protocol (Fig. 3k and Extended Data Fig. 6d-f). (nih.gov)