Myeloproliferative DisordersPrimary MyelofibrosisThrombocytosisSplenomegalyReceptor, Fibroblast Growth Factor, Type 1Polycythemia VeraJanus Kinase 2Bone MarrowThrombocythemia, EssentialLeukemia, Myelomonocytic, JuvenileLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLeukemia, Myelomonocytic, ChronicSyndromeReceptors, ThrombopoietinHematopoiesis, ExtramedullaryFusion Proteins, bcr-ablLeukocytosisGenes, ablMyelodysplastic-Myeloproliferative DiseasesOncogene Proteins, FusionSTAT5 Transcription FactorHematopoietic Stem CellsMutationfms-Like Tyrosine Kinase 3Leukemia, Myeloid, AcuteBone Marrow TransplantationLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeMyelodysplastic SyndromesBone Marrow NeoplasmsBone Marrow CellsGene Expression Regulation, LeukemicCell Transformation, NeoplasticDown SyndromeBenzamidesMutation, MissenseMyeloid CellsLeukemia, Neutrophilic, ChronicHematopoiesisLeukemiaPyrimidinesRetroviridaeTranslocation, GeneticPiperazinesReceptors, ErythropoietinDisease Models, AnimalMice, Inbred C57BLSignal Transduction