Primary MyelofibrosisMyeloproliferative DisordersMyelodysplastic SyndromesJanus Kinase 2Thrombocythemia, EssentialPolycythemia VeraMyelodysplastic-Myeloproliferative DiseasesReceptors, ThrombopoietinThrombocytosisAnemia, RefractoryLeukemia, Myelomonocytic, ChronicSplenomegalyBone MarrowBone Marrow NeoplasmsAnemia, Refractory, with Excess of BlastsMutationLeukemia, Myeloid, AcuteMegasphaeraSyndromeLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativePrognosisKaryotypingSea-Blue Histiocyte SyndromeLeukemia, MyeloidLeukemia, Myelomonocytic, JuvenileAnemia, SideroblasticChromosomes, Human, Pair 5Mutation, MissenseHematopoiesis, ExtramedullaryDisease ProgressionHematopoietic Stem CellsHematologic NeoplasmsProto-Oncogene Proteins c-cblPlatelet CountAmino Acid SubstitutionLeukemiaBlast CrisisLeukemia, Myelogenous, Chronic, BCR-ABL PositiveHematologyBone Marrow DiseasesAzacitidinePhiladelphia ChromosomeChromosome AberrationsWorld Health OrganizationPancytopeniaJanus KinasesThalidomideSurvival RateMonosomyTreatment OutcomeDNA Mutational AnalysisBone Marrow CellsPreleukemiaSTAT5 Transcription FactorMyeloid Progenitor CellsReticulinMegakaryocyte Progenitor CellsCell Transformation, NeoplasticChromosomes, Human, Pair 7Megakaryocyte-Erythroid Progenitor CellsProtein Kinase InhibitorsRisk FactorsThrombopoietinAcute DiseaseAnemia, AplasticHematopoietic Stem Cell TransplantationClonal EvolutionCytogenetic AnalysisHematopoiesisAntigens, CD34Bone Marrow ExaminationNeoplasms, Second PrimaryChromosome DeletionPoint MutationOsteosclerosisPyrazolesThrombocytopeniaAntineoplastic AgentsMyelopoiesisBlood Cell CountFusion Proteins, bcr-ablProto-Oncogene ProteinsGene Knock-In TechniquesDown SyndromeGranulocyte Precursor CellsTransplantation, HomologousErythropoietinCell ProliferationCytogeneticsSurvival AnalysisTrisomyLeukemia, Megakaryoblastic, AcuteFatal OutcomeAntimetabolites, Antineoplastic