Myeloproliferative DisordersMyelodysplastic-Myeloproliferative DiseasesMyelodysplastic SyndromesAnemia, RefractoryLeukemia, Myelomonocytic, ChronicThrombocytosisAnemia, SideroblasticPolycythemia VeraJanus Kinase 2Primary MyelofibrosisThrombocythemia, EssentialLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLeukemia, Myelomonocytic, JuvenileSplenomegalyHematopoiesis, ExtramedullaryFusion Proteins, bcr-ablReceptors, ThrombopoietinBone MarrowLeukemia, Myeloid, AcuteLeukocytosisGenes, ablOncogene Proteins, FusionSTAT5 Transcription FactorHematopoietic Stem Cellsfms-Like Tyrosine Kinase 3Bone Marrow TransplantationMutationAnemia, Refractory, with Excess of BlastsBone Marrow CellsGene Expression Regulation, LeukemicCell Transformation, NeoplasticLeukemiaBenzamidesHematopoiesisMyeloid CellsLeukemia, MyeloidTranslocation, GeneticPyrimidinesRetroviridaeLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeReceptors, ErythropoietinMutation, MissensePiperazinesMice, Inbred C57BLBone Marrow NeoplasmsChromosomes, Human, Pair 5Disease Models, AnimalSignal TransductionProtein-Tyrosine KinasesTransduction, GeneticCell ProliferationProto-Oncogene ProteinsMice, KnockoutFlow CytometryLeukemia, Neutrophilic, ChronicPhenotypeMice, Inbred BALB CKaryotypingMegakaryocytesPreleukemiaMice, TransgenicBlast CrisisChromosome AberrationsMonosomy