Multiple MyelomaMyelodysplastic SyndromesMyeloproliferative DisordersBone MarrowJanus Kinase 2Primary MyelofibrosisBone Marrow CellsMyelodysplastic-Myeloproliferative DiseasesPolycythemia VeraBone DiseasesThrombocythemia, EssentialAnemia, RefractoryBone Marrow NeoplasmsLeukemia, Myelomonocytic, ChronicBone Marrow TransplantationOsteolysisReceptors, ThrombopoietinAnemia, Refractory, with Excess of BlastsLeukemia, Myeloid, AcuteBone and BonesThrombocytosisSyndromeOsteoclastsBone Marrow DiseasesHematopoietic Stem CellsLeukemia, MyeloidLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeAnemia, SideroblasticLeukemia, Myelomonocytic, JuvenileMutationBone Marrow ExaminationOsteoblastsBone ResorptionChromosomes, Human, Pair 5LeukemiaHematologic NeoplasmsBone NeoplasmsSplenomegalyLeukemia, Myelogenous, Chronic, BCR-ABL PositiveProto-Oncogene Proteins c-cblPrognosisKaryotypingThalidomideHematopoiesisAzacitidineChromosome AberrationsDiphosphonatesBlast CrisisAnemia, AplasticPlasma CellsBone RemodelingPhiladelphia ChromosomeMegakaryocytesTreatment OutcomeOsteoprotegerinPreleukemiaMyeloid Progenitor CellsPancytopeniaTransplantation, HomologousHematologyMonosomyMyeloma ProteinsHematopoietic Stem Cell TransplantationAntigens, CD34Janus KinasesDNA Mutational AnalysisMice, SCIDDisease ProgressionColony-Forming Units AssayMegakaryocyte Progenitor CellsAcute DiseaseSTAT5 Transcription FactorChromosomes, Human, Pair 7Mice, Inbred C57BLCell Transformation, NeoplasticFlow CytometryBone DensityMegakaryocyte-Erythroid Progenitor CellsAntineoplastic AgentsGranulocytesCytogenetic AnalysisMyelopoiesisCell ProliferationTransplantation, AutologousNeoplasms, Second PrimaryClonal EvolutionCell DifferentiationMutation, MissenseChromosome DeletionBlood Cell CountFusion Proteins, bcr-ablGranulocyte Precursor CellsWhole-Body IrradiationCytogeneticsTranslocation, GeneticSurvival AnalysisImmunophenotypingHematologic DiseasesErythropoietinGranulocyte Colony-Stimulating Factor