Myelodysplastic SyndromesMyeloproliferative DisordersMyelodysplastic-Myeloproliferative DiseasesJanus Kinase 2Primary MyelofibrosisPolycythemia VeraThrombocythemia, EssentialLeukemia, Myeloid, AcuteMastocytosis, SystemicAnemia, RefractoryNeoplasms, Second PrimaryLeukemia, Myelomonocytic, ChronicLeukemia, MyeloidBone Marrow NeoplasmsReceptors, ThrombopoietinAnemia, Refractory, with Excess of BlastsHematologic NeoplasmsMutationThrombocytosisSyndromeLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeBone MarrowLeukemia, Myelomonocytic, JuvenileAnemia, SideroblasticChromosomes, Human, Pair 5Proto-Oncogene Proteins c-cblSplenomegalyHematopoietic Stem CellsAzacitidineLeukemiaLeukemia, Myelogenous, Chronic, BCR-ABL PositiveKaryotypingPrognosisPhiladelphia ChromosomeBlast CrisisChromosome AberrationsBone Marrow DiseasesHematologyMonosomyPreleukemiaDNA Mutational AnalysisMyeloid Progenitor CellsJanus KinasesTreatment OutcomeThalidomideMegakaryocyte Progenitor CellsBone Marrow CellsSTAT5 Transcription FactorNeoplasmsMegakaryocytesChromosomes, Human, Pair 7Megakaryocyte-Erythroid Progenitor CellsCell Transformation, NeoplasticDisease ProgressionMutation, MissensePancytopeniaAnemia, AplasticClonal EvolutionCytogenetic AnalysisChromosome DeletionAcute DiseaseMyelopoiesisPancreatic NeoplasmsFusion Proteins, bcr-ablAmino Acid SubstitutionPoint MutationProtein Kinase InhibitorsGene Knock-In TechniquesAntineoplastic AgentsDown SyndromeGranulocyte Precursor CellsHematopoietic Stem Cell TransplantationCytogeneticsHematopoiesisProto-Oncogene ProteinsTrisomyTranslocation, GeneticAntigens, CD34Cell ProliferationAntimetabolites, AntineoplasticChromosomes, Human, Pair 8ErythropoietinSurvival AnalysisBone Marrow ExaminationIron OverloadNeoplasms, Cystic, Mucinous, and SerousChromosomes, Human, Pair 20In Situ Hybridization, FluorescenceBlood Cell CountRetrospective StudiesExonsPhenotypeErythrocyte TransfusionTransplantation, HomologousCohort StudiesCore Binding Factor Alpha 2 SubunitHematologic DiseasesHematologic AgentsCase-Control StudiesSurvival Rate