Myeloproliferative DisordersMyelodysplastic-Myeloproliferative DiseasesMyelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicAnemia, RefractoryThrombocytosisAnemia, SideroblasticPolycythemia VeraJanus Kinase 2Primary MyelofibrosisThrombocythemia, EssentialLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLeukemia, Myelomonocytic, JuvenileSplenomegalyHematopoiesis, ExtramedullaryFusion Proteins, bcr-ablReceptors, ThrombopoietinBone MarrowGenes, ablLeukocytosisOncogene Proteins, FusionSTAT5 Transcription FactorLeukemia, Myeloid, AcuteHematopoietic Stem Cellsfms-Like Tyrosine Kinase 3Bone Marrow TransplantationMutationBone Marrow CellsGene Expression Regulation, LeukemicCell Transformation, NeoplasticLeukemiaAnemia, Refractory, with Excess of BlastsBenzamidesMyeloid CellsHematopoiesisRetroviridaePyrimidinesTranslocation, GeneticLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeReceptors, ErythropoietinMutation, MissensePiperazinesLeukemia, MyeloidMice, Inbred C57BLBone Marrow NeoplasmsDisease Models, AnimalSignal TransductionProtein-Tyrosine KinasesTransduction, GeneticCell ProliferationProto-Oncogene ProteinsChromosomes, Human, Pair 5Mice, KnockoutLeukemia, Neutrophilic, ChronicPhenotypeFlow CytometryMice, Inbred BALB CMice, TransgenicMegakaryocytesBlast CrisisKaryotypingSarcoma Viruses, MurineGranulocytes