Myeloproliferative DisordersPrimary MyelofibrosisPolycythemia VeraJanus Kinase 2Thrombocythemia, EssentialThrombocytosisSplenomegalyHematopoiesis, ExtramedullaryLeukemia, Myelogenous, Chronic, BCR-ABL PositiveLeukemia, Myelomonocytic, JuvenileReceptors, ThrombopoietinLeukemia, Myelomonocytic, ChronicBone MarrowFusion Proteins, bcr-ablLeukocytosisSTAT5 Transcription FactorGenes, ablOncogene Proteins, FusionHematopoietic Stem CellsMutationBone Marrow Transplantationfms-Like Tyrosine Kinase 3Myelodysplastic-Myeloproliferative DiseasesLeukemia, Myeloid, AcuteMegakaryocytesBone Marrow CellsCell Transformation, NeoplasticReticulinGene Expression Regulation, LeukemicBenzamidesLeukemiaOsteosclerosisHematopoiesisMyeloid CellsLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeMutation, MissenseBone Marrow NeoplasmsRetroviridaeThrombopoietinPyrimidinesReceptors, ErythropoietinProtein-Tyrosine KinasesMice, Inbred C57BLTransduction, GeneticSignal TransductionDisease Models, AnimalPiperazinesTranslocation, GeneticMyelodysplastic SyndromesProto-Oncogene ProteinsLeukemia, Megakaryoblastic, AcuteCell ProliferationOsteoarthropathy, Primary HypertrophicHypereosinophilic SyndromePolycythemiaHepatomegalyMice, KnockoutPhenotypeLeukemia, Neutrophilic, ChronicJanus KinasesLeukemia, MyeloidBlast CrisisSplenectomyMice, Inbred BALB CPlatelet CountPancytopeniaPyrazolesFlow CytometryMice, TransgenicGranulocytesBone Marrow ExaminationCells, CulturedSpleenPhiladelphia ChromosomeHydroxyureaSarcoma Viruses, MurineProtein Kinase InhibitorsJanus Kinase 1HematologyAntigens, CD34KaryotypingThrombocytopeniaAmino Acid SubstitutionPipobromanGATA1 Transcription FactorReceptor, Fibroblast Growth Factor, Type 1Anemia, MyelophthisicBlood Cell CountMoloney murine sarcoma virusBone Marrow DiseasesHematologic NeoplasmsAnemia, RefractoryMyelopoiesisCell Line, TumorCell LineDNA Mutational AnalysisColony-Forming Units AssayFatal OutcomeProto-Oncogene Proteins c-cbl