Cell CycleCell Line, TumorPoint MutationCell Cycle ProteinsMutation, MissenseMutationTumor Cells, CulturedCell DivisionCell Cycle CheckpointsTumor Suppressor Protein p53Cell ProliferationTumor Markers, BiologicalFrameshift MutationMolecular Sequence DataCell LineBase SequenceApoptosisNeoplasms, ExperimentalG1 PhaseGerm-Line MutationTumor Suppressor ProteinsTumor BurdenNeoplasmsSignal TransductionTumor Necrosis Factor-alphaRNA, MessengerMitosisAmino Acid SequenceDNA-Binding ProteinsS PhaseTransfectionGenes, Tumor SuppressorPolymerase Chain ReactionCell SurvivalCyclinsNeoplasm ProteinsGene Expression Regulation, NeoplasticAntineoplastic AgentsTranscription FactorsTime FactorsPhosphorylationCells, CulturedNeoplasm MetastasisFlow CytometryMice, NudeDNA, NeoplasmBlotting, WesternPedigreeImmunohistochemistryReverse Transcriptase Polymerase Chain ReactionBreast NeoplasmsAdenocarcinomaMammary Neoplasms, ExperimentalPhenotypeBrain NeoplasmsProtein-Serine-Threonine KinasesNeoplasm TransplantationWilms TumorG2 PhaseCell Transformation, NeoplasticTranscription, GeneticRetinoblastoma ProteinCyclin-Dependent Kinase Inhibitor p21Carcinoma, Ehrlich TumorMice, Inbred BALB CMice, Inbred C57BLDNAExonsColonic NeoplasmsDNA PrimersProtein BindingXenograft Model Antitumor AssaysAntigens, NeoplasmModels, BiologicalTransplantation, HeterologousDNA Mutational AnalysisNuclear ProteinsCyclin-Dependent Kinase Inhibitor p27Promoter Regions, GeneticGenes, p53Neovascularization, PathologicHeterozygoteAllelesProto-Oncogene ProteinsMenstrual CycleHeLa CellsMutation RateGene ExpressionTumor MicroenvironmentNeoplastic Cells, CirculatingAmino Acid SubstitutionOvarian NeoplasmsFibrosarcomaCell NucleusGene Expression RegulationDown-RegulationCarcinoid TumorLung NeoplasmsFibroblastsRNA, Small Interfering