Mutations in tumor suppressor genes tumor suppressor proteins. Medical search. Frequent questions

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Anatomy22

Cell Line, Tumor Tumor Cells, Cultured Cell Line Chromosomes, Human, Pair 3 Cells, Cultured Fibroblasts HeLa Cells Cell Nucleus Chromosomes, Human, Pair 9 HCT116 Cells Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 10 Chromosomes, Human, Pair 17 Cell Line, Transformed Chromosomes, Human, Pair 13 Chromosomes, Human, Pair 1 COS Cells NIH 3T3 Cells Epithelial Cells HEK293 Cells Chromosomes, Human, Pair 8 Cytoplasm

Organisms6

Mice, Nude Mice, Knockout Mice, Inbred C57BL Mice, Transgenic Mice, Inbred BALB C Adenoviridae

Diseases39

Cell Transformation, Neoplastic Neoplasms Kidney Neoplasms Wilms Tumor Breast Neoplasms Chromosome Deletion Adenocarcinoma Carcinoma, Renal Cell von Hippel-Lindau Disease Lung Neoplasms Neoplasms, Experimental Brain Neoplasms Carcinoma, Squamous Cell Skin Neoplasms Ovarian Neoplasms Liver Neoplasms Colonic Neoplasms Neurofibromatosis 2 Disease Progression Osteosarcoma Neoplasm Metastasis Carcinoma, Hepatocellular Glioblastoma Retinoblastoma Pancreatic Neoplasms Glioma Carcinoid Tumor Mammary Neoplasms, Experimental Neovascularization, Pathologic Adenoma Neuroendocrine Tumors Disease Models, Animal Prostatic Neoplasms Neoplasm Invasiveness Astrocytoma Urinary Bladder Neoplasms Mammary Neoplasms, Animal Chromosome Aberrations Rhabdoid Tumor

Chemicals and Drugs82

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Von Hippel-Lindau Tumor Suppressor Protein Tumor Suppressor Protein p14ARF Retinoblastoma Protein Proto-Oncogene Proteins c-mdm2 PTEN Phosphohydrolase Cyclin-Dependent Kinase Inhibitor p16 DNA-Binding Proteins Nuclear Proteins Transcription Factors Neurofibromin 2 DNA, Neoplasm Neoplasm Proteins Proto-Oncogene Proteins Adenomatous Polyposis Coli Protein RNA, Messenger Ubiquitin-Protein Ligases Cell Cycle Proteins Tumor Markers, Biological WT1 Proteins Proteins Cyclin-Dependent Kinase Inhibitor p21 Repressor Proteins Ligases Suppressor of Cytokine Signaling Proteins DNA Primers Carrier Proteins Protein-Serine-Threonine Kinases Cyclins Phosphoric Monoester Hydrolases RNA, Small Interfering Tumor Necrosis Factor-alpha Trans-Activators Membrane Proteins E2F Transcription Factors Recombinant Fusion Proteins DNA Acid Anhydride Hydrolases Neurofibromin 1 E2F1 Transcription Factor RNA, Neoplasm Intracellular Signaling Peptides and Proteins BRCA1 Protein MicroRNAs Azacitidine Apoptosis Regulatory Proteins Recombinant Proteins Cyclin-Dependent Kinase Inhibitor p15 beta Catenin Oncogene Proteins, Viral Drosophila Proteins DNA, Complementary Adaptor Proteins, Signal Transducing Transcription Factor DP1 Cytoskeletal Proteins Hypoxia-Inducible Factor 1, alpha Subunit Papillomavirus E7 Proteins Phosphoproteins Proteasome Endopeptidase Complex Retinoblastoma-Like Protein p107 Cyclin-Dependent Kinases Retinoblastoma-Binding Protein 1 Suppressor Factors, Immunologic Ubiquitin Retinoblastoma-Like Protein p130 Antineoplastic Agents Proto-Oncogene Proteins c-myc Carcinogens Protein Isoforms Cyclin-Dependent Kinase Inhibitor p27 Oncogene Proteins Genetic Markers Antigens, Polyomavirus Transforming Cadherins Luciferases Cyclin D1 DNA (Cytosine-5-)-Methyltransferase Adenovirus E1A Proteins Proto-Oncogene Proteins c-bcl-2 ras Proteins Proto-Oncogene Proteins c-akt

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Transfection Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction Blotting, Western Chromosome Mapping DNA Mutational Analysis Immunohistochemistry Tumor Burden Neoplasms, Experimental Models, Biological Gene Expression Profiling Transplantation, Heterologous Cloning, Molecular Oligonucleotide Array Sequence Analysis Immunoblotting Neoplasm Transplantation Immunoprecipitation Mammary Neoplasms, Experimental Precipitin Tests Flow Cytometry Sequence Analysis, DNA Xenograft Model Antitumor Assays Mutagenesis, Site-Directed Disease Models, Animal Neoplasm Staging Two-Hybrid System Techniques Immunoenzyme Techniques Blotting, Northern Gene Knockdown Techniques Sequence Alignment Pedigree In Situ Hybridization, Fluorescence

Phenomena and Processes84

Genes, Tumor Suppressor Mutation Genes, p53 Gene Expression Regulation, Neoplastic Loss of Heterozygosity Genes, Suppressor DNA Methylation Point Mutation Base Sequence Promoter Regions, Genetic Apoptosis Gene Silencing Transfection Gene Deletion Mutation, Missense Cell Cycle Signal Transduction Cell Proliferation Protein Binding Amino Acid Sequence Cell Division Down-Regulation Suppression, Genetic Transcription, Genetic Genes, Retinoblastoma Polymorphism, Single-Stranded Conformational Phosphorylation Alleles DNA Damage Chromosomes, Human, Pair 3 Exons Genes, p16 Protein Structure, Tertiary Germ-Line Mutation Transcriptional Activation Genes, Wilms Tumor CpG Islands Oncogenes Chromosome Deletion Phenotype Microsatellite Repeats Binding Sites Gene Expression Regulation RNA Interference Heterozygote Gene Expression Frameshift Mutation Genes, Neurofibromatosis 2 Chromosomes, Human, Pair 9 Genes, ras Genes, APC Epigenesis, Genetic Sequence Deletion Cell Aging Cell Survival Homozygote Sequence Homology, Amino Acid Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 10 Chromosomes, Human, Pair 17 Genes, DCC Up-Regulation G1 Phase Time Factors Cell Movement Ultraviolet Rays Chromosomes, Human, Pair 13 Mutagenesis Plasmids Cell Differentiation Genes, Neurofibromatosis 1 Chromosomes, Human, Pair 1 Genetic Markers Cell Growth Processes Genotype Genes, Reporter Ubiquitination Genetic Vectors DNA Repair Chromosomes, Human, Pair 8 Gene Dosage Tumor Microenvironment Alternative Splicing Chromosome Aberrations

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Genes, Tumor Suppressor Tumor Suppressor Protein p53 Tumor Suppressor Proteins Von Hippel-Lindau Tumor Suppressor Protein Mutation Cell Line, Tumor Tumor Suppressor Protein p14ARF Genes, p53 Gene Expression Regulation, Neoplastic Retinoblastoma Protein Loss of Heterozygosity Molecular Sequence Data Genes, Suppressor DNA Methylation Point Mutation Base Sequence Proto-Oncogene Proteins c-mdm2 PTEN Phosphohydrolase Cyclin-Dependent Kinase Inhibitor p16 Promoter Regions, Genetic DNA-Binding Proteins Nuclear Proteins Apoptosis Gene Silencing Cell Transformation, Neoplastic Transcription Factors Tumor Cells, Cultured Transfection Neurofibromin 2 Gene Deletion Mutation, Missense DNA, Neoplasm Cell Cycle Cell Line Signal Transduction Cell Proliferation Neoplasm Proteins Neoplasms Protein Binding Amino Acid Sequence Proto-Oncogene Proteins Adenomatous Polyposis Coli Protein RNA, Messenger Polymerase Chain Reaction Ubiquitin-Protein Ligases Cell Division Cell Cycle Proteins Tumor Markers, Biological Down-Regulation Suppression, Genetic WT1 Proteins Kidney Neoplasms Proteins Cyclin-Dependent Kinase Inhibitor p21 Reverse Transcriptase Polymerase Chain Reaction Transcription, Genetic Repressor Proteins Genes, Retinoblastoma Wilms Tumor Blotting, Western Chromosome Mapping Polymorphism, Single-Stranded Conformational Phosphorylation Alleles Ligases Breast Neoplasms DNA Damage Chromosomes, Human, Pair 3 DNA Mutational Analysis Immunohistochemistry Suppressor of Cytokine Signaling Proteins DNA Primers Exons Genes, p16 Protein Structure, Tertiary Carrier Proteins Germ-Line Mutation Transcriptional Activation Genes, Wilms Tumor Mice, Nude Protein-Serine-Threonine Kinases Tumor Burden Cyclins CpG Islands Oncogenes Phosphoric Monoester Hydrolases Chromosome Deletion Phenotype Adenocarcinoma Microsatellite Repeats Binding Sites Cells, Cultured Gene Expression Regulation RNA, Small Interfering Tumor Necrosis Factor-alpha RNA Interference Heterozygote Trans-Activators Fibroblasts Carcinoma, Renal Cell

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