Mutations in genes for proteins called presenilins. Medical search. Frequent questions

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Cell Line Endoplasmic Reticulum Fibroblasts Cells, Cultured Neurons Cell Membrane Subcellular Fractions Embryo, Mammalian CHO Cells Brain Golgi Apparatus Hippocampus

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Mice, Knockout Mice, Transgenic Caenorhabditis elegans Cricetinae Escherichia coli Saccharomyces cerevisiae

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Alzheimer Disease Syndrome Genetic Predisposition to Disease

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Presenilins Presenilin-2 Presenilin-1 Amyloid Precursor Protein Secretases Aspartic Acid Endopeptidases Membrane Proteins Amyloid beta-Protein Precursor Endopeptidases Receptors, Notch Amyloid beta-Peptides Dantrolene Helminth Proteins Codon, Nonsense Caenorhabditis elegans Proteins Recombinant Proteins Calcium Peptide Fragments Membrane Glycoproteins DNA Primers Codon DNA-Binding Proteins Transcription Factors DNA Mutant Proteins Bacterial Proteins

Analytical, Diagnostic and Therapeutic Techniques and Equipment16

Pedigree Transfection Amino Acid Substitution Polymerase Chain Reaction DNA Mutational Analysis Mutagenesis, Site-Directed Sequence Analysis, DNA Genetic Testing Blotting, Western Models, Molecular Chromosome Mapping Immunohistochemistry Genetic Complementation Test Cloning, Molecular Sequence Alignment Models, Genetic

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Alzheimer Disease

Phenomena and Processes44

Point Mutation Mutation, Missense Mutation Frameshift Mutation Germ-Line Mutation Amino Acid Sequence Protein Structure, Tertiary Mutation Rate Transfection Exons Base Sequence Heterozygote Amino Acid Substitution Sequence Homology, Amino Acid Alleles Protein Binding Polymorphism, Single-Stranded Conformational Signal Transduction Codon, Nonsense Genotype Homozygote Mutagenesis Protein Processing, Post-Translational Protein Transport Genes, Recessive Homeostasis Sequence Deletion Calcium Signaling Genes, Dominant Catalysis Suppression, Genetic Phenotype Codon Glycosylation Binding Sites Gene Deletion Founder Effect Genes, p53 Genetic Linkage Genetic Predisposition to Disease Consanguinity Plasmids Apoptosis Genes, Lethal

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Immunohistochemistry

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Molecular Sequence Data Amino Acid Sequence Base Sequence

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Genetic Testing

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Psychiatry and Psychology Phenomena and Processes Disciplines and Occupations Information Science Health Care

Presenilins Presenilin-2 Presenilin-1 Amyloid Precursor Protein Secretases Point Mutation Mutation, Missense Mutation Aspartic Acid Endopeptidases Membrane Proteins Alzheimer Disease Amyloid beta-Protein Precursor Endopeptidases Receptors, Notch Frameshift Mutation Germ-Line Mutation Amyloid beta-Peptides Molecular Sequence Data Pedigree Amino Acid Sequence Cell Line Protein Structure, Tertiary Mutation Rate Endoplasmic Reticulum Transfection Exons Base Sequence Heterozygote Dantrolene Amino Acid Substitution Mice, Knockout Sequence Homology, Amino Acid Polymerase Chain Reaction DNA Mutational Analysis Fibroblasts Alleles Protein Binding Helminth Proteins Polymorphism, Single-Stranded Conformational Cells, Cultured Neurons Mutagenesis, Site-Directed Mice, Transgenic Caenorhabditis elegans Signal Transduction Codon, Nonsense Genotype Homozygote Mutagenesis Protein Processing, Post-Translational Caenorhabditis elegans Proteins Sequence Analysis, DNA Cell Membrane Protein Transport Genes, Recessive Subcellular Fractions Embryo, Mammalian CHO Cells Recombinant Proteins Calcium Cricetinae Homeostasis Peptide Fragments Brain Sequence Deletion Calcium Signaling Membrane Glycoproteins Genes, Dominant Golgi Apparatus Genetic Testing Catalysis DNA Primers Escherichia coli Blotting, Western Suppression, Genetic Phenotype Models, Molecular Chromosome Mapping Codon Glycosylation Binding Sites Immunohistochemistry DNA-Binding Proteins Genetic Complementation Test Gene Deletion Founder Effect Transcription Factors Genes, p53 Syndrome Cloning, Molecular Sequence Alignment DNA Mutant Proteins Genetic Linkage Genetic Predisposition to Disease Saccharomyces cerevisiae Consanguinity Bacterial Proteins Plasmids Hippocampus Models, Genetic

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