Mutations in colon tumor suppressor proteins. Medical search. Frequent questions

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Anatomy19

Cell Line, Tumor Cell Line Tumor Cells, Cultured HCT116 Cells Cells, Cultured Fibroblasts HeLa Cells Cell Nucleus HT29 Cells Colon COS Cells Colon, Descending Cell Line, Transformed NIH 3T3 Cells Epithelial Cells Cytoplasm HEK293 Cells Intestinal Mucosa 3T3 Cells

Organisms7

Mice, Nude Mice, Inbred C57BL Mice, Knockout Rats, Inbred F344 Mice, Transgenic Mice, Inbred BALB C Drosophila

Diseases30

Colonic Neoplasms Cell Transformation, Neoplastic Neoplasms Adenocarcinoma Neoplasms, Experimental Kidney Neoplasms Breast Neoplasms Wilms Tumor Adenoma Liver Neoplasms Osteosarcoma Disease Progression Colorectal Neoplasms Neoplasm Metastasis Neurofibromatosis 2 Lung Neoplasms Carcinoma, Renal Cell von Hippel-Lindau Disease Disease Models, Animal Skin Neoplasms Brain Neoplasms Intestinal Neoplasms Carcinoma, Squamous Cell Carcinoma, Hepatocellular Retinoblastoma Precancerous Conditions Ovarian Neoplasms Neovascularization, Pathologic Adenomatous Polyposis Coli Glioblastoma

Chemicals and Drugs89

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Von Hippel-Lindau Tumor Suppressor Protein Tumor Suppressor Protein p14ARF Retinoblastoma Protein Proto-Oncogene Proteins c-mdm2 Nuclear Proteins Adenomatous Polyposis Coli Protein DNA-Binding Proteins Azoxymethane Transcription Factors Neurofibromin 2 Proto-Oncogene Proteins Neoplasm Proteins Cyclin-Dependent Kinase Inhibitor p16 RNA, Messenger Ubiquitin-Protein Ligases PTEN Phosphohydrolase Cell Cycle Proteins Cyclin-Dependent Kinase Inhibitor p21 Tumor Markers, Biological Carcinogens Repressor Proteins Proteins Ligases Cyclins DNA Primers Carrier Proteins E2F Transcription Factors DNA, Neoplasm 1,2-Dimethylhydrazine Dimethylhydrazines Protein-Serine-Threonine Kinases beta Catenin Trans-Activators Membrane Proteins Recombinant Fusion Proteins DNA E2F1 Transcription Factor Suppressor of Cytokine Signaling Proteins RNA, Small Interfering Transcription Factor DP1 Oncogene Proteins, Viral Cytoskeletal Proteins WT1 Proteins Recombinant Proteins Papillomavirus E7 Proteins Retinoblastoma-Binding Protein 1 Antineoplastic Agents Tumor Necrosis Factor-alpha Retinoblastoma-Like Protein p107 Proteasome Endopeptidase Complex Intracellular Signaling Peptides and Proteins Hypoxia-Inducible Factor 1, alpha Subunit Adaptor Proteins, Signal Transducing Ubiquitin Cyclin-Dependent Kinases Phosphoric Monoester Hydrolases DNA, Complementary Drosophila Proteins Phosphoproteins RNA, Neoplasm Apoptosis Regulatory Proteins Retinoblastoma-Like Protein p130 BRCA1 Protein Antigens, Polyomavirus Transforming Proto-Oncogene Proteins c-myc Neurofibromin 1 Ubiquitins Adenovirus E1A Proteins Protein Isoforms Luciferases Cyclin D1 Adenovirus E1B Proteins Cyclin-Dependent Kinase 4 Serine MicroRNAs Enzyme Inhibitors Suppressor Factors, Immunologic Glutathione Transferase Oncogene Proteins Adenovirus E4 Proteins Proto-Oncogene Proteins c-akt Proto-Oncogene Proteins c-bcl-2 Cyclin-Dependent Kinase Inhibitor p27 Anticarcinogenic Agents Hypoxia-Inducible Factor 1 Antibodies, Monoclonal ras Proteins

Analytical, Diagnostic and Therapeutic Techniques and Equipment31

Transfection Blotting, Western Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction Immunohistochemistry DNA Mutational Analysis Neoplasms, Experimental Tumor Burden Transplantation, Heterologous Neoplasm Transplantation Models, Biological Immunoblotting Mutagenesis, Site-Directed Cloning, Molecular Precipitin Tests Chromosome Mapping Pedigree Gene Expression Profiling Immunoprecipitation Amino Acid Substitution Disease Models, Animal Xenograft Model Antitumor Assays Models, Molecular Two-Hybrid System Techniques Sequence Alignment Flow Cytometry Immunoenzyme Techniques Oligonucleotide Array Sequence Analysis Microscopy, Fluorescence Sequence Analysis, DNA Blotting, Northern

Phenomena and Processes78

Genes, Tumor Suppressor Mutation Point Mutation Mutation, Missense Genes, p53 Gene Expression Regulation, Neoplastic Apoptosis Base Sequence Protein Binding Transfection Amino Acid Sequence Cell Cycle Signal Transduction Promoter Regions, Genetic Genes, Suppressor Cell Proliferation Cell Division Transcription, Genetic Phosphorylation Protein Structure, Tertiary DNA Damage Down-Regulation Binding Sites Suppression, Genetic Transcriptional Activation Genes, APC Frameshift Mutation DNA Methylation Loss of Heterozygosity Gene Deletion Gene Silencing Germ-Line Mutation Gene Expression Regulation Exons RNA Interference Phenotype Alleles Gene Expression Polymorphism, Single-Stranded Conformational Cell Survival Sequence Homology, Amino Acid Heterozygote Mutagenesis G1 Phase Sequence Deletion Genes, ras Cell Aging Ultraviolet Rays Time Factors Genes, Retinoblastoma Genes, Neurofibromatosis 2 Plasmids Oncogenes Up-Regulation Genes, p16 Amino Acid Substitution Genes, Reporter DNA Repair Cell Movement Cell Differentiation Microsatellite Repeats Ubiquitination Genotype Acetylation Homozygote Amino Acid Motifs Dose-Response Relationship, Drug CpG Islands Enzyme Activation Genes, Dominant Tumor Microenvironment Protein Stability Mutation Rate S Phase Protein Transport Genes, Wilms Tumor Gamma Rays Genetic Vectors

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Genes, Tumor Suppressor Colonic Neoplasms Von Hippel-Lindau Tumor Suppressor Protein Mutation Tumor Suppressor Protein p14ARF Cell Line, Tumor Point Mutation Retinoblastoma Protein Proto-Oncogene Proteins c-mdm2 Mutation, Missense Molecular Sequence Data Genes, p53 Gene Expression Regulation, Neoplastic Nuclear Proteins Apoptosis Base Sequence Adenomatous Polyposis Coli Protein DNA-Binding Proteins Cell Line Protein Binding Tumor Cells, Cultured Transfection Azoxymethane Transcription Factors Amino Acid Sequence Neurofibromin 2 Cell Cycle Proto-Oncogene Proteins Signal Transduction Promoter Regions, Genetic Genes, Suppressor Cell Transformation, Neoplastic Cell Proliferation Neoplasm Proteins Cyclin-Dependent Kinase Inhibitor p16 RNA, Messenger Ubiquitin-Protein Ligases Cell Division PTEN Phosphohydrolase Cell Cycle Proteins Transcription, Genetic Phosphorylation Cyclin-Dependent Kinase Inhibitor p21 Neoplasms Blotting, Western Protein Structure, Tertiary Adenocarcinoma Tumor Markers, Biological DNA Damage Carcinogens Down-Regulation Repressor Proteins Proteins Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction Ligases Binding Sites Cyclins Suppression, Genetic Mice, Nude Transcriptional Activation DNA Primers Genes, APC Frameshift Mutation Carrier Proteins E2F Transcription Factors DNA, Neoplasm 1,2-Dimethylhydrazine DNA Methylation HCT116 Cells Loss of Heterozygosity Dimethylhydrazines Protein-Serine-Threonine Kinases Gene Deletion Gene Silencing Germ-Line Mutation beta Catenin Trans-Activators Immunohistochemistry Gene Expression Regulation Membrane Proteins Recombinant Fusion Proteins Cells, Cultured Exons DNA Mutational Analysis RNA Interference Neoplasms, Experimental Fibroblasts HeLa Cells DNA E2F1 Transcription Factor Tumor Burden Suppressor of Cytokine Signaling Proteins RNA, Small Interfering Phenotype Kidney Neoplasms Transplantation, Heterologous Mice, Inbred C57BL

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