Mutations damage checkpoint pathway. Medical search. Frequent questions

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Anatomy19

Spindle Apparatus Kinetochores HeLa Cells Chromosomes, Fungal Cell Line Telomere Cell Line, Tumor Chromatin HCT116 Cells Cell Nucleus Chromosomes Fibroblasts Cells, Cultured Centrosome Tumor Cells, Cultured Oocytes Microtubules Embryo, Nonmammalian Chromatids

Organisms10

Saccharomyces cerevisiae Schizosaccharomyces Saccharomycetales Caenorhabditis elegans Escherichia coli Mice, Knockout Xenopus Xenopus laevis Drosophila Mice, Inbred C57BL

Diseases11

Genomic Instability Chromosomal Instability Cell Transformation, Neoplastic Chromosome Aberrations Ataxia Telangiectasia Neoplasms Nervous System Neoplasms Aneuploidy Syndrome Genetic Predisposition to Disease Polyploidy

Chemicals and Drugs104

Checkpoint Kinase 2 Cell Cycle Proteins Protein-Serine-Threonine Kinases Ataxia Telangiectasia Mutated Proteins Protein Kinases Saccharomyces cerevisiae Proteins DNA, Fungal DNA-Binding Proteins Nuclear Proteins Fungal Proteins Intracellular Signaling Peptides and Proteins Tumor Suppressor Proteins Hydroxyurea Schizosaccharomyces pombe Proteins Methyl Methanesulfonate cdc25 Phosphatases Tumor Suppressor Protein p53 CDC2 Protein Kinase Nocodazole Securin Exodeoxyribonucleases Cyclin B Replication Protein C Replication Protein A Nucleic Acid Synthesis Inhibitors Mad2 Proteins Chromosomal Proteins, Non-Histone Histones DNA DNA Helicases Repressor Proteins Mutagens Chromatin Caffeine Carrier Proteins Cyclin-Dependent Kinase Inhibitor p21 Cyclin-Dependent Kinases Cyclin-Dependent Kinase 2 Ribonucleotide Reductases Transcription Factors ras-GRF1 Recombinant Fusion Proteins Cdc20 Proteins BRCA1 Protein RNA, Small Interfering Staurosporine Phosphoproteins Cyclin B1 DNA Repair Enzymes Endodeoxyribonucleases Rad51 Recombinase Enzyme Inhibitors Xenopus Proteins Exonucleases DNA Primers Aphidicolin Telomere-Binding Proteins Adaptor Proteins, Signal Transducing Rad52 DNA Repair and Recombination Protein Endonucleases 14-3-3 Proteins Codon, Nonsense Ubiquitin-Protein Ligase Complexes Ubiquitin-Protein Ligases Anaphase-Promoting Complex-Cyclosome Aurora Kinases Recombinant Proteins Caenorhabditis elegans Proteins Calcium-Binding Proteins Cyclins Proto-Oncogene Proteins Adenosine Triphosphatases Multiprotein Complexes Protein-Tyrosine Kinases RNA, Messenger Cyclin A Serine Drosophila Proteins RecQ Helicases DNA, Single-Stranded Antineoplastic Agents Protein Kinase Inhibitors Trans-Activators Threonine DNA-Directed DNA Polymerase Alkylating Agents Phosphoprotein Phosphatases Aurora Kinase B DNA-Activated Protein Kinase Mutant Proteins Codon Proliferating Cell Nuclear Antigen Proteins Membrane Proteins Ubiquitin Topoisomerase I Inhibitors Bacterial Proteins DNA, Neoplasm Topoisomerase II Inhibitors Glutathione Transferase beta-Transducin Repeat-Containing Proteins Camptothecin Tissue Extracts DNA, Mitochondrial

Analytical, Diagnostic and Therapeutic Techniques and Equipment24

Models, Biological Dose-Response Relationship, Radiation Pedigree Mutagenesis, Site-Directed Amino Acid Substitution Flow Cytometry Polymerase Chain Reaction DNA Mutational Analysis Models, Genetic Blotting, Western Transfection Models, Molecular Immunoblotting Microscopy, Fluorescence Cloning, Molecular Sequence Alignment Sequence Analysis, DNA Immunoprecipitation Two-Hybrid System Techniques Genetic Testing Chromosome Mapping Genetic Complementation Test Comet Assay Precipitin Tests

Phenomena and Processes101

DNA Damage Genes, cdc Cell Cycle Cell Cycle Checkpoints DNA Replication S Phase G2 Phase Mitosis Phosphorylation Mutation Ultraviolet Rays Point Mutation DNA Repair Mutation, Missense Signal Transduction S Phase Cell Cycle Checkpoints M Phase Cell Cycle Checkpoints Genomic Instability G2 Phase Cell Cycle Checkpoints Gamma Rays Kinetochores DNA Breaks, Double-Stranded G1 Phase Anaphase Genes, Fungal Gene Expression Regulation, Fungal Frameshift Mutation Amino Acid Sequence Gene Deletion Radiation, Ionizing Chromosomes, Fungal Alleles Recombination, Genetic Protein Binding Base Sequence Germ-Line Mutation Telomere Dose-Response Relationship, Radiation Epistasis, Genetic Chromatin Mutagenesis Phenotype Chromosome Segregation Apoptosis Cell Division Genome, Fungal Protein Structure, Tertiary Recombinational DNA Repair Enzyme Activation Mutation Rate Meiosis Metaphase Suppression, Genetic Sequence Homology, Amino Acid Chromosomal Instability Heterozygote Amino Acid Substitution Exons Temperature Genotype Time Factors Radiation Tolerance Cell Survival Chromosomes Binding Sites RNA Interference Polymorphism, Single-Stranded Conformational Transfection Homozygote Plasmids Transcription, Genetic Genes, p53 Homologous Recombination Codon, Nonsense X-Rays Sequence Deletion Genes, Dominant Chromosome Aberrations Amino Acid Motifs Cell Death Gene Expression Regulation Genes, Recessive Kinetics Protein Transport Conserved Sequence DNA, Single-Stranded Cell Proliferation Genes, Lethal Codon Protein Processing, Post-Translational Aneuploidy Down-Regulation Genetic Predisposition to Disease Cell Aging G1 Phase Cell Cycle Checkpoints Dose-Response Relationship, Drug Promoter Regions, Genetic Chromatids Polyploidy Evolution, Molecular Founder Effect

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Health Care4

Ultraviolet Rays Dose-Response Relationship, Radiation Temperature Genetic Testing

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science Health Care

Checkpoint Kinase 2 DNA Damage Cell Cycle Proteins Protein-Serine-Threonine Kinases Ataxia Telangiectasia Mutated Proteins Protein Kinases Genes, cdc Cell Cycle Cell Cycle Checkpoints Saccharomyces cerevisiae Proteins DNA Replication S Phase Saccharomyces cerevisiae DNA, Fungal G2 Phase DNA-Binding Proteins Nuclear Proteins Mitosis Phosphorylation Mutation Fungal Proteins Intracellular Signaling Peptides and Proteins Ultraviolet Rays Tumor Suppressor Proteins Hydroxyurea Point Mutation DNA Repair Schizosaccharomyces Schizosaccharomyces pombe Proteins Methyl Methanesulfonate Mutation, Missense Signal Transduction cdc25 Phosphatases S Phase Cell Cycle Checkpoints M Phase Cell Cycle Checkpoints Spindle Apparatus Genomic Instability Tumor Suppressor Protein p53 CDC2 Protein Kinase Nocodazole Securin G2 Phase Cell Cycle Checkpoints Exodeoxyribonucleases Gamma Rays Cyclin B Kinetochores Replication Protein C DNA Breaks, Double-Stranded G1 Phase Anaphase Molecular Sequence Data Genes, Fungal Gene Expression Regulation, Fungal Frameshift Mutation Saccharomycetales HeLa Cells Amino Acid Sequence Replication Protein A Gene Deletion Models, Biological Radiation, Ionizing Nucleic Acid Synthesis Inhibitors Mad2 Proteins Chromosomes, Fungal Alleles Recombination, Genetic Chromosomal Proteins, Non-Histone Cell Line Protein Binding Histones Base Sequence Germ-Line Mutation DNA Telomere Cell Line, Tumor DNA Helicases Dose-Response Relationship, Radiation Epistasis, Genetic Repressor Proteins Mutagens Chromatin Caffeine Mutagenesis Carrier Proteins Phenotype Cyclin-Dependent Kinase Inhibitor p21 Chromosome Segregation Pedigree Apoptosis HCT116 Cells Cell Division Genome, Fungal Protein Structure, Tertiary Cyclin-Dependent Kinases Cyclin-Dependent Kinase 2 Recombinational DNA Repair Enzyme Activation Ribonucleotide Reductases Transcription Factors ras-GRF1

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