Cell CyclePoint MutationCell Cycle ProteinsMutation, MissenseMutationApoptosisCell Cycle CheckpointsFrameshift MutationG1 PhaseGerm-Line MutationMolecular Sequence DataCell DivisionMitosisBase SequenceCell LineS PhaseCell Line, TumorTumor Suppressor Protein p53CyclinsSignal TransductionAmino Acid SequencePedigreeCell ProliferationDNA-Binding ProteinsCells, CulturedCaspasesG2 PhaseCaspase 3PhosphorylationNuclear ProteinsTranscription FactorsMenstrual CycleCyclin-Dependent Kinase Inhibitor p21Protein-Serine-Threonine KinasesMutation RateTumor Cells, CulturedPolymerase Chain ReactionDNARNA, MessengerCell SurvivalRetinoblastoma ProteinExonsAmino Acid SubstitutionCyclin-Dependent Kinase Inhibitor p27HeterozygoteTransfectionProtein BindingFlow CytometryProto-Oncogene Proteins c-bcl-2Blotting, WesternG2 Phase Cell Cycle CheckpointsTime FactorsSaccharomyces cerevisiaeProto-Oncogene ProteinsHeLa CellsAllelesTranscription, GeneticCell NucleusTumor Suppressor ProteinsDNA FragmentationMutagenesis, Site-DirectedDNA PrimersDNA ReplicationGene Expression RegulationPhenotypeDNA Mutational AnalysisDNA DamageModels, BiologicalMutagenesisIn Situ Nick-End LabelingProtein Structure, TertiaryG0 PhaseCarrier ProteinsCDC2 Protein KinaseG1 Phase Cell Cycle CheckpointsPolymorphism, Single-Stranded ConformationalGenotypeSequence Homology, Amino AcidCyclin D1bcl-2-Associated X ProteinCyclin-Dependent Kinase 2Genes, p53Sequence Analysis, DNABinding SitesEnzyme ActivationPromoter Regions, GeneticSaccharomyces cerevisiae ProteinsAntineoplastic AgentsHomozygoteMitochondriaCyclin EReverse Transcriptase Polymerase Chain ReactionMembrane ProteinsFibroblastsGene DeletionGenes, cdcCell DifferentiationImmunohistochemistryGene ExpressionSequence Deletion