Myeloproliferative DisordersPolycythemia VeraJanus Kinase 2Primary MyelofibrosisThrombocythemia, EssentialThrombocytosisLeukemia, Myelomonocytic, ChronicLeukemia, Myelogenous, Chronic, BCR-ABL PositiveSplenomegalyLeukemia, Myelomonocytic, JuvenileReceptors, ThrombopoietinHematopoiesis, ExtramedullaryMutationFusion Proteins, bcr-ablMutation, MissenseBone MarrowLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeHematopoietic Stem CellsPoint MutationLeukocytosisGenes, ablOncogene Proteins, FusionLeukemia, Neutrophilic, ChronicSTAT5 Transcription FactorMyelodysplastic-Myeloproliferative DiseasesLeukemia, Myeloid, AcuteMyelodysplastic SyndromesBone Marrow TransplantationTranslocation, GeneticBone Marrow CellsBenzamidesHematopoiesisLeukemia, Megakaryoblastic, AcuteGene Expression Regulation, Leukemicfms-Like Tyrosine Kinase 3Cell Transformation, NeoplasticGranulocytesMegakaryocytesLeukemia, MyeloidReceptor, Fibroblast Growth Factor, Type 1Protein-Tyrosine KinasesPyrimidinesDown SyndromePolycythemiaMyeloid CellsLeukemiaSignal TransductionPiperazinesHypereosinophilic SyndromeBone Marrow NeoplasmsProto-Oncogene ProteinsHepatomegalyReceptors, ErythropoietinRetroviridaeJanus KinasesThrombopoietinDNA Mutational AnalysisDisease Models, AnimalAmino Acid SubstitutionPhenotypeMice, Inbred C57BLBudd-Chiari SyndromeChromosomes, Human, Pair 8Blast CrisisMyelopoiesisHydroxyureaChromosomes, Human, Pair 20Cell ProliferationX Chromosome InactivationMice, KnockoutPhiladelphia ChromosomeColony-Forming Units AssayMice, TransgenicPolymerase Chain ReactionChromosomes, Human, Pair 5Base SequenceExonsPlatelet CountFrameshift MutationAnemia, Refractory, with Excess of BlastsCells, CulturedTransduction, GeneticCell LineChronic DiseaseSarcoma Viruses, MurineMyeloid Progenitor CellsGerm-Line MutationAllelesMolecular Sequence DataValineGATA1 Transcription FactorMice, Inbred BALB CBlood Cell CountFlow CytometryHematologic NeoplasmsChromosomes, Human, XPedigreeBipolar DisorderHematologic DiseasesHydrops Fetalis