Ataxia TelangiectasiaAtaxia Telangiectasia Mutated ProteinsCheckpoint Kinase 2Cell Cycle ProteinsCell CycleTelangiectasisProtein-Serine-Threonine KinasesDNA DamageGenes, cdcProtein KinasesTelangiectasia, Hereditary HemorrhagicG2 PhaseTumor Suppressor ProteinsCell Cycle CheckpointsMitosisDNA-Binding ProteinsAtaxiaS PhaseDNA RepairHydroxyureaM Phase Cell Cycle CheckpointsG2 Phase Cell Cycle CheckpointsPhosphorylationNuclear ProteinsCerebellar AtaxiaDNA ReplicationRadiation, IonizingTumor Suppressor Protein p53Gamma RaysSpindle ApparatusMutationG1 Phasecdc25 PhosphatasesSaccharomyces cerevisiae ProteinsSchizosaccharomycesSchizosaccharomyces pombe ProteinsRadiation ToleranceCDC2 Protein KinaseRetinal TelangiectasisDNA Breaks, Double-StrandedUltraviolet RaysIntracellular Signaling Peptides and ProteinsSaccharomyces cerevisiaeFriedreich AtaxiaSignal TransductionApoptosisFungal ProteinsCell Line, TumorGenomic InstabilityHistonesCell LineCyclin-Dependent Kinase Inhibitor p21FibroblastsChromosomal InstabilityHeLa CellsMolecular Sequence DataCell DivisionS Phase Cell Cycle CheckpointsCyclin BDNA-Activated Protein KinaseMad2 ProteinsSpinocerebellar AtaxiasProtein Kinase InhibitorsNocodazoleCyclinsKinetochoresModels, BiologicalPhosphatidylinositol 3-KinasesGenes, FungalCell SurvivalDNA, FungalRNA, Small InterferingBase SequenceProtein BindingNucleic Acid Synthesis InhibitorsGene DeletionDose-Response Relationship, RadiationDNACell NucleusCells, CulturedReplication Protein ABRCA1 ProteinEnzyme ActivationPhenotypeCaffeineFlow CytometryAphidicolinAmino Acid SequenceCyclin-Dependent KinasesG1 Phase Cell Cycle CheckpointsMethyl MethanesulfonateCyclin B1RNA InterferenceDNA Repair EnzymesTumor Cells, CulturedBlotting, WesternCell ProliferationHCT116 CellsChromosome BreakageChromosomal Proteins, Non-Histone